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repressing transcription factor binding
(GO:0070491)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HMGB1 2 -1.590 3.400 2.856 -1.899 0.030 -0.792
HDAC9 1 -1.710 3.420
SKI 1 -1.870 2.800 -1.139 -0.588
KAT5 1 3.690 -1.200
NOC2L 1 1.010 -0.760 -0.322 0.179 0.516 0.566 0.288
NOC2L 1 1.010 -0.760
HDAC7 0 -0.840 1.260
HDAC4 0 1.730 -0.740
TCF3 0 0.270 -0.020
SRI 0 -0.540 1.260 -0.614 0.200 -0.437
CBX5 0 0.350 -0.490 0.332 -0.485 0.744 0.961 0.512
ZMYND8 0 1.480 -1.040
ZMYND8 0 1.480 -1.040 0.151 1.057 1.056 0.009
ZMYND8 0 1.480 -1.040 -0.793 0.183 0.741 0.799 0.587
ZMYND8 0 1.480 -1.040 -0.721 -0.104
TLE4 0 -0.380 0.600 0.116
TLE4 0 -0.380 0.600
HDAC5 0 -0.830 1.270
GMNN 0 0.620 -1.000
TBP 0 1.610 -1.170 -0.831
NFYB 0 -1.100 1.620 0.915
RUNX2 0
MYC 0 0.170 0.550 -2.443 -0.949 -0.454 -1.290
CTBP1 0 -0.410 0.390
CTBP1 0 -0.410 0.390 -0.293 -0.875 0.361 0.407 -0.049
CTBP1 0 -0.410 0.390 1.494 -0.398 0.504 0.897 -0.123
CTNNB1 0 0.490 -0.230
CTNNB1 0 0.490 -0.230 -0.415 0.628 0.215
RELA 0 -1.130 1.600 0.793
ZNF703 0 0.510 -0.810

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CBX5 Phosphorylation S14 -0.620 0.260 _RTADSSSS(ph)EDEEEYVVEK_
CBX5 Ubiquitylation K32 1.081 _VVK(gl)GQVEYLLK_
CBX5 Ubiquitylation K68 1.329 _NLDCPELISEFMK(gl)K_
CBX5 Ubiquitylation K69 0.893 _NLDCPELISEFMKK(gl)_
CBX5 Ubiquitylation K91 1.360 _K(gl)SNFSNSADDIK_
CBX5 Phosphorylation S92 0.064 -0.325 _RKS(ph)NFSNSADDIK_
CBX5 Ubiquitylation K102 1.233 1.344 _KSNFSNSADDIK(gl)SK_
CBX5 Ubiquitylation K154 0.568 0.740 _WKDTDEADLVLAK(gl)EANVK_
CTBP1 Ubiquitylation K279 0.443 _GGLVDEK(gl)ALAQALK_
CTBP1 Ubiquitylation K286 0.130 0.008 _ALAQALK(gl)EGR_
CTBP1 Phosphorylation S492 -1.548 _YPPGIVGVAPGGLPAAM(ox)EGIIPGGIPVTHNLPTVAHPS(ph)QAPSPNQPTK_
CTNNB1 Ubiquitylation K158 -1.265 _AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1 Ubiquitylation K180 -0.546 -0.636 _AAVM(ox)VHQLSK(gl)K_
CTNNB1 Ubiquitylation K181 -0.717 -0.729 _AAVMVHQLSKK(gl)_
CTNNB1 Phosphorylation S191 -0.024 0.129 _S(ph)PQMVSAIVR_
CTNNB1 Ubiquitylation K435 -0.350 _NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1 Ubiquitylation K496 -1.262 _LHYGLPVVVK(gl)_
CTNNB1 Phosphorylation S552 1.233 1.224 _RTS(ph)MGGTQQQFVEGVR_
