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Query: EYA3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EYA3 1 2.242 -0.550 0.440

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EYA3 Ubiquitylation K587 -1.219 _IGK(gl)ESCFER_
EYA3 Phosphorylation S266 -1.629 _LSSGDPSTSPSLS(ph)QTTPSKDTDDQSR_
EYA3 Phosphorylation S297 3.021 _ADATSS(ph)QDSELER_

Background Information for EYA3:


Pubmed-EYA3 »
Uniprot-EYA3 »
Biogrid-EYA3 »
ProteomicsDB-EYA3 »

Tumorportal-EYA3 »
COSMIC-EYA3 »
GenomeRNAi-EYA3 »
Genecards-EYA3


Protein-protein Interactions for EYA3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SIX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCEAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EYA3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members EYA_dom IPR006545 0
Category members HAD-like_dom IPR023214 0


Protein complexes (CORUM database) featuring EYA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EYA3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0045739 positive regulation of DNA repair Database 0.04
Category members GO Category GO:0004725 protein tyrosine phosphatase activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006470 protein dephosphorylation Database 0
Category members GO Category GO:0007601 visual perception Database 0
Category members GO Category GO:0008138 protein tyrosine/serine/threonine phosphatase activity Database 0
Category members GO Category GO:0009653 anatomical structure morphogenesis Database 0
Category members GO Category GO:0016576 histone dephosphorylation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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