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Query: LRWD1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
LRWD1 1 2.587 0.490 -0.390 -0.233 0.037 0.364 0.157 0.333

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
LRWD1 Phosphorylation S245 2.408 _RPDDVPLSLSPS(ph)KR_
LRWD1 Phosphorylation S259 -0.749 0.053 _ACAS(ph)PSAQVEGS(ph)PVAGSDGSQPAVK_
LRWD1 Phosphorylation S251 -0.242 -0.453 _ACAS(ph)PSAQVEGS(ph)PVAGSDGSQPAVK_
LRWD1 Ubiquitylation K171 0.407 -0.643 _AQADFVK(gl)SAVR_
LRWD1 Phosphorylation S212 -0.942 -0.704 _ANS(ph)PEKPPEAGAAHKPR_
LRWD1 Phosphorylation S243 -0.579 -0.857 _RPDDVPLSLS(ph)PSK_

Background Information for LRWD1:


Pubmed-LRWD1 »
Uniprot-LRWD1 »
Biogrid-LRWD1 »
ProteomicsDB-LRWD1 »

Tumorportal-LRWD1 »
COSMIC-LRWD1 »
GenomeRNAi-LRWD1 »
Genecards-LRWD1


Protein-protein Interactions for LRWD1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LRWD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MPHOSPH8 Cat. description Hein, Mann, Cell 2015
Category members IP bait ORC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ORC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait DNAJC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OBFC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ORC6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RNF126 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPGR Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in LRWD1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members Leu-rich_rpt_typical-subtyp IPR003591 0.57
Category members WD40_repeat IPR001680 0.52
Category members Leu-rich_rpt IPR001611 0.32


Protein complexes (CORUM database) featuring LRWD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring LRWD1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006325 chromatin organization Database 5.02
Category members GO Category GO:0006270 DNA replication initiation Database 0.57
Category members GO Category GO:0035064 methylated histone residue binding Database 0.53
Category members GO Category GO:0008327 methyl-CpG binding Database 0.52
Category members GO Category GO:0005815 microtubule organizing center Database 0.39
Category members GO Category GO:0005721 centromeric heterochromatin Database 0.3
Category members GO Category GO:0016568 chromatin modification Database 0.18
Category members GO Category GO:0005664 nuclear origin of replication recognition complex Database 0
Category members GO Category GO:0071169 establishment of protein localization to chromatin Database 0


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