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Query: FAM175A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FAM175A 0 2.614 -1.160 1.510

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FAM175A Phosphorylation S406 0.645 0.695 _GFGEYSRS(ph)PTF_
FAM175A Ubiquitylation K368 -0.236 _LLDTQDK(gl)R_
FAM175A Ubiquitylation K398 -1.202 _MK(gl)GFGEYSR_

Background Information for FAM175A:


Pubmed-FAM175A »
Uniprot-FAM175A »
Biogrid-FAM175A »
ProteomicsDB-FAM175A »

Tumorportal-FAM175A »
COSMIC-FAM175A »
GenomeRNAi-FAM175A »
Genecards-FAM175A


Protein-protein Interactions for FAM175A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BABAM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM175A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RABGGTB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TEKT4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FAM175A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FAM175 IPR023238 0.05
Category members FAM175_BRISC_cplx_Abro1_su IPR023240 0.05


Protein complexes (CORUM database) featuring FAM175A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2786 BRCA1 A complex Database 0.68


Categories featuring FAM175A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members Pathway Pathway_978 PID_ATM_PATHWAY 0 4.31
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0031593 polyubiquitin binding Database 0.38
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members GO Category GO:0070531 BRCA1-A complex Database 0.04
Category members GO Category GO:0045739 positive regulation of DNA repair Database 0.04
Category members GO Category GO:0031572 G2 DNA damage checkpoint Database 0


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