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Query: KAT5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KAT5 1 -0.079 3.690 -1.200

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KAT5 Ubiquitylation K230 -0.079 _MK(gl)NIECIELGR_
KAT5 Ubiquitylation K274 -0.149 _SLK(gl)CLQR_

Background Information for KAT5:


Pubmed-KAT5 »
Uniprot-KAT5 »
Biogrid-KAT5 »
ProteomicsDB-KAT5 »

Tumorportal-KAT5 »
COSMIC-KAT5 »
GenomeRNAi-KAT5 »
Genecards-KAT5


Protein-protein Interactions for KAT5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ING3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RUVBL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015
Category members IP bait C20orf20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H2BA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MEAF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RUVBL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KAT5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Chromo_domain/shadow IPR000953 2.84
Category members Chromodomain-like IPR016197 2.29
Category members MOZ_SAS IPR002717 0.02
Category members Tudor-knot IPR025995 0.01
Category members Acyl_CoA_acyltransferase IPR016181 0


Protein complexes (CORUM database) featuring KAT5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 525 TIP60 histone acetylase complex Database 0.62
Category members Corum 2857 NuA4/Tip60 HAT complex Database 0.28
Category members Corum 798 NuA4/Tip60-HAT complex A Database 0.28
Category members Corum 787 NuA4/Tip60-HAT complex B Database 0.23
Category members Corum 2856 NuA4/Tip60 HAT complex Database 0.13
Category members Corum 528 NuA4/Tip60 HAT complex Database 0.07
Category members Corum 529 NuA4/Tip60 HAT complex Database 0.04


Categories featuring KAT5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members Pathway Pathway_978 PID_ATM_PATHWAY 0 4.31
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0000785 chromatin Database 2.59
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0030521 androgen receptor signaling pathway Database 1.25
Category members GO Category GO:0016573 histone acetylation Database 1.24
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_65 PID_MYC_ACTIV_PATHWAY 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_308 PID_AR_TF_PATHWAY 0 0.86
Category members GO Category GO:0004402 histone acetyltransferase activity Database 0.56
Category members GO Category GO:0032403 protein complex binding Database 0.49
Category members GO Category GO:0032777 Piccolo NuA4 histone acetyltransferase complex Database 0.39
Category members GO Category GO:0048471 perinuclear region of cytoplasm Database 0.39
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups Database 0.33
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members Pathway Pathway_858 PID_MYC_PATHWAY 0 0.17
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0050681 androgen receptor binding Database 0.12
Category members Pathway Pathway_200 PID_P73PATHWAY 0 0.11
Category members Pathway Pathway_735 ST_MYOCYTE_AD_PATHWAY 0 0.09
Category members Pathway Pathway_418 PID_ATF2_PATHWAY 0 0.08
Category members GO Category GO:0035267 NuA4 histone acetyltransferase complex Database 0.07
Category members Pathway Pathway_1005 ST_ERK1_ERK2_MAPK_PATHWAY 0 0.06
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Database 0
Category members GO Category GO:0032703 negative regulation of interleukin-2 production Database 0
Category members GO Category GO:0040008 regulation of growth Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070491 repressing transcription factor binding Database 0


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