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Query: INCENP

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
INCENP 0 -0.128 -0.503 -0.357

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
INCENP Phosphorylation S263 0.105 0.492 _IAQVS(ph)PGPR_
INCENP Phosphorylation S72 0.240 0.301 _RIS(ph)YVQDENRDPIR_
INCENP Phosphorylation T145 -0.254 _AAAAAAAATMALAAPSS(ph)PT(ph)PESPTMLTK_
INCENP Phosphorylation S143 -0.339 _AAAAAAAATMALAAPSS(ph)PT(ph)PESPTMLTK_
INCENP Phosphorylation S148 -0.344 _AAAAAAAATMALAAPS(ph)SPTPES(ph)PTMLTK_
INCENP Phosphorylation S894 -0.443 _TSS(ph)AVWNSPPLQGAR_
INCENP Phosphorylation S197 -1.323 -0.719 _TLS(ph)PTPASATAPTSQGIPT(ph)S(ph)DEESTPKK_
INCENP Phosphorylation S306 -1.051 -0.736 _TDSQSVRHS(ph)PIAPSSPSPQVLAQK_
INCENP Phosphorylation S214 -0.949 -0.913 _TLSPT(ph)PASATAPTSQGIPTS(ph)DEESTPK_
INCENP Phosphorylation T199 -0.540 -0.981 _TLSPT(ph)PASATAPTSQGIPTSDEESTPK_
INCENP Phosphorylation S218 -0.787 -1.388 _TLSPTPASATAPTSQGIPTSDEES(ph)TPKK_
INCENP Phosphorylation T219 -1.593 -1.388 _TLS(ph)PTPASATAPTSQGIPTSDEES(ph)T(ph)PKK_
INCENP Phosphorylation T213 -0.852 -1.444 _TLSPTPASATAPTSQGIPT(ph)SDEESTPK_
INCENP Phosphorylation T292 -0.970 -2.284 _VLAPILPDNFST(ph)PTGSR_

Background Information for INCENP:


Pubmed-INCENP »
Uniprot-INCENP »
Biogrid-INCENP »
ProteomicsDB-INCENP »

Tumorportal-INCENP »
COSMIC-INCENP »
GenomeRNAi-INCENP »
Genecards-INCENP


Protein-protein Interactions for INCENP
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AURKB Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA8 Cat. description Hein, Mann, Cell 2015
Category members IP bait NFYC Cat. description Hein, Mann, Cell 2015
Category members IP bait PHF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait AURKC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BIRC5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in INCENP
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring INCENP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2579 Chromosomal passenger complex CPC (INCENP, BIRC5, AURKB) Database 0.18
Category members Corum 1087 BIRC5-AURKB-INCENP-EVI5 complex Database 0.05
Category members Corum 1118 Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5, AURKB) Database 0
Category members Corum 1119 Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5, AURKB) Database 0
Category members Corum 1120 Chromosomal passenger complex CPC (INCENP, CDCA8, BIRC5) Database 0


Categories featuring INCENP
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0000278 mitotic cell cycle Database 10.63
Category members Pathway Pathway_321 REACTOME_MITOTIC_M_M_G1_PHASES 0 5.47
Category members Pathway Pathway_323 REACTOME_DNA_REPLICATION 0 5.24
Category members Pathway Pathway_317 REACTOME_CELL_CYCLE_MITOTIC 0 4.82
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0043234 protein complex Database 2.73
Category members Pathway Pathway_726 REACTOME_MITOTIC_PROMETAPHASE 0 2.41
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005874 microtubule Database 1.21
Category members Pathway Pathway_199 PID_BETA_CATENIN_NUC_PATHWAY 0 0.53
Category members Pathway Pathway_911 PID_AURORA_B_PATHWAY 0 0.48
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members GO Category GO:0005721 centromeric heterochromatin Database 0.3
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members Pathway Pathway_1028 PID_PLK1_PATHWAY 0 0.16
Category members GO Category GO:0000910 cytokinesis Database 0.15
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0000795 synaptonemal complex Database 0
Category members GO Category GO:0000800 lateral element Database 0
Category members GO Category GO:0000801 central element Database 0
Category members GO Category GO:0010369 chromocenter Database 0


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