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Query: RNF168

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNF168 1 1.362 -0.220 -0.130 2.341
RNF168 1 1.362 0.210 -0.350 2.341

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNF168 Phosphorylation S134 0.945 _RAS(ph)EEEENKASEEYIQR_
RNF168 Ubiquitylation K468 -0.810 -1.113 _QK(gl)GSPDEYHLR_
RNF168 Ubiquitylation K227 -1.466 -1.424 _NTGDIQK(gl)YLTPK_
RNF168 Ubiquitylation K232 -1.889 _YLTPK(gl)SQFGSASHSEAVQEVR_
RNF168 Ubiquitylation K341 -1.460 -1.996 _VPYSK(gl)ETAVMPCGR_
RNF168 Ubiquitylation K254 -1.121 _DSVSK(gl)DIDSSDRK_
RNF168 Ubiquitylation K334 -0.908 _ELCVLSHERPK(gl)TR_
RNF168 Ubiquitylation K548 -2.498 _VSK(gl)SAHSLQPSISQK_

Background Information for RNF168:


Pubmed-RNF168 »
Uniprot-RNF168 »
Biogrid-RNF168 »
ProteomicsDB-RNF168 »

Tumorportal-RNF168 »
COSMIC-RNF168 »
GenomeRNAi-RNF168 »
Genecards-RNF168


Protein-protein Interactions for RNF168
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RNF168 Cat. description Hein, Mann, Cell 2015
Category members IP bait TACC3 Cat. description Hein, Mann, Cell 2015


Protein Domains in RNF168
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_RING IPR001841 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring RNF168
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RNF168
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0043130 ubiquitin binding Database 1.22
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0035861 site of double-strand break Database 0.65
Category members GO Category GO:0070530 K63-linked polyubiquitin binding Database 0.35
Category members GO Category GO:0035518 histone H2A monoubiquitination Database 0.34
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0031491 nucleosome binding Database 0.24
Category members GO Category GO:0045190 isotype switching Database 0.11
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0045739 positive regulation of DNA repair Database 0.04
Category members GO Category GO:0036297 interstrand cross-link repair Database 0
Category members GO Category GO:0045900 negative regulation of translational elongation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070534 protein K63-linked ubiquitination Database 0
Category members GO Category GO:0070535 histone H2A K63-linked ubiquitination Database 0


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