CTNNB1 Phosphorylation T556 1.275 0.995 _RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1 Ubiquitylation K671 -0.941 -0.934 _MSEDKPQDYK(gl)K_
GMNN Ubiquitylation K50 -0.622 -0.151 _ENELSAGLSK(gl)R_
GMNN Phosphorylation S63 0.028 -0.793 _NDHLTSTTS(ph)SPGVIVPESSENK_
HDAC4 Phosphorylation S265 -0.390 _RS(ph)SPLLR_
HDAC4 Phosphorylation S266 -0.821 -0.598 _RSS(ph)PLLR_
HDAC4 Phosphorylation S632 -1.146 -0.837 _AQS(ph)SPASATFPVSVQEPPTKPR_
HDAC5 Phosphorylation S265 -0.390 _RS(ph)SPLLR_
HDAC5 Phosphorylation S266 -0.821 -0.598 _RSS(ph)PLLR_
HDAC7 Phosphorylation S181 -0.436 0.447 _KES(ph)APPSLR_
HDAC7 Phosphorylation S486 -0.969 -0.754 _AQS(ph)SPAAPASLSAPEPASQAR_
HDAC9 Phosphorylation S265 -0.390 _RS(ph)SPLLR_
HDAC9 Phosphorylation S266 -0.821 -0.598 _RSS(ph)PLLR_
HMGB1 Ubiquitylation K50 0.651 _WK(gl)TMSAK_
HMGB1 Ubiquitylation K59 1.001 0.009 _GK(gl)FEDMAK_
HMGB1 Ubiquitylation K114 0.314 _IK(gl)GEHPGLSIGDVAK_
HMGB1 Ubiquitylation K127 0.018 _IKGEHPGLSIGDVAK(gl)K_
HMGB1 Ubiquitylation K128 -0.407 _K(gl)LGEMWNNTAADDKQPYEK_
HMGB1 Ubiquitylation K157 0.850 _YEK(gl)DIAAYR_
KAT5 Ubiquitylation K230 -0.079 _MK(gl)NIECIELGR_
KAT5 Ubiquitylation K274 -0.149 _SLK(gl)CLQR_
MYC Phosphorylation S20 -1.444 -1.145 _PLNVS(ph)FTNR_
MYC Phosphorylation T72 -1.699 -1.813 _FELLPT(ph)PPLS(ph)PSRR_
MYC Phosphorylation S76 -1.777 -1.435 _FELLPTPPLS(ph)PSR_
MYC Phosphorylation S81 0.459 _S(ph)GLCSPSYVAVTPFSLR_
MYC Phosphorylation S85 0.199 0.073 _SGLCS(ph)PSYVAVTPFSLR_
MYC Ubiquitylation K162 -2.475 -1.259 _LVSEK(gl)LASYQAAR_
MYC Phosphorylation S295 -0.903 _SESGS(ph)PSAGGHSKPPHSPLVLK_
MYC Phosphorylation S307 -1.486 _SES(ph)GSPSAGGHSKPPHS(ph)PLVLK_
MYC Ubiquitylation K340 -2.449 _VK(gl)LDSVR_
MYC Ubiquitylation K403 -3.432 _DQIPELENNEK(gl)APK_
NOC2L Phosphorylation S49 -0.694 -0.494 _EAARS(ph)PDKPGGSPSASR_
NOC2L Phosphorylation S56 -1.635 -0.706 _SPDKPGGS(ph)PSASRR_
NOC2L Ubiquitylation K144 2.425 _K(gl)NSVPVTVAMVER_
NOC2L Ubiquitylation K226 -0.886 -0.310 _LLFGK(gl)VAK_
NOC2L Ubiquitylation K245 -1.994 _MLQPSSSPLWGK(gl)LR_
NOC2L Ubiquitylation K516 -0.170 _LSNVNLQEK(gl)AYR_
NOC2L Ubiquitylation K562 -0.563 _ECK(gl)VANYCR_
NOC2L Ubiquitylation K576 -1.085 _QVQQLLGK(gl)VQENSAYICSR_
NOC2L Ubiquitylation K637 0.193 _EIQLEISGK(gl)ER_
