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response to toxic substance
(GO:0009636)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
ERCC6 4 -1.310 2.800 5.118 1.227 2.135
ERCC6 4 0.480 0.030 5.118 1.227 2.135
ERCC6 4 -1.310 2.800 0.074 0.258
ERCC6 4 0.480 0.030 0.074 0.258
MAPK9 1 0.110 -0.490
BLMH 1 0.710 -0.440 1.895 -1.446
EPHX1 1 -1.390 2.530 0.544 0.433
LYN 1 -1.790 3.770
LYN 1 -1.790 3.770
CPS1 0 -0.030 -0.030
FAS 0 1.380 -1.070
FAS 0 1.380 -1.070
CDH1 0 0.150 0.280 -0.623
WAPAL 0 -0.050 1.110 -0.551 0.359 0.266 -0.378 0.010
ASNS 0 -0.720 0.410 -0.182 1.244 1.020
BAX 0 1.590 -1.170 0.811 0.359
SCFD1 0 -0.210 0.810 -0.210 0.253 0.724 0.114 0.376
PTGR1 0 -0.590 0.630
RPS6KB1 0 0.850 -0.600
SRF 0 0.670 -1.020
CDKN1A 0 1.080 -0.750
MPST 0 -0.290 0.000 1.318
CCNB1 0 -0.410 -0.128 0.212 -0.166 -0.523
CDK4 0 1.930 -0.950
CDK4 0 1.930 -0.950 -0.510 0.013
MDM2 0 -0.210 0.080
SLC7A11 0 -0.760 1.480
GABRB1 0 0.040 -0.270
TK1 0 0.610 -0.460
CDK1 0 -0.370 0.080 -0.202 -0.884 -0.107 -0.097 -0.501
MGMT 0 -0.490 1.130 -0.643 0.047
BCL2 0 0.910 -0.740
TYMS 0 -1.190 1.570
CHUK 0 -0.480

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
ASNS Ubiquitylation K244 -0.611 -0.778 _ILFNNAVK(gl)K_
ASNS Ubiquitylation K245 -0.477 -0.859 _ILFNNAVKK(gl)_
ASNS Ubiquitylation K445 -1.075 _NGIEK(gl)HLLR_
ASNS Ubiquitylation K478 -0.512 -0.416 _EAFSDGITSVK(gl)NSWFK_
ASNS Ubiquitylation K513 -1.163 _TK(gl)EGYYYR_
ASNS Ubiquitylation K556 0.064 _TLTHYK(gl)SAVKA_
BAX Ubiquitylation K57 -1.174 _MGGEAPELALDPVPQDASTK(gl)K_
BAX Ubiquitylation K58 -1.718 -1.174 _MGGEAPELALDPVPQDASTKK(gl)_
BAX Ubiquitylation K64 0.708 1.306 _LSECLK(gl)R_
BCL2 Ubiquitylation K22 1.480 _YIHYK(gl)LSQR_
CCNB1 Ubiquitylation K18 -0.455 _AK(gl)INMAGAK_
CCNB1 Ubiquitylation K36 -1.833 -2.301 _VPTAPAATSK(gl)PGLRPR_
CCNB1 Ubiquitylation K59 -0.659 _VSEQLQAK(gl)MPMK_
CCNB1 Ubiquitylation K288 0.578 _QMEMK(gl)ILR_
CDK1 Ubiquitylation K6 0.011 -0.784 _(ac)M(ox)EDYTK(gl)IEK_
CDK1 Ubiquitylation K20 -0.327 -0.270 _IGEGTYGVVYK(gl)GR_
CDK1 Ubiquitylation K33 0.736 0.239 _TTGQVVAMK(gl)K_
CDK1 Ubiquitylation K34 -0.306 _TTGQVVAMKK(gl)_
CDK1 Ubiquitylation K58 0.312 -0.262 _EISLLK(gl)ELR_
CDK1 Ubiquitylation K136 -0.468 _DLK(gl)PQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K145 0.161 -0.954 _DLKPQNLLIDDK(gl)GTIK_
CDK1 Ubiquitylation K149 -0.038 _GTIK(gl)LADFGLAR_
CDK1 Ubiquitylation K251 -0.047 -1.236 _WK(gl)PGSLASHVK_
CDK1 Ubiquitylation K280 0.179 -1.210 _MLIYDPAK(gl)R_
CDK4 Ubiquitylation K142 -0.552 _DLK(gl)PENILVTSGGTVK_
CDK4 Ubiquitylation K211 -0.101 _K(gl)PLFCGNSEADQLGK_
CDK4 Phosphorylation S236 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Phosphorylation S249 0.095 _QDDS(ph)PSGASYGQDYDLS(ph)PSR_
CDK4 Ubiquitylation K297 0.247 0.052 _ALQHSYLHK(gl)DEGNPE_
