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response to ionizing radiation
(GO:0010212)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
UIMC1 3 -1.570 2.710 0.307 -0.624
TOPBP1 3 -2.480 4.260 -0.269 0.277
BRCA1 2 0.200 -0.140 0.433 0.018 0.146
USP28 2 1.150 -0.550
NABP2 2 -0.740 1.510 2.632 2.887
NABP1 2 2.632 2.887
H2AFX 2 -0.474 -0.395 0.182 0.824 0.499
H2AFX 2
NEK1 1 -1.440 3.230
TP53BP2 1 1.060 -0.800 -0.399 -0.481
XRCC4 1 -0.240 0.070
PAXIP1 1 -1.460 2.910 -0.245 0.364 0.299
EYA3 1 -0.550 0.440
EYA3 1 -0.550 0.440
VCAM1 1 1.250 -0.880 -0.412 -0.373
RNF168 1 -0.220 -0.130 2.341
RNF168 1 0.210 -0.350 2.341
RRM1 1 0.717 1.039 0.509
KAT5 1 3.690 -1.200
CLK2 1 2.010 -1.310 0.077 0.840
AEN 1 2.220 -1.070
BAX 0 1.590 -1.170 0.811 0.359
DNMT3B 0 0.990 -0.100 0.783 0.015
EYA1 0 -0.440 -0.140
BABAM1 0
BRAT1 0 0.480 0.160 -0.672
RNF8 0 1.030 -0.670
STK11 0
TICRR 0 0.330 -0.710
ATM 0 0.398 0.474
BRE 0 -1.690 2.290 0.053 0.191 -0.048 0.149
BRE 0 -1.690 2.290 -1.215
LZIC 0 -0.390 -0.220 -0.081 0.340
FAM175A 0 -1.160 1.510
RFWD3 0 -0.420
XRCC6 0 0.960 -0.800
XRCC6 0 0.960 -0.800 -0.089 -0.758 0.145 0.033 0.140

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
AEN Ubiquitylation K109 -1.520 _ASGPLPSK(gl)CVAIDCEMVGTGPR_
ATM Ubiquitylation K307 -0.196 _GAYESTK(gl)WR_
ATM Ubiquitylation K331 -0.126 _GK(gl)YSSGFR_
ATM Ubiquitylation K385 -0.669 _ESSDYSVPCK(gl)R_
ATM Ubiquitylation K1101 -0.548 _LFQDTK(gl)GDSSR_
ATM Ubiquitylation K1109 -1.666 _LLK(gl)ALPLK_
ATM Ubiquitylation K1698 -1.026 _DASYTK(gl)ALK_
ATM Ubiquitylation K1738 -0.137 _SAAVTCLK(gl)NILATK_
ATM Ubiquitylation K2025 -1.497 _SIGEPDSLYGCGGGK(gl)MLQPITR_
BABAM1 Phosphorylation S7 -0.774 -0.248 _M(ox)EVAEPS(ph)S(ph)PTEEEEEEEEHSAEPR_
BABAM1 Phosphorylation S8 -0.593 -0.317 _(ac)MEVAEPSS(ph)PTEEEEEEEEHSAEPRPR_
BABAM1 Phosphorylation T10 -0.435 -0.371 _(ac)MEVAEPSSPT(ph)EEEEEEEEHSAEPR_
BABAM1 Phosphorylation S49 0.284 0.198 _S(ph)EGEGEAASADDGSLNTSGAGPK_
BABAM1 Phosphorylation T65 -0.439 _SEGEGEAASADDGSLNT(ph)SGAGPK_
BABAM1 Phosphorylation S66 0.479 -0.294 _SEGEGEAASADDGSLNTS(ph)GAGPK_
BABAM1 Ubiquitylation K117 -0.415 -0.148 _LESFNGSK(gl)TNALNVSQK_
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
BRAT1 Ubiquitylation K507 1.058 -1.843 _ELFPVLQK(gl)R_
BRAT1 Phosphorylation T581 1.274 _ASAVTAMGQLSSQGLHAPT(ph)SPEHAEAR_