NOC2L Ubiquitylation K649 -1.048 -0.355 _LEDLNFPEIK(gl)R_
NOC2L Phosphorylation S672 0.375 0.458 _DLFDLNS(ph)SEEDDTEGFSER_
NOC2L Phosphorylation S673 0.408 0.312 _DLFDLNSS(ph)EEDDTEGFSER_
RUNX2 Phosphorylation S96 0.504 -0.399 _RFS(ph)PPSSSLQPGK_
RUNX2 Ubiquitylation K244 0.258 _NASAVMK(gl)NQVAR_
SKI Ubiquitylation K294 -0.126 -0.054 _AYILLSQDYTGK(gl)EEQAR_
SKI Ubiquitylation K365 -0.244 -0.390 _TLAGSSNK(gl)SLGCVHPR_
SKI Phosphorylation S431 -0.475 _VVS(ph)SPPCAAAVSR_
SKI Phosphorylation S432 -0.742 -0.438 _VVSS(ph)PPCAAAVSR_
SKI Phosphorylation S480 -1.160 -1.491 _LTVDTPGAPETLAPVAAPEEDKDS(ph)EAEVEVESR_
SRI Ubiquitylation K68 -0.196 _CLTQSGIAGGYK(gl)PFNLETCR_
SRI Ubiquitylation K127 -1.001 -0.186 _SGTVDPQELQK(gl)ALTTM(ox)GFR_
SRI Ubiquitylation K146 -0.939 -1.022 _LSPQAVNSIAK(gl)R_
TBP Ubiquitylation K181 -0.140 -0.577 _LDLK(gl)TIALR_
TBP Ubiquitylation K225 -0.596 _MVCTGAK(gl)SEEQSR_
TCF3 Phosphorylation S328 0.865 0.756 _AGAPGALS(ph)PSYDGGLHGLQSK_
TLE4 Phosphorylation S206 0.530 _SSS(ph)VSPSASFR_
TLE4 Phosphorylation S208 0.427 0.632 _SSSVS(ph)PSASFR_
TLE4 Phosphorylation S286 0.242 0.160 _DASSS(ph)PASTASSASSTSLK_
TLE4 Phosphorylation S292 -0.214 -0.084 _DAPIS(ph)PASIASSSSTPSSK_
ZMYND8 Phosphorylation S433 0.711 0.935 _LNFDMTAS(ph)PK_
ZMYND8 Phosphorylation S452 1.424 0.458 _RIS(ph)LSDMPR_
ZMYND8 Phosphorylation S487 0.758 0.909 _KATSSHFS(ph)ASEESM(ox)DFLDK_
ZMYND8 Phosphorylation S515 -0.248 _TGQAGSLS(ph)GSPKPFSPQLSAPITTK_
ZMYND8 Phosphorylation S517 -0.203 -0.342 _TGQAGSLSGS(ph)PKPFSPQLSAPITTK_
ZMYND8 Ubiquitylation K535 -0.785 _TDK(gl)TSTTGSILNLNLDR_
ZMYND8 Phosphorylation S574 -0.130 0.057 _ELSESVQQQSTPVPLIS(ph)PKR_
ZMYND8 Phosphorylation S695 0.298 0.206 _DKAS(ph)PEPEKDFSEK_
ZMYND8 Phosphorylation S764 0.454 _EPS(ph)PKQDVVGK_
ZMYND8 Phosphorylation S781 -0.958 _TPPSTTVGS(ph)HSPPETPVLTR_
ZMYND8 Phosphorylation S783 -0.726 -0.795 _TPPSTTVGSHS(ph)PPETPVLTR_
ZNF703 Phosphorylation S2 -0.222 _(ac)S(ph)DSPAGS(ph)NPRTPESSGSGSGGGGK_
ZNF703 Phosphorylation S8 -0.222 _(ac)S(ph)DSPAGS(ph)NPRTPESSGSGSGGGGK_
ZNF703 Phosphorylation T12 -0.699 0.126 _(ac)SDSPAGSNPRT(ph)PESSGSGSGGGGK_
ZNF703 Phosphorylation S252 -0.792 -0.340 _DQEPKPS(ph)PEPAAVSR_


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