RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
LIG3	1	-0.380	2.090		-0.284	0.336	0.549	0.370
TOP2B	1	0.830	-0.650	-1.137			0.859	0.666
SMC1B	1	-0.590	0.420	2.703	0.164	0.430	-1.824	0.661
TOP2A	1	-1.940	3.540
TOP2A	1	-1.940	3.540	-1.993			0.211	0.211
SYCP1	1	-1.970	2.940		-0.881
WAPAL	0	-0.050	1.110	-0.551	0.359	0.266	-0.378	0.010
STAG3	0	1.330	-0.580				1.092	0.608
MLH1	0	-0.460	0.110	-0.360	1.227	1.219
UBE2I	0	-0.320	0.480	-0.694			-0.283	0.274
HSPA2	0	-0.890	1.860	0.109
P3H4	0	0.290	-0.450				-1.082	-0.310
INCENP	0						-0.503	-0.357

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
INCENP	Phosphorylation	S72	0.240	0.301	_RIS(ph)YVQDENRDPIR_
INCENP	Phosphorylation	S143		-0.339	_AAAAAAAATMALAAPSS(ph)PT(ph)PESPTMLTK_
INCENP	Phosphorylation	T145		-0.254	_AAAAAAAATMALAAPSS(ph)PT(ph)PESPTMLTK_
INCENP	Phosphorylation	S148		-0.344	_AAAAAAAATMALAAPS(ph)SPTPES(ph)PTMLTK_
INCENP	Phosphorylation	S197	-1.323	-0.719	_TLS(ph)PTPASATAPTSQGIPT(ph)S(ph)DEESTPKK_
INCENP	Phosphorylation	T199	-0.540	-0.981	_TLSPT(ph)PASATAPTSQGIPTSDEESTPK_
INCENP	Phosphorylation	T213	-0.852	-1.444	_TLSPTPASATAPTSQGIPT(ph)SDEESTPK_
INCENP	Phosphorylation	S214	-0.949	-0.913	_TLSPT(ph)PASATAPTSQGIPTS(ph)DEESTPK_
INCENP	Phosphorylation	S218	-0.787	-1.388	_TLSPTPASATAPTSQGIPTSDEES(ph)TPKK_
INCENP	Phosphorylation	T219	-1.593	-1.388	_TLS(ph)PTPASATAPTSQGIPTSDEES(ph)T(ph)PKK_
INCENP	Phosphorylation	S263	0.105	0.492	_IAQVS(ph)PGPR_
INCENP	Phosphorylation	T292	-0.970	-2.284	_VLAPILPDNFST(ph)PTGSR_
INCENP	Phosphorylation	S306	-1.051	-0.736	_TDSQSVRHS(ph)PIAPSSPSPQVLAQK_
INCENP	Phosphorylation	S894		-0.443	_TSS(ph)AVWNSPPLQGAR_
LIG3	Phosphorylation	T209	-0.306	-0.552	_LTTTGQVT(ph)SPVK_
LIG3	Phosphorylation	S210	-0.163	0.011	_LTTTGQVTS(ph)PVK_
LIG3	Phosphorylation	S241	-0.868	-0.902	_PNNSGEAPS(ph)SPTPK_
LIG3	Phosphorylation	S242	-0.782	-0.612	_FSGFSAKPNNSGEAPSS(ph)PTPK_
LIG3	Ubiquitylation	K728	0.493	0.853	_WCTVTK(gl)CAGGHDDATLAR_
LIG3	Ubiquitylation	K833	1.857	0.467	_ELYQLSK(gl)EK_
P3H4	Ubiquitylation	K174		-0.922	_NPK(gl)HELTAK_
P3H4	Ubiquitylation	K213	-1.090	-0.059	_AVK(gl)LYNSGDFR_
SMC1B	Ubiquitylation	K529	-1.309		_K(gl)YQLAVTK_
TOP2A	Phosphorylation	S4	-0.623	-0.424	_(ac)M(ox)EVS(ph)PLQPVNENM(ox)QVNK_
TOP2A	Ubiquitylation	K17	-0.250		_(ac)MEVSPLQPVNENMQVNK(gl)IKK_
TOP2A	Ubiquitylation	K96		0.284	_IFDEILVNAADNK(gl)QR_
TOP2A	Ubiquitylation	K131	0.553	-0.638	_GIPVVEHK(gl)VEK_
TOP2A	Ubiquitylation	K386	-2.203		_ENMTLQPK(gl)SFGSTCQLSEK_
TOP2A	Ubiquitylation	K397	0.214	0.360	_SFGSTCQLSEK(gl)FIK_
TOP2A	Ubiquitylation	K426		-0.502	_AQVQLNKK(gl)_
TOP2A	Ubiquitylation	K489	-0.029	0.171	_GK(gl)ILNVR_
TOP2A	Ubiquitylation	K520		-0.260	_IVGLQYKK(gl)_
TOP2A	Ubiquitylation	K529	0.862	0.065	_NYEDEDSLK(gl)TLR_
TOP2A	Ubiquitylation	K614		-0.287	_YYK(gl)GLGTSTSK_