BRAT1 Phosphorylation S582 1.370 _ASAVTAMGQLSSQGLHAPTS(ph)PEHAEAR_
BRAT1 Ubiquitylation K729 -1.711 _DK(gl)IASYSSLR_
BRAT1 Phosphorylation S742 1.211 0.349 _GS(ph)PNTASAEATLPR_
BRCA1 Phosphorylation S123 0.465 0.445 _KENNSPEHLKDEVS(ph)IIQSM(ox)GYR_
BRCA1 Phosphorylation S753 2.662 4.077 _VSNNAEDPKDLMLS(ph)GER_
BRCA1 Phosphorylation S1009 0.733 1.028 _KNLLEENFEEHSM(ox)S(ph)PER_
BRCA1 Phosphorylation S1546 1.821 2.105 _NYPS(ph)QEELIK_
BRCA1 Phosphorylation S1564 3.065 _VVDVEEQQLEES(ph)GPHDLTETSYLPR_
BRCA1 Phosphorylation S1664 1.120 _EKPELTAS(ph)TER_
BRE Ubiquitylation K26 -0.928 _NGK(gl)VGLDATNCLR_
BRE Ubiquitylation K41 -0.768 -0.586 _ITDLK(gl)SGCTSLTPGPNCDR_
BRE Ubiquitylation K162 0.838 _K(gl)NNWTGEFSAR_
DNMT3B Ubiquitylation K597 0.236 _ELGIK(gl)VGK_
DNMT3B Ubiquitylation K623 0.433 _HEGNIK(gl)YVNDVR_
EYA1 Ubiquitylation K513 -0.108 _NNVGGLLGPAK(gl)R_
EYA1 Ubiquitylation K587 -1.219 _IGK(gl)ESCFER_
EYA3 Phosphorylation S266 -1.629 _LSSGDPSTSPSLS(ph)QTTPSKDTDDQSR_
EYA3 Phosphorylation S297 3.021 _ADATSS(ph)QDSELER_
EYA3 Ubiquitylation K587 -1.219 _IGK(gl)ESCFER_
FAM175A Ubiquitylation K368 -0.236 _LLDTQDK(gl)R_
FAM175A Ubiquitylation K398 -1.202 _MK(gl)GFGEYSR_
FAM175A Phosphorylation S406 0.645 0.695 _GFGEYSRS(ph)PTF_
H2AFX Ubiquitylation K116 -0.071 _ATIAGGGVIPHIHK(gl)SLIGK_
H2AFX Ubiquitylation K120 0.702 0.181 _K(gl)TSATVGPK_
H2AFX Ubiquitylation K121 1.548 0.818 _SLIGK(gl)K(gl)GQQK_
H2AFX Ubiquitylation K122 1.238 -0.400 _SLIGK(gl)K(gl)GQQK_
H2AFX Ubiquitylation K126 1.132 _KGQQK(gl)TV_
H2AFX Ubiquitylation K128 -0.411 0.117 _KTSATVGPK(gl)APSGGKK_
H2AFX Phosphorylation S140 1.817 1.205 _KATQAS(ph)QEY_
KAT5 Ubiquitylation K230 -0.079 _MK(gl)NIECIELGR_
KAT5 Ubiquitylation K274 -0.149 _SLK(gl)CLQR_
NABP1 Ubiquitylation K8 -1.168 _(ac)TTETFVK(gl)DIKPGLK_
NABP2 Ubiquitylation K8 -1.168 _(ac)TTETFVK(gl)DIKPGLK_
NEK1 Phosphorylation S664 0.535 _SSDVSPPLGQHETGGS(ph)PSK_
NEK1 Phosphorylation S1052 0.195 0.324 _TCS(ph)LPDLSK_
NEK1 Phosphorylation S1126 0.472 0.693 _EQPGEEYS(ph)EEEESVLK_
RFWD3 Ubiquitylation K364 -0.539 0.428 _SSLLK(gl)EQMLR_
RFWD3 Ubiquitylation K583 -0.907 -0.404 _NTSSHVQELVAQK(gl)AR_
RNF168 Phosphorylation S134 0.945 _RAS(ph)EEEENKASEEYIQR_
RNF168 Ubiquitylation K227 -1.466 -1.424 _NTGDIQK(gl)YLTPK_
RNF168 Ubiquitylation K232 -1.889 _YLTPK(gl)SQFGSASHSEAVQEVR_
