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Results for the Category
positive regulation of DNA repair
(GO:0045739)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
TRIM28 4 -0.250 -0.030 -0.451 -1.012 0.467 -0.209 -0.279
TRIM28 4 -0.250 -0.030
UIMC1 3 -1.570 2.710 0.307 -0.624
BRCA1 2 0.200 -0.140 0.433 0.018 0.146
ERCC8 2 -0.520 0.810 1.603 2.305
H2AFX 2 -0.474 -0.395 0.182 0.824 0.499
H2AFX 2
EYA3 1 -0.550 0.440
EYA3 1 -0.550 0.440
RNF168 1 -0.220 -0.130 2.341
RNF168 1 0.210 -0.350 2.341
TMEM161A 0 0.050 0.400 -0.241 -0.062
SIRT1 0 0.910 -0.910
APEX1 0 0.630 -0.180 -0.057 -0.077
EYA1 0 -0.440 -0.140
BABAM1 0
RNF8 0 1.030 -0.670
EGFR 0 -0.580 0.520 0.513 0.090
CEBPG 0 -1.150 1.620
BRE 0 -1.690 2.290 0.053 0.191 -0.048 0.149
BRE 0 -1.690 2.290 -1.215
FAM175A 0 -1.160 1.510
UBE2V2 0 -0.070 0.120
MGMT 0 -0.490 1.130 -0.643 0.047

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
APEX1 Ubiquitylation K25 -0.227 _GAVAEDGDELRTEPEAKK(gl)_
APEX1 Ubiquitylation K58 -0.215 _TSPSGK(gl)PATLK_
BABAM1 Phosphorylation S7 -0.774 -0.248 _M(ox)EVAEPS(ph)S(ph)PTEEEEEEEEHSAEPR_
BABAM1 Phosphorylation S8 -0.593 -0.317 _(ac)MEVAEPSS(ph)PTEEEEEEEEHSAEPRPR_
BABAM1 Phosphorylation T10 -0.435 -0.371 _(ac)MEVAEPSSPT(ph)EEEEEEEEHSAEPR_
BABAM1 Phosphorylation S49 0.284 0.198 _S(ph)EGEGEAASADDGSLNTSGAGPK_
BABAM1 Phosphorylation T65 -0.439 _SEGEGEAASADDGSLNT(ph)SGAGPK_
BABAM1 Phosphorylation S66 0.479 -0.294 _SEGEGEAASADDGSLNTS(ph)GAGPK_
BABAM1 Ubiquitylation K117 -0.415 -0.148 _LESFNGSK(gl)TNALNVSQK_
BRCA1 Phosphorylation S123 0.465 0.445 _KENNSPEHLKDEVS(ph)IIQSM(ox)GYR_
BRCA1 Phosphorylation S753 2.662 4.077 _VSNNAEDPKDLMLS(ph)GER_
BRCA1 Phosphorylation S1009 0.733 1.028 _KNLLEENFEEHSM(ox)S(ph)PER_
BRCA1 Phosphorylation S1546 1.821 2.105 _NYPS(ph)QEELIK_
BRCA1 Phosphorylation S1564 3.065 _VVDVEEQQLEES(ph)GPHDLTETSYLPR_
BRCA1 Phosphorylation S1664 1.120 _EKPELTAS(ph)TER_
BRE Ubiquitylation K26 -0.928 _NGK(gl)VGLDATNCLR_
BRE Ubiquitylation K41 -0.768 -0.586 _ITDLK(gl)SGCTSLTPGPNCDR_
BRE Ubiquitylation K162 0.838 _K(gl)NNWTGEFSAR_
CEBPG Ubiquitylation K98 -0.339 _VNQLK(gl)EENERLEAK_
CEBPG Ubiquitylation K113 0.032 0.273 _LLTK(gl)ELSVLK_
EGFR Phosphorylation T693 0.486 -0.139 _ELVEPLT(ph)PSGEAPNQALLR_
EGFR Phosphorylation S991 -0.041 _MHLPS(ph)PTDSNFYR_
EYA1 Ubiquitylation K513 -0.108 _NNVGGLLGPAK(gl)R_
