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Query: SLC7A11

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SLC7A11 0 0.999 -0.760 1.480

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SLC7A11 Ubiquitylation K222 0.668 _GQTQNFK(gl)DAFSGR_
SLC7A11 Ubiquitylation K483 0.668 _IMSEK(gl)ITR_
SLC7A11 Ubiquitylation K4 0.814 0.337 _K(gl)PVVSTISK_
SLC7A11 Ubiquitylation K12 0.383 -0.300 _KPVVSTISK(gl)GGYLQGNVNGR_
SLC7A11 Ubiquitylation K30 0.117 -0.427 _LPSLGNK(gl)EPPGQEK_
SLC7A11 Phosphorylation S26 -1.054 -0.909 _LPS(ph)LGNKEPPGQEK_

Background Information for SLC7A11:


Pubmed-SLC7A11 »
Uniprot-SLC7A11 »
Biogrid-SLC7A11 »
ProteomicsDB-SLC7A11 »

Tumorportal-SLC7A11 »
COSMIC-SLC7A11 »
GenomeRNAi-SLC7A11 »
Genecards-SLC7A11


Protein-protein Interactions for SLC7A11
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in SLC7A11
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members AA-permease/SLC12A_dom IPR004841 0.08
Category members AA/rel_permease1 IPR002293 0
Category members L_AA_transporter IPR004760 0
Category members AA_transpt_TM IPR013057 0


Protein complexes (CORUM database) featuring SLC7A11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SLC7A11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_1307 REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE 0 0.32
Category members Pathway Pathway_96 REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 0 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0070306 lens fiber cell differentiation Database 0.13
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_1271 REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS 0 0.11
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members Pathway Pathway_600 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL 0 0.05
Category members GO Category GO:0070527 platelet aggregation Database 0.05
Category members GO Category GO:0050900 leukocyte migration Database 0.04
Category members Pathway Pathway_927 REACTOME_BASIGIN_INTERACTIONS 0 0
Category members Pathway Pathway_1207 REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 0 0
Category members GO Category GO:0003333 amino acid transmembrane transport Database 0
Category members GO Category GO:0005791 rough endoplasmic reticulum Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0006865 amino acid transport Database 0
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0007420 brain development Database 0
Category members GO Category GO:0009636 response to toxic substance Database 0
Category members GO Category GO:0015171 amino acid transmembrane transporter activity Database 0
Category members GO Category GO:0035094 response to nicotine Database 0


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