RNF168 Ubiquitylation K254 -1.121 _DSVSK(gl)DIDSSDRK_
RNF168 Ubiquitylation K334 -0.908 _ELCVLSHERPK(gl)TR_
RNF168 Ubiquitylation K341 -1.460 -1.996 _VPYSK(gl)ETAVMPCGR_
RNF168 Ubiquitylation K468 -0.810 -1.113 _QK(gl)GSPDEYHLR_
RNF168 Ubiquitylation K548 -2.498 _VSK(gl)SAHSLQPSISQK_
RNF8 Phosphorylation S157 -0.377 -0.438 _KFS(ph)LDELAGPGAEGPSNLK_
RRM1 Ubiquitylation K158 0.366 0.759 _SYLLK(gl)INGK_
RRM1 Ubiquitylation K376 0.409 0.370 _LYASYEK(gl)QGR_
RRM1 Ubiquitylation K414 0.015 _K(gl)SNQQNLGTIK_
RRM1 Ubiquitylation K465 -0.049 0.272 _K(gl)LAEVTK_
RRM1 Ubiquitylation K471 1.117 1.347 _LAEVTK(gl)VVVR_
RRM1 Ubiquitylation K496 0.699 1.559 _IIDINYYPVPEACLSNK(gl)R_
RRM1 Ubiquitylation K587 0.487 _VLKEK(gl)IAK_
RRM1 Ubiquitylation K590 -0.395 0.551 _IAK(gl)YGIR_
RRM1 Ubiquitylation K689 0.606 _TVWEISQK(gl)TVLK_
RRM1 Ubiquitylation K693 0.427 _TVLK(gl)MAAER_
RRM1 Ubiquitylation K733 0.748 _QGLK(gl)TGMYYLR_
RRM1 Ubiquitylation K754 -0.746 -1.217 _TRPAANPIQFTLNK(gl)EK_
RRM1 Ubiquitylation K756 -0.746 -1.217 _TRPAANPIQFTLNK(gl)EK_
STK11 Phosphorylation S31 0.437 0.073 _IDS(ph)TEVIYQPR_
STK11 Phosphorylation T32 1.256 0.248 _IDS(ph)TEVIYQPR_
TICRR Ubiquitylation K425 0.304 _TK(gl)EAEFQR_
TICRR Phosphorylation S441 0.009 _HVLQTAVADS(ph)PR_
TICRR Ubiquitylation K580 -1.770 _SLK(gl)MLNVAR_
TICRR Phosphorylation S599 -0.554 -0.542 _LHPDGS(ph)PDVAGEK_
TICRR Phosphorylation T815 -1.081 _LAGVLPTDFFSDDSM(ox)T(ph)QENKSPLLSVPFLSSAR_
TICRR Phosphorylation S820 -0.719 -0.737 _LAGVLPTDFFSDDSMTQENKS(ph)PLLSVPFLSSAR_
TICRR Phosphorylation S838 -0.549 0.417 _SVSGS(ph)PESDELQELR_
TICRR Phosphorylation S923 -0.863 -0.668 _NLFNQELLS(ph)PSK_
TICRR Phosphorylation S1001 -0.703 _SSDPGPDIGVVEES(ph)PEKGDEISLR_
TICRR Phosphorylation S1078 -0.627 -0.585 _SLLFGAMSEMIS(ph)PSEK_
TICRR Phosphorylation S1413 -0.558 _SIVECQPDASATPGVGTADS(ph)PAAPTDSRDDQK_
TICRR Phosphorylation S1750 -0.773 -0.709 _TPILEDFELEGVCQLPDQS(ph)PPR_
TOPBP1 Ubiquitylation K789 -0.950 _FQSK(gl)AFR_
TOPBP1 Phosphorylation S888 2.918 1.917 _NAVALSAS(ph)PQLK_
TP53BP2 Ubiquitylation K102 0.149 _SQDPSLK(gl)R_
TP53BP2 Ubiquitylation K152 0.224 _QQQQIEAQQQLLATK(gl)EQR_
TP53BP2 Ubiquitylation K224 -0.390 _LVEEIEQMNNLFQQK(gl)QR_
TP53BP2 Ubiquitylation K234 -0.113 _ELVLAVSK(gl)VEELTR_
TP53BP2 Ubiquitylation K268 -0.429 _LYK(gl)ELQLR_
