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lens fiber cell differentiation
(GO:0070306)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
FZR1 0 0.740 -0.470
TGFB1 0 -0.550 1.050
SLC7A11 0 -0.760 1.480
SMAD3 0 -1.560 1.800
SMAD3 0 0.270 -0.340
NF2 0 -1.080 1.470 0.218 -0.073
NF2 0 -1.080 1.470
TDRD7 0 -0.390 1.130

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
FZR1 Ubiquitylation K135 -0.177 _GLFTYSLSTK(gl)R_
FZR1 Ubiquitylation K263 0.187 _GFVQIWDAAAGKK(gl)_
NF2 Phosphorylation S13 0.833 0.924 _MSFSS(ph)LKR_
NF2 Phosphorylation S493 1.436 1.115 _RLS(ph)MEIEK_
NF2 Ubiquitylation K586 0.399 -0.041 _LTLQSAK(gl)SR_
SLC7A11 Ubiquitylation K4 0.814 0.337 _K(gl)PVVSTISK_
SLC7A11 Ubiquitylation K12 0.383 -0.300 _KPVVSTISK(gl)GGYLQGNVNGR_
SLC7A11 Phosphorylation S26 -1.054 -0.909 _LPS(ph)LGNKEPPGQEK_
SLC7A11 Ubiquitylation K30 0.117 -0.427 _LPSLGNK(gl)EPPGQEK_
SLC7A11 Ubiquitylation K222 0.668 _GQTQNFK(gl)DAFSGR_
SLC7A11 Ubiquitylation K483 0.668 _IMSEK(gl)ITR_
SMAD3 Ubiquitylation K13 -0.704 _(ac)SSILPFTPPIVK(gl)R_
TDRD7 Ubiquitylation K576 0.029 1.028 _FCSLSFQATK(gl)CK_
TGFB1 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_


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