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Query: MGMT

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
MGMT 0 1.998 -0.490 1.130 -0.643 0.047

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
MGMT Ubiquitylation K39 1.069 0.395 _(ac)MDKDCEMK(gl)R_
MGMT Ubiquitylation K209 0.024 -0.353 _LGK(gl)PGLGGSSGLAGAWLK_

Background Information for MGMT:


Pubmed-MGMT »
Uniprot-MGMT »
Biogrid-MGMT »
ProteomicsDB-MGMT »

Tumorportal-MGMT »
COSMIC-MGMT »
GenomeRNAi-MGMT »
Genecards-MGMT


Protein-protein Interactions for MGMT
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in MGMT
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring MGMT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring MGMT
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members Pathway Pathway_338 REACTOME_DNA_REPAIR 0 8.18
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0009008 DNA-methyltransferase activity Database 0.32
Category members GO Category GO:0006266 DNA ligation Database 0.27
Category members GO Category GO:0006306 DNA methylation Database 0.22
Category members Disease phenotype Giant_cell_glioblastoma Giant cell glioblastoma Database 0.14
Category members Disease phenotype Gliosarcoma Gliosarcoma Database 0.14
Category members GO Category GO:0005509 calcium ion binding Database 0.11
Category members GO Category GO:0003824 catalytic activity Database 0.11
Category members GO Category GO:0045471 response to ethanol Database 0.1
Category members GO Category GO:0045739 positive regulation of DNA repair Database 0.04
Category members GO Category GO:0051593 response to folic acid Database 0.01
Category members GO Category GO:0006307 DNA dealkylation involved in DNA repair Database 0
Category members GO Category GO:0008168 methyltransferase activity Database 0
Category members GO Category GO:0009636 response to toxic substance Database 0
Category members GO Category GO:0014070 response to organic cyclic compound Database 0
Category members GO Category GO:0034599 cellular response to oxidative stress Database 0
Category members GO Category GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process Database 0
Category members GO Category GO:0060548 negative regulation of cell death Database 0
Category members GO Category GO:0060644 mammary gland epithelial cell differentiation Database 0
Category members GO Category GO:0071407 cellular response to organic cyclic compound Database 0


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