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Query: GABRB1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GABRB1 0 0.445 0.040 -0.270

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GABRB1 Ubiquitylation K193 0.445 _SFVHGVTVK(gl)NR_

Background Information for GABRB1:


Pubmed-GABRB1 »
Uniprot-GABRB1 »
Biogrid-GABRB1 »
ProteomicsDB-GABRB1 »

Tumorportal-GABRB1 »
COSMIC-GABRB1 »
GenomeRNAi-GABRB1 »
Genecards-GABRB1


Protein-protein Interactions for GABRB1
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in GABRB1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Neurotrans-gated_channel_TM IPR006029 0.09
Category members Neur_chan_lig-bd IPR006202 0.09
Category members Neur_channel IPR006201 0.08
Category members GABBAg_rcpt IPR005437 0.05
Category members GABAA/Glycine_rcpt IPR006028 0.04
Category members GABAAb_rcpt IPR002289 0


Protein complexes (CORUM database) featuring GABRB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GABRB1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0005635 nuclear envelope Database 7.22
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members Pathway Pathway_1184 KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 0 1.89
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members GO Category GO:0032570 response to progesterone Database 0.1
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members Pathway Pathway_1242 REACTOME_GABA_A_RECEPTOR_ACTIVATION 0 0.05
Category members GO Category GO:0005253 anion channel activity Database 0.05
Category members GO Category GO:0043235 receptor complex Database 0.04
Category members GO Category GO:0021954 central nervous system neuron development Database 0.02
Category members Pathway Pathway_1243 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT 0 0.02
Category members GO Category GO:0005230 extracellular ligand-gated ion channel activity Database 0
Category members GO Category GO:0034707 chloride channel complex Database 0
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_183 REACTOME_ION_CHANNEL_TRANSPORT 0 0
Category members Pathway Pathway_215 REACTOME_GABA_RECEPