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centromeric heterochromatin
(GO:0005721)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
DNMT1 2 0.150 -0.150 0.077 -0.109 -1.422 0.572
DNMT1 2 0.150 -0.150 0.134 -0.347 -0.054
CBX1 1 -2.050 3.860 -0.630 0.171 1.328 1.100
LRWD1 1 0.490 -0.390 -0.233 0.037 0.364 0.157 0.333
HELLS 0 -1.320 1.650 -1.393 -0.483 -0.069 -0.340 -0.345
CENPC 0 0.220 -0.320 0.525 0.507
INCENP 0 -0.503 -0.357

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CBX1 Ubiquitylation K35 0.698 _GK(gl)VEYLLK_
CBX1 Phosphorylation S89 0.056 0.422 _ADS(ph)DSEDKGEESKPK_
CBX1 Ubiquitylation K139 -0.287 _WK(gl)NSDEADLVPAK_
CBX1 Ubiquitylation K150 0.289 -0.097 _NSDEADLVPAK(gl)EANVK_
CENPC Phosphorylation S73 0.358 0.189 _DTCIQS(ph)PSKECQK_
CENPC Phosphorylation T130 -0.148 _ILATDVSSKNT(ph)PDSK_
CENPC Phosphorylation S333 -0.197 0.504 _TIS(ph)PAESTALFQGR_
CENPC Phosphorylation S538 -0.598 _SEES(ph)PVYSNSSVR_
DNMT1 Phosphorylation S127 -0.755 -0.836 _VGM(ox)ADANS(ph)PPKPLSKPR_
DNMT1 Phosphorylation S143 0.877 0.220 _SKS(ph)DGEAKPEPSPSPR_
DNMT1 Phosphorylation S152 -0.685 -1.347 _SDGEAKPEPS(ph)PSPR_
DNMT1 Phosphorylation S154 -1.926 -0.876 _SDGEAKPEPSPS(ph)PR_
DNMT1 Ubiquitylation K586 1.686 3.368 _DLIK(gl)LAGVTLGQR_
DNMT1 Ubiquitylation K675 1.267 0.915 _DMVK(gl)FGGSGR_
DNMT1 Phosphorylation S714 -0.773 -0.554 _EADDDEEVDDNIPEMPS(ph)PKK_
DNMT1 Phosphorylation S954 -0.318 0.057 _LSS(ph)PVKRPR_
DNMT1 Ubiquitylation K961 -3.166 _K(gl)EPVDEDLYPEHYR_
DNMT1 Ubiquitylation K981 -0.298 -1.482 _YSDYIK(gl)GSNLDAPEPYR_
DNMT1 Ubiquitylation K997 0.042 0.154 _IK(gl)EIFCPK_
DNMT1 Ubiquitylation K1483 1.983 -0.103 _GVCSCVEAGK(gl)ACDPAAR_
HELLS Ubiquitylation K74 0.655 _LQHLLEK(gl)SNIYSK_
HELLS Phosphorylation S115 0.257 _NS(ph)IDASEEKPVMR_
HELLS Ubiquitylation K474 -0.723 _EVVVYAPLSK(gl)K_
HELLS Ubiquitylation K475 -0.723 _EVVVYAPLSK(gl)K_
HELLS Ubiquitylation K753 0.741 _NHFK(gl)GGQSGLNLSK_
HELLS Ubiquitylation K776 0.359 _ELMELLK(gl)SR_
INCENP Phosphorylation S72 0.240 0.301 _RIS(ph)YVQDENRDPIR_
INCENP Phosphorylation S143 -0.339 _AAAAAAAATMALAAPSS(ph)PT(ph)PESPTMLTK_
INCENP Phosphorylation T145 -0.254 _AAAAAAAATMALAAPSS(ph)PT(ph)PESPTMLTK_
INCENP Phosphorylation S148 -0.344 _AAAAAAAATMALAAPS(ph)SPTPES(ph)PTMLTK_
INCENP Phosphorylation S197 -1.323 -0.719 _TLS(ph)PTPASATAPTSQGIPT(ph)S(ph)DEESTPKK_
INCENP Phosphorylation T199 -0.540 -0.981 _TLSPT(ph)PASATAPTSQGIPTSDEESTPK_
INCENP Phosphorylation T213 -0.852 -1.444 _TLSPTPASATAPTSQGIPT(ph)SDEESTPK_
INCENP Phosphorylation S214 -0.949 -0.913 _TLSPT(ph)PASATAPTSQGIPTS(ph)DEESTPK_
INCENP Phosphorylation S218 -0.787 -1.388 _TLSPTPASATAPTSQGIPTSDEES(ph)TPKK_
INCENP Phosphorylation T219 -1.593 -1.388 _TLS(ph)PTPASATAPTSQGIPTSDEES(ph)T(ph)PKK_
INCENP Phosphorylation S263 0.105 0.492 _IAQVS(ph)PGPR_
INCENP Phosphorylation T292 -0.970 -2.284 _VLAPILPDNFST(ph)PTGSR_
INCENP Phosphorylation S306 -1.051 -0.736 _TDSQSVRHS(ph)PIAPSSPSPQVLAQK_
INCENP Phosphorylation S894 -0.443 _TSS(ph)AVWNSPPLQGAR_
LRWD1 Ubiquitylation K171 0.407 -0.643 _AQADFVK(gl)SAVR_
LRWD1 Phosphorylation S212 -0.942 -0.704 _ANS(ph)PEKPPEAGAAHKPR_
LRWD1 Phosphorylation S243 -0.579 -0.857 _RPDDVPLSLS(ph)PSK_
LRWD1 Phosphorylation S245 2.408 _RPDDVPLSLSPS(ph)KR_
LRWD1 Phosphorylation S251 -0.242 -0.453 _ACAS(ph)PSAQVEGS(ph)PVAGSDGSQPAVK_
LRWD1 Phosphorylation S259 -0.749 0.053 _ACAS(ph)PSAQVEGS(ph)PVAGSDGSQPAVK_


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