TP53BP2 Ubiquitylation K283 -0.866 _NKLNQEQNAK(gl)LQQQR_
TP53BP2 Ubiquitylation K303 -0.302 _NSEVAVMDK(gl)R_
TP53BP2 Ubiquitylation K322 -2.045 _AALQQK(gl)ENLPVSSDGNLPQQAASAPSR_
TP53BP2 Phosphorylation S480 0.458 0.944 _NQS(ph)SEDILR_
TP53BP2 Phosphorylation S556 1.443 1.433 _VLLS(ph)PSIPSVGQDQTLSPGSK_
TP53BP2 Phosphorylation S569 1.774 _VLLS(ph)PSIPSVGQDQTLS(ph)PGSK_
TP53BP2 Phosphorylation S698 -0.309 -0.362 _IPRPLS(ph)PTK_
TP53BP2 Phosphorylation T700 -0.449 -0.429 _IPRPLSPT(ph)K_
TP53BP2 Phosphorylation S737 -0.172 -0.748 _RSS(ph)ITEPEGPNGPNIQK_
UIMC1 Ubiquitylation K19 -0.178 -1.011 _NLEK(gl)KDVETTSSVSVK_
UIMC1 Ubiquitylation K20 -0.247 -0.187 _K(gl)DVETTSSVSVK_
UIMC1 Ubiquitylation K31 0.443 0.015 _KDVETTSSVSVK(gl)R_
UIMC1 Phosphorylation S101 2.729 2.276 _EVNS(ph)QEEEEEELLRK_
UIMC1 Phosphorylation S140 2.351 _SRPLATGPSS(ph)QSHQEK_
UIMC1 Ubiquitylation K245 0.435 0.000 _GSAFLK(gl)AVQGSGDTSR_
UIMC1 Ubiquitylation K374 -0.119 -1.262 _TK(gl)DFQESSIK_
UIMC1 Ubiquitylation K382 0.111 -0.591 _TKDFQESSIK(gl)SLK_
UIMC1 Ubiquitylation K545 -0.089 -0.679 _TK(gl)SDSGTAAQTSLDIDKNEK_
UIMC1 Ubiquitylation K568 -1.100 -0.475 _CYLCK(gl)SLVPFR_
UIMC1 Ubiquitylation K608 0.301 -0.587 _ACSTVEGK(gl)WQQR_
UIMC1 Phosphorylation S654 0.098 0.120 _VPS(ph)PGM(ox)EEAGCSR_
UIMC1 Phosphorylation S678 0.108 -0.289 _RDLNES(ph)PVK_
USP28 Phosphorylation S495 2.593 2.418 _ESTSTESSS(ph)QDVESTFSSPEDSLPK_
USP28 Phosphorylation S1053 -0.658 -0.698 _EPPTIRPNS(ph)PYDLCSR_
VCAM1 Ubiquitylation K263 0.419 -0.113 _STLQIGK(gl)R_
VCAM1 Phosphorylation S276 0.013 _RDANSSFFDNSSS(ph)PHLLDQLK_
VCAM1 Ubiquitylation K293 -0.460 _NK(gl)INELELR_
VCAM1 Ubiquitylation K326 -0.856 _FQELQLQLEKAK(gl)_
VCAM1 Ubiquitylation K513 -1.965 _NIK(gl)QCLNQSQNFAEEMK_
VCAM1 Ubiquitylation K555 -0.739 -0.237 _INQQENSLTLEK(gl)LK_
VCAM1 Ubiquitylation K606 0.112 _ALLSALELKK(gl)_
VCAM1 Ubiquitylation K657 -0.600 0.172 _TQQIK(gl)SHEYNER_
VCAM1 Ubiquitylation K689 -0.011 _NLHNVLDSK(gl)SVEVETQK_
VCAM1 Ubiquitylation K770 -1.636 -0.056 _SK(gl)DASLVTNEDHQR_
VCAM1 Ubiquitylation K823 -1.207 -0.686 _LEADQSPK(gl)NSAILQNR_
VCAM1 Phosphorylation S834 1.282 _VDS(ph)LEFSLESQK_
VCAM1 Ubiquitylation K1022 -0.770 _SISELSDQYKQEK(gl)_
VCAM1 Phosphorylation S1255 2.400 _GDLETSNLQDMQS(ph)QEISGLKDCEIDAEEK_
VCAM1 Phosphorylation S1747 -0.145 _LQLQGLDLS(ph)SR_