TOP2A	Ubiquitylation	K622		-0.581	_GLGTSTSK(gl)EAK_
TOP2A	Ubiquitylation	K632	-0.171	-0.248	_EYFADMK(gl)R_
TOP2A	Ubiquitylation	K655	-0.091	-0.407	_YSGPEDDAAISLAFSK(gl)K_
TOP2A	Ubiquitylation	K656	-0.091	-0.441	_YSGPEDDAAISLAFSKK(gl)_
TOP2A	Ubiquitylation	K723		-1.207	_SIPSMVDGLK(gl)PGQR_
TOP2A	Ubiquitylation	K1088		0.061	_GYDSDPVK(gl)AWK_
TOP2A	Phosphorylation	S1142	0.072	0.040	_VPDEEENEES(ph)DNEKETEK_
TOP2A	Ubiquitylation	K1159	-0.411	-0.659	_EQELDTLK(gl)R_
TOP2A	Ubiquitylation	K1199	-0.674	-1.759	_EKQDEQVGLPGKGGK(gl)_
TOP2A	Phosphorylation	S1249	-0.907	-0.546	_TQMAEVLPS(ph)PR_
TOP2A	Phosphorylation	S1283	0.168	0.028	_NENTEGS(ph)PQEDGVELEGLK_
TOP2A	Phosphorylation	S1411	0.232	-0.105	_S(ph)VVSDLEADDVK_
TOP2A	Phosphorylation	S1414	0.884	0.877	_SVVS(ph)DLEADDVK_
TOP2A	Phosphorylation	S1429	-1.415	-2.977	_GSVPLSS(ph)SPPATHFPDETEITNPVPK_
TOP2A	Phosphorylation	S1430		-1.317	_GSVPLSSS(ph)PPATHFPDETEITNPVPK_
TOP2A	Phosphorylation	T1434	-1.348		_GSVPLSSSPPAT(ph)HFPDETEITNPVPK_
TOP2A	Phosphorylation	S1506		-0.384	_RKPS(ph)TSDDSDSNFEK_
TOP2B	Ubiquitylation	K205		0.226	_FTVETACK(gl)EYK_
TOP2B	Ubiquitylation	K221		-0.165	_QTWMNNMMK(gl)TSEAK_
TOP2B	Ubiquitylation	K373		-0.347	_AGVSVK(gl)PFQVK_
TOP2B	Ubiquitylation	K412		-0.274	_SFGSK(gl)CQLSEK_
TOP2B	Ubiquitylation	K550		0.643	_SYDDAESLK(gl)TLR_
TOP2B	Ubiquitylation	K643		-0.133	_GLGTSTAK(gl)EAK_
TOP2B	Ubiquitylation	K646		0.051	_EAK(gl)EYFADMER_
TOP2B	Ubiquitylation	K676		-0.188	_YAGPEDDAAITLAFSK(gl)K_
TOP2B	Ubiquitylation	K677		-0.188	_YAGPEDDAAITLAFSK(gl)K_
TOP2B	Ubiquitylation	K1079		0.700	_FILEK(gl)IQGK_
TOP2B	Ubiquitylation	K1227		-0.462	_K(gl)LQLEETMPSPYGR_
TOP2B	Ubiquitylation	K1250		-0.673	_RIIPEITAM(ox)K(gl)ADASK_
TOP2B	Phosphorylation	S1400	-0.221	-0.192	_VKAS(ph)PITNDGEDEFVPSDGLDKDEYTFSPGK_
TOP2B	Phosphorylation	T1403	-0.017	-0.156	_VKASPIT(ph)NDGEDEFVPSDGLDKDEYTFSPGK_
TOP2B	Phosphorylation	S1413	-0.430	-0.661	_ASPITNDGEDEFVPS(ph)DGLDKDEYTFSPGK_
TOP2B	Phosphorylation	T1422	-0.362		_VKAS(ph)PITNDGEDEFVPSDGLDKDEYT(ph)FSPGK_
TOP2B	Phosphorylation	S1424	-1.672	-1.441	_ASPITNDGEDEFVPSDGLDKDEYTFS(ph)PGK_
TOP2B	Phosphorylation	S1454		1.291	_KSQDFGNLFSFPSYS(ph)QK_
TOP2B	Phosphorylation	S1466	-0.324	-0.202	_FDS(ph)NEEDSASVFSPSFGLK_
TOP2B	Phosphorylation	S1552	2.808		_ASGS(ph)ENEGDYNPGRK_
TOP2B	Phosphorylation	S1581	-0.797	-1.005	_KTSFDQDS(ph)DVDIFPSDFPTEPPSLPR_
UBE2I	Ubiquitylation	K49	0.535		_K(gl)GTPWEGGLFK_
UBE2I	Ubiquitylation	K59	0.481		_GTPWEGGLFK(gl)LR_
WAPAL	Phosphorylation	S77		0.020	_VEEESTGDPFGFDS(ph)DDESLPVSSK_
WAPAL	Phosphorylation	S221	-0.285	-0.043	_RPES(ph)PSEISPIK_
WAPAL	Phosphorylation	S223	-0.180	0.118	_RPESPS(ph)EISPIK_
WAPAL	Phosphorylation	S226	-0.473	-0.494	_RPES(ph)PSEIS(ph)PIKGSVR_
WAPAL	Phosphorylation	S380		-0.868	_S(ph)MDEFTASTPADLGEAGR_