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Query: SMC1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SMC1B 1 1.245 -0.590 0.420 2.703 0.164 0.430 -1.824 0.661

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SMC1B Ubiquitylation K529 -1.309 _K(gl)YQLAVTK_

Background Information for SMC1B:


Pubmed-SMC1B »
Uniprot-SMC1B »
Biogrid-SMC1B »
ProteomicsDB-SMC1B »

Tumorportal-SMC1B »
COSMIC-SMC1B »
GenomeRNAi-SMC1B »
Genecards-SMC1B


Protein-protein Interactions for SMC1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait RAD21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SMC1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members t-SNARE IPR010989 0.04
Category members RecF/RecN/SMC_N IPR003395 0
Category members SMC_hinge IPR010935 0


Protein complexes (CORUM database) featuring SMC1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SMC1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members Pathway Pathway_884 REACTOME_MEIOTIC_SYNAPSIS 0 7.46
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members Pathway Pathway_223 KEGG_OOCYTE_MEIOSIS 0 2.71
Category members Pathway Pathway_866 KEGG_CELL_CYCLE 0 2.13
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0016192 vesicle-mediated transport Database 1.1
Category members GO Category GO:0007062 sister chromatid cohesion Database 0.69
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0000775 chromosome, centromeric region Database 0.29
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0030893 meiotic cohesin complex Database 0.22
Category members GO Category GO:0034991 nuclear meiotic cohesin complex Database 0.11
Category members GO Category GO:0051276 chromosome organization Database 0.1
Category members GO Category GO:0007064 mitotic sister chromatid cohesion Database 0.03
Category members GO Category GO:0007126 meiosis Database 0.01
Category members GO Category GO:0000795 synaptonemal complex Database 0
Category members GO Category GO:0000800 lateral element Database 0


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