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Query: UBE2I

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBE2I 0 0.312 -0.320 0.480 -0.694 -0.283 0.274

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBE2I Ubiquitylation K49 0.535 _K(gl)GTPWEGGLFK_
UBE2I Ubiquitylation K59 0.481 _GTPWEGGLFK(gl)LR_

Background Information for UBE2I:


Pubmed-UBE2I »
Uniprot-UBE2I »
Biogrid-UBE2I »
ProteomicsDB-UBE2I »

Tumorportal-UBE2I »
COSMIC-UBE2I »
GenomeRNAi-UBE2I »
Genecards-UBE2I


Protein-protein Interactions for UBE2I
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KPNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP107 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP153 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait RANBP2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RCC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TRIM32 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBE2I Cat. description Hein, Mann, Cell 2015
Category members IP bait B2M Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM194A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBE2I
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBQ-conjugat_E2 IPR000608 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring UBE2I
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 3634 NR3C2-UBC9-SRC-1 complex Database 0


Categories featuring UBE2I
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members Pathway Pathway_884 REACTOME_MEIOTIC_SYNAPSIS 0 7.46
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0007067 mitosis Database 2.23
Category members Pathway Pathway_888 KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 0 2.22
Category members GO Category GO:0019899 enzyme binding Database 1.57
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0016605 PML body Database 1.41
Category members Pathway Pathway_1254 PID_RANBP2_PATHWAY 0 1.33
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members Pathway Pathway_943 PID_HDAC_CLASSI_PATHWAY 0 1.08
Category members Pathway Pathway_880 PID_AR_PATHWAY 0 0.58
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0016925 protein sumoylation Database 0.33
Category members Pathway Pathway_1143 PID_HDAC_CLASSII_PATHWAY 0 0.3
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members Pathway Pathway_210 PID_CMYB_PATHWAY 0 0.2
Category members GO Category GO:0007059 chromosome segregation Database 0.13
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0019789 SUMO ligase activity Database 0.05
Category members Pathway Pathway_1131 PID_SMAD2_3PATHWAY 0 0.04
Category members GO Category GO:0016604 nuclear body Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0000795 synaptonemal complex Database 0
Category members GO Category GO:0006464 cellular protein modification process Database 0
Category members GO Category GO:0010469 regulation of receptor activity Database 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0
Category members GO Category GO:0043398 HLH domain binding Database 0
Category members GO Category GO:0043425 bHLH transcription factor binding Database 0
Category members GO Category GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity Database 0


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