EYA1 Ubiquitylation K587 -1.219 _IGK(gl)ESCFER_
EYA3 Phosphorylation S266 -1.629 _LSSGDPSTSPSLS(ph)QTTPSKDTDDQSR_
EYA3 Phosphorylation S297 3.021 _ADATSS(ph)QDSELER_
EYA3 Ubiquitylation K587 -1.219 _IGK(gl)ESCFER_
FAM175A Ubiquitylation K368 -0.236 _LLDTQDK(gl)R_
FAM175A Ubiquitylation K398 -1.202 _MK(gl)GFGEYSR_
FAM175A Phosphorylation S406 0.645 0.695 _GFGEYSRS(ph)PTF_
H2AFX Ubiquitylation K116 -0.071 _ATIAGGGVIPHIHK(gl)SLIGK_
H2AFX Ubiquitylation K120 0.702 0.181 _K(gl)TSATVGPK_
H2AFX Ubiquitylation K121 1.548 0.818 _SLIGK(gl)K(gl)GQQK_
H2AFX Ubiquitylation K122 1.238 -0.400 _SLIGK(gl)K(gl)GQQK_
H2AFX Ubiquitylation K126 1.132 _KGQQK(gl)TV_
H2AFX Ubiquitylation K128 -0.411 0.117 _KTSATVGPK(gl)APSGGKK_
H2AFX Phosphorylation S140 1.817 1.205 _KATQAS(ph)QEY_
MGMT Ubiquitylation K39 1.069 0.395 _(ac)MDKDCEMK(gl)R_
MGMT Ubiquitylation K209 0.024 -0.353 _LGK(gl)PGLGGSSGLAGAWLK_
RNF168 Phosphorylation S134 0.945 _RAS(ph)EEEENKASEEYIQR_
RNF168 Ubiquitylation K227 -1.466 -1.424 _NTGDIQK(gl)YLTPK_
RNF168 Ubiquitylation K232 -1.889 _YLTPK(gl)SQFGSASHSEAVQEVR_
RNF168 Ubiquitylation K254 -1.121 _DSVSK(gl)DIDSSDRK_
RNF168 Ubiquitylation K334 -0.908 _ELCVLSHERPK(gl)TR_
RNF168 Ubiquitylation K341 -1.460 -1.996 _VPYSK(gl)ETAVMPCGR_
RNF168 Ubiquitylation K468 -0.810 -1.113 _QK(gl)GSPDEYHLR_
RNF168 Ubiquitylation K548 -2.498 _VSK(gl)SAHSLQPSISQK_
RNF8 Phosphorylation S157 -0.377 -0.438 _KFS(ph)LDELAGPGAEGPSNLK_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_
TMEM161A Ubiquitylation K41 0.265 _YK(gl)HPSEEELR_
TMEM161A Ubiquitylation K54 -1.514 -1.327 _ALAGK(gl)PRPR_
TRIM28 Phosphorylation S4 -0.337 _(ac)AAS(ph)AAAASAAAASAASGSPGPGEGSAGGEK_
TRIM28 Phosphorylation S14 -0.154 _(ac)AASAAAASAAAAS(ph)AASGSPGPGEGSAGGEK_
TRIM28 Phosphorylation S17 -0.227 -0.026 _(ac)AASAAAASAAAASAAS(ph)GSPGPGEGSAGGEK_
TRIM28 Phosphorylation S19 -0.068 -0.189 _(ac)AASAAAASAAAASAASGS(ph)PGPGEGSAGGEK_
TRIM28 Phosphorylation S26 0.197 _(ac)AASAAAASAAAASAASGSPGPGEGS(ph)AGGEK_
TRIM28 Phosphorylation S41 0.373 _RSTAPSAAAS(ph)ASASAAASSPAGGGAEALELLEHCGVCR_
TRIM28 Phosphorylation S43 0.010 _RSTAPSAAASAS(ph)ASAAASSPAGGGAEALELLEHCGVCR_
TRIM28 Phosphorylation S49 -0.388 -0.110 _STAPSAAASASASAAAS(ph)SPAGGGAEALELLEHCGVCR_
TRIM28 Phosphorylation S50 -0.113 0.075 _RSTAPSAAASASASAAASS(ph)PAGGGAEALELLEHCGVCR_