CDK4 Phosphorylation S385 0.649 _HSSIS(ph)PVRLPLNSSLGAELSR_
CDK4 Phosphorylation S420 0.004 -0.202 _ES(ph)KGSPVFLPR_
CDK4 Phosphorylation S423 -0.155 -0.297 _GS(ph)PVFLPR_
CDK4 Phosphorylation T514 0.364 0.570 _DSKPIALKEEIVT(ph)PK_
CDK4 Phosphorylation S681 -2.532 -2.051 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation S685 -2.729 _HLLTDLPLPPELPGGDLS(ph)PPDS(ph)PEPK_
CDK4 Phosphorylation T692 -0.765 -1.849 _AIT(ph)PPQQPYK_
CDK4 Phosphorylation S1082 -1.661 -0.980 _KETTSGTSTEPVKNS(ph)SPAPPQPAPGK_
CDK4 Phosphorylation S1083 -1.093 -1.330 _NSS(ph)PAPPQPAPGK_
CDK4 Phosphorylation T1244 -0.956 _RT(ph)PTMPQEEAAACPPHILPPEK_
CDKN1A Ubiquitylation K188 -2.505 -1.077 _QTSMTDFYHSK(gl)R_
CHUK Ubiquitylation K296 -1.637 _GGPVDLTLK(gl)QPR_
CPS1 Phosphorylation S1278 -0.511 -1.077 _ASRSFPFVS(ph)K_
ERCC6 Phosphorylation S158 0.039 0.466 _IIEQLS(ph)PQAATSR_
ERCC6 Phosphorylation S212 -0.295 _IELDHAS(ph)LEEDAEPGPSSLGSMLMPVQETAWEELIR_
ERCC6 Ubiquitylation K255 0.184 -1.007 _TGQMTPFGTQIPQK(gl)QEK_
ERCC6 Ubiquitylation K258 0.830 -1.007 _TGQMTPFGTQIPQKQEK(gl)_
ERCC6 Phosphorylation T303 -1.105 _KAPAPVT(ph)PPAPVQNK_
ERCC6 Ubiquitylation K345 0.454 -0.211 _ALQFQGK(gl)VGLPK_
ERCC6 Ubiquitylation K606 0.305 _VAILHETGSYTHK(gl)K_
ERCC6 Ubiquitylation K607 0.278 _VAILHETGSYTHKK(gl)_
ERCC6 Ubiquitylation K663 -0.597 0.145 _NPNAAVTLACK(gl)QFR_
ERCC6 Ubiquitylation K729 1.490 0.510 _TAYK(gl)CACVLR_
ERCC6 Ubiquitylation K759 -0.019 _MSLSLPDK(gl)NEQVLFCR_
ERCC6 Ubiquitylation K774 0.041 1.536 _LTDEQHK(gl)VYQNFVDSK_
ERCC6 Ubiquitylation K783 0.262 -0.019 _VYQNFVDSK(gl)EVYR_
ERCC6 Ubiquitylation K955 -0.048 -0.623 _K(gl)QVTVYR_
ERCC6 Phosphorylation S1068 0.742 0.512 _KFPASNISVNDATS(ph)SEEKSEAK_
ERCC6 Phosphorylation S1142 0.830 0.891 _TSMPS(ph)GDESIDEK_
ERCC6 Phosphorylation S1146 1.367 0.961 _TSMPSGDES(ph)IDEK_
ERCC6 Ubiquitylation K1156 0.818 -0.034 _LGLSYK(gl)R_
ERCC6 Ubiquitylation K1295 0.149 0.443 _VAQDALK(gl)ALR_
ERCC6 Ubiquitylation K1327 -0.793 0.156 _GISGAPAGK(gl)K_
ERCC6 Ubiquitylation K1328 -0.793 0.232 _GISGAPAGKK(gl)_
ERCC6 Phosphorylation S1345 0.486 0.469 _NSNFSVQHPS(ph)STSPTEK_
ERCC6 Phosphorylation S1346 0.052 0.548 _NSNFSVQHPSS(ph)TSPTEK_
ERCC6 Phosphorylation T1347 0.180 0.745 _NSNFSVQHPSST(ph)SPTEK_
ERCC6 Phosphorylation S1348 0.238 0.374 _NSNFSVQHPSSTS(ph)PTEK_
ERCC6 Ubiquitylation K1352 -1.415 _NSNFSVQHPSSTSPTEK(gl)CQDGIMK_
ERCC6 Ubiquitylation K1359 0.923 _CQDGIMK(gl)K_
ERCC6 Ubiquitylation K1360 2.898 _CQDGIMKK(gl)_
ERCC6 Ubiquitylation K1363 -0.116 -0.707 _EGK(gl)DNVPEHFSGR_
ERCC6 Phosphorylation S1379 0.589 0.418 _AEDADS(ph)SSGPLASSSLLAK_
ERCC6 Ubiquitylation K1392 -0.822 -0.293 _AEDADSSSGPLASSSLLAK(gl)MR_
ERCC6 Ubiquitylation K1457 0.602 1.210 _EILQEFESK(gl)LSASQSCVFR_
ERCC6 Ubiquitylation K1487 -0.363 -0.266 _TSGGEGIWK(gl)LKPEYC_