VCAM1 Phosphorylation S1750 -1.171 -0.117 _S(ph)LLGIDTEDAIQGR_
VCAM1 Phosphorylation T1825 -0.475 _ITETGAVKPTGECSGEQSPDT(ph)NYEPPGEDK_
VCAM1 Ubiquitylation K2069 -0.699 _GELDTMSKK(gl)_
VCAM1 Ubiquitylation K2713 0.058 _MTAK(gl)ETELQR_
VCAM1 Ubiquitylation K2739 -1.524 _TAELQEELSGEK(gl)NR_
VCAM1 Phosphorylation S2996 -1.047 -1.005 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
VCAM1 Phosphorylation S3007 -0.910 -2.059 _GS(ph)PLLGPVVPGPS(ph)PIPSVTEK_
VCAM1 Phosphorylation S3119 -0.975 -0.328 _LALS(ph)PLSLGK_
VCAM1 Phosphorylation S3150 1.391 1.078 _VAQRS(ph)PVDSGTILR_
VCAM1 Phosphorylation S3175 1.052 0.884 _SVPVNNLPERS(ph)PTDSPR_
XRCC4 Ubiquitylation K178 0.552 _EALETDLYK(gl)R_
XRCC4 Ubiquitylation K197 0.264 _SLHNK(gl)LLNAAQER_
XRCC4 Phosphorylation S259 -0.552 1.634 _DDSIIS(ph)SLDVTDIAPSR_
XRCC4 Phosphorylation S260 -0.545 1.299 _DDSIISS(ph)LDVTDIAPSR_
XRCC4 Phosphorylation S320 0.439 1.683 _KEHISAENM(ox)S(ph)LETLR_
XRCC6 Phosphorylation S27 0.932 0.873 _TEGDEEAEEEQEENLEAS(ph)GDYK_
XRCC6 Ubiquitylation K114 -0.534 -0.728 _NIYVLQELDNPGAK(gl)R_
XRCC6 Ubiquitylation K123 -0.756 _ILELDQFK(gl)GQQGQK_
XRCC6 Ubiquitylation K129 0.079 -0.683 _ILELDQFKGQQGQK(gl)R_
XRCC6 Ubiquitylation K182 -1.603 _IMLFTNEDNPHGNDSAK(gl)ASR_
XRCC6 Ubiquitylation K282 -2.587 _ALK(gl)PPPIK_
XRCC6 Ubiquitylation K287 -1.436 -2.286 _ALKPPPIK(gl)LYR_
XRCC6 Ubiquitylation K299 -0.535 -0.792 _ETNEPVKTK(gl)TR_
XRCC6 Ubiquitylation K317 -0.584 -0.964 _TFNTSTGGLLLPSDTK(gl)R_
XRCC6 Ubiquitylation K331 -1.666 _QIILEK(gl)EETEELKR_
XRCC6 Ubiquitylation K338 -1.479 -1.003 _QIILEKEETEELK(gl)R_
XRCC6 Ubiquitylation K451 -1.713 -1.901 _MPFTEK(gl)IMATPEQVGK_
XRCC6 Phosphorylation T455 -0.085 0.348 _IMAT(ph)PEQVGK_
XRCC6 Ubiquitylation K461 0.239 -0.409 _IMATPEQVGK(gl)MK_
XRCC6 Ubiquitylation K463 -0.609 -0.641 _MK(gl)AIVEK_
XRCC6 Ubiquitylation K468 -1.302 -0.451 _AIVEK(gl)LR_
XRCC6 Phosphorylation S475 1.136 0.167 _S(ph)DSFENPVLQQHFR_
XRCC6 Phosphorylation S477 1.023 0.034 _SDS(ph)FENPVLQQHFR_
XRCC6 Ubiquitylation K516 -1.089 _VEAMNK(gl)R_
XRCC6 Phosphorylation S560 0.318 0.378 _VEYS(ph)EEELKTHISK_
XRCC6 Ubiquitylation K565 0.021 -0.887 _VEYSEEELK(gl)THISK_
XRCC6 Ubiquitylation K575 0.031 -0.121 _GTLGK(gl)FTVPMLK_
XRCC6 Ubiquitylation K591 0.474 0.187 _AYGLK(gl)SGLK_


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