TRIM28 Ubiquitylation K254 0.323 0.381 _K(gl)LLASLVK_
TRIM28 Ubiquitylation K261 1.520 0.923 _LLASLVK(gl)R_
TRIM28 Ubiquitylation K266 0.465 -0.005 _LGDK(gl)HATLQK_
TRIM28 Ubiquitylation K272 1.576 -0.085 _LGDKHATLQK(gl)STK_
TRIM28 Ubiquitylation K319 0.332 0.451 _VLVNDAQK(gl)VTEGQQER_
TRIM28 Ubiquitylation K337 0.976 _QHWTM(ox)TK(gl)IQK_
TRIM28 Ubiquitylation K340 0.112 -0.105 _IQK(gl)HQEHILR_
TRIM28 Ubiquitylation K407 -2.105 _SAEAFGK(gl)IVAERPGTNSTGPAPMAPPR_
TRIM28 Phosphorylation S471 3.215 2.215 _S(ph)RSGEGEVSGLM(ox)R_
TRIM28 Phosphorylation S473 3.049 2.476 _S(ph)GEGEVSGLMR_
TRIM28 Phosphorylation S489 0.264 0.043 _VS(ph)LERLDLDLTADSQPPVFK_
TRIM28 Phosphorylation T498 0.265 _VSLERLDLDLT(ph)ADSQPPVFK_
TRIM28 Phosphorylation T541 3.001 1.292 _GAAAAATGQPGTAPAGT(ph)PGAPPLAGMAIVK_
TRIM28 Phosphorylation S594 1.033 _LAS(ph)PSGSTSSGLEVVAPEGTSAPGGGPGTLDDSATICR_
TRIM28 Phosphorylation S624 -1.117 _LASPSGSTSSGLEVVAPEGTSAPGGGPGTLDDS(ph)ATICR_
TRIM28 Phosphorylation S681 1.735 _EEDGS(ph)LSLDGADSTGVVAK_
TRIM28 Phosphorylation S752 0.314 0.567 _LQEKLS(ph)PPYSSPQEFAQDVGR_
TRIM28 Phosphorylation S756 -0.408 _LSPPYS(ph)SPQEFAQDVGR_
TRIM28 Ubiquitylation K770 0.289 _MFK(gl)QFNK_
TRIM28 Ubiquitylation K779 0.334 2.706 _LTEDK(gl)ADVQSIIGLQR_
UBE2V2 Ubiquitylation K8 -0.337 -0.243 _(ac)AVSTGVK(gl)VPR_
UBE2V2 Ubiquitylation K66 -0.608 _IYSLK(gl)VECGPK_
UBE2V2 Ubiquitylation K72 -0.575 -0.545 _VECGPK(gl)YPEAPPSVR_
UBE2V2 Ubiquitylation K129 0.440 0.709 _LMMSK(gl)ENMK_
UIMC1 Ubiquitylation K19 -0.178 -1.011 _NLEK(gl)KDVETTSSVSVK_
UIMC1 Ubiquitylation K20 -0.247 -0.187 _K(gl)DVETTSSVSVK_
UIMC1 Ubiquitylation K31 0.443 0.015 _KDVETTSSVSVK(gl)R_
UIMC1 Phosphorylation S101 2.729 2.276 _EVNS(ph)QEEEEEELLRK_
UIMC1 Phosphorylation S140 2.351 _SRPLATGPSS(ph)QSHQEK_
UIMC1 Ubiquitylation K245 0.435 0.000 _GSAFLK(gl)AVQGSGDTSR_
UIMC1 Ubiquitylation K374 -0.119 -1.262 _TK(gl)DFQESSIK_
UIMC1 Ubiquitylation K382 0.111 -0.591 _TKDFQESSIK(gl)SLK_
UIMC1 Ubiquitylation K545 -0.089 -0.679 _TK(gl)SDSGTAAQTSLDIDKNEK_
UIMC1 Ubiquitylation K568 -1.100 -0.475 _CYLCK(gl)SLVPFR_
UIMC1 Ubiquitylation K608 0.301 -0.587 _ACSTVEGK(gl)WQQR_
UIMC1 Phosphorylation S654 0.098 0.120 _VPS(ph)PGM(ox)EEAGCSR_
UIMC1 Phosphorylation S678 0.108 -0.289 _RDLNES(ph)PVK_


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