FAS Phosphorylation S236 -0.027 _ENQGS(ph)HESPTLNPETVAINLSDVDLSK_
FAS Phosphorylation S239 0.266 _ENQGSHES(ph)PTLNPETVAINLSDVDLSK_
FAS Ubiquitylation K343 1.126 _IQTIILK(gl)DITSDSENSNFR_
GABRB1 Ubiquitylation K193 0.445 _SFVHGVTVK(gl)NR_
LYN Ubiquitylation K20 -0.592 _GKDSLSDDGVDLK(gl)TQPVR_
LYN Ubiquitylation K40 0.100 _DPTSNK(gl)QQRPVPESQLLPGQR_
LYN Phosphorylation S104 0.944 0.841 _DSLS(ph)DDGVDLK_
LYN Ubiquitylation K213 0.441 _HYQK(gl)QADGLCR_
LYN Ubiquitylation K477 -0.191 _VENCPDELYDIMK(gl)MCWK_
MAPK9 Phosphorylation Y185 3.533 _TACTNFMMTPY(ph)VVTR_
MDM2 Phosphorylation S166 0.576 1.068 _AIS(ph)ETEENSDELSGER_
MDM2 Ubiquitylation K334 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K336 -0.872 _ENWLPEDK(gl)GK_
MDM2 Ubiquitylation K363 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K364 0.883 _LENSTQAEEGFDVPDCK(gl)K_
MDM2 Ubiquitylation K473 0.806 _NK(gl)PCPVCR_
MGMT Ubiquitylation K39 1.069 0.395 _(ac)MDKDCEMK(gl)R_
MGMT Ubiquitylation K209 0.024 -0.353 _LGK(gl)PGLGGSSGLAGAWLK_
MPST Phosphorylation S15 0.341 _S(ph)PSVAAMASPQLCR_
MPST Phosphorylation S17 1.337 _SPS(ph)VAAMASPQLCR_
MPST Ubiquitylation K166 -1.712 _QNLPLSSGK(gl)SQPAPAEFR_
PTGR1 Ubiquitylation K178 -0.424 _VVGAVGSDEK(gl)VAYLQK_
RPS6KB1 Ubiquitylation K99 -0.316 _VLGK(gl)GGYGK_
RPS6KB1 Phosphorylation S447 -0.525 -0.458 _TPVS(ph)PVKFSPGDFWGR_
SCFD1 Ubiquitylation K126 0.085 _SK(gl)LEDIANAALAASAVTQVAK_
SCFD1 Phosphorylation S297 -0.347 _VNLEES(ph)SGVENSPAGARPK_
SCFD1 Phosphorylation S303 -0.307 -0.139 _VNLEESSGVENS(ph)PAGARPK_
SCFD1 Ubiquitylation K541 -0.462 -0.990 _NLVLK(gl)QQNLPVTR_
SCFD1 Ubiquitylation K642 -0.394 _QLSQLGQK(gl)_
SLC7A11 Ubiquitylation K4 0.814 0.337 _K(gl)PVVSTISK_
SLC7A11 Ubiquitylation K12 0.383 -0.300 _KPVVSTISK(gl)GGYLQGNVNGR_
SLC7A11 Phosphorylation S26 -1.054 -0.909 _LPS(ph)LGNKEPPGQEK_
SLC7A11 Ubiquitylation K30 0.117 -0.427 _LPSLGNK(gl)EPPGQEK_
SLC7A11 Ubiquitylation K222 0.668 _GQTQNFK(gl)DAFSGR_
SLC7A11 Ubiquitylation K483 0.668 _IMSEK(gl)ITR_
SRF Phosphorylation S224 -0.512 -0.458 _ALIQTCLNSPDS(ph)PPR_
TK1 Phosphorylation S13 -1.350 -1.354 _(ac)SCINLPTVLPGS(ph)PSK_
TK1 Phosphorylation S15 -1.567 -1.084 _SCINLPTVLPGSPS(ph)K_
TK1 Ubiquitylation K16 -1.664 _(ac)SCINLPTVLPGSPSK(gl)TR_
TYMS Ubiquitylation K99 -0.992 _GSTNAK(gl)ELSSK_
TYMS Ubiquitylation K104 -0.543 _ELSSK(gl)GVK_
TYMS Ubiquitylation K169 -0.801 -0.836 _VIDTIK(gl)TNPDDRR_
WAPAL Phosphorylation S77 0.020 _VEEESTGDPFGFDS(ph)DDESLPVSSK_
WAPAL Phosphorylation S221 -0.285 -0.043 _RPES(ph)PSEISPIK_
WAPAL Phosphorylation S223 -0.180 0.118 _RPESPS(ph)EISPIK_
WAPAL Phosphorylation S226 -0.473 -0.494 _RPES(ph)PSEIS(ph)PIKGSVR_
WAPAL Phosphorylation S380 -0.868 _S(ph)MDEFTASTPADLGEAGR_


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