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Query: CBX1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CBX1 1 6.908 -2.050 3.860 -0.630 0.171 1.328 1.100

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
CBX1 Phosphorylation S89 0.056 0.422 _ADS(ph)DSEDKGEESKPK_
CBX1 Ubiquitylation K150 0.289 -0.097 _NSDEADLVPAK(gl)EANVK_
CBX1 Ubiquitylation K35 0.698 _GK(gl)VEYLLK_
CBX1 Ubiquitylation K139 -0.287 _WK(gl)NSDEADLVPAK_

Background Information for CBX1:


Pubmed-CBX1 »
Uniprot-CBX1 »
Biogrid-CBX1 »
ProteomicsDB-CBX1 »

Tumorportal-CBX1 »
COSMIC-CBX1 »
GenomeRNAi-CBX1 »
Genecards-CBX1


Protein-protein Interactions for CBX1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHAMP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAD2L2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAU2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait PCGF6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRR14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SUV39H2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRIM28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CBX1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Chromo_domain/shadow IPR000953 2.84
Category members Chromodomain-like IPR016197 2.29
Category members Chromo_domain IPR023780 1.98
Category members Chromo_dom_subgr IPR017984 0.83
Category members Chromo_shadow_dom IPR008251 0.46


Protein complexes (CORUM database) featuring CBX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CBX1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0000785 chromatin Database 2.59
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0005720 nuclear heterochromatin Database 1.41
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0005819 spindle Database 0.41
Category members GO Category GO:0005721 centromeric heterochromatin Database 0.3
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0001939 female pronucleus Database 0
Category members GO Category GO:0001940 male pronucleus Database 0
Category members GO Category GO:0010369 chromocenter Database 0


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