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Query: WAPAL

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WAPAL 0 0.754 -0.050 1.110 -0.551 0.359 0.266 -0.378 0.010

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WAPAL Phosphorylation S223 -0.180 0.118 _RPESPS(ph)EISPIK_
WAPAL Phosphorylation S77 0.020 _VEEESTGDPFGFDS(ph)DDESLPVSSK_
WAPAL Phosphorylation S221 -0.285 -0.043 _RPES(ph)PSEISPIK_
WAPAL Phosphorylation S226 -0.473 -0.494 _RPES(ph)PSEIS(ph)PIKGSVR_
WAPAL Phosphorylation S380 -0.868 _S(ph)MDEFTASTPADLGEAGR_

Background Information for WAPAL:





Protein-protein Interactions for WAPAL

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP85L Cat. description Hein, Mann, Cell 2015
Category members IP bait RAD21 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC1A Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait WAPAL Cat. description Hein, Mann, Cell 2015
Category members IP bait AURKA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMTD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DEFA5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJC10 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NDUFA8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PFDN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAD21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SCCPDH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SLCO1B1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST6GAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in WAPAL

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26


Protein complexes (CORUM database) featuring WAPAL

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WAPAL

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0000785 chromatin Database 2.59
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0015630 microtubule cytoskeleton Database 1.34
Category members GO Category GO:0008278 cohesin complex Database 0.44
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0071168 protein localization to chromatin Database 0.04
Category members GO Category GO:0008156 negative regulation of DNA replication Database 0.03
Category members GO Category GO:0000795 synaptonemal complex Database 0
Category members GO Category GO:0009636 response to toxic substance Database 0
Category members GO Category GO:0035562 negative regulation of chromatin binding Database 0
Category members GO Category GO:0045875 negative regulation of sister chromatid cohesion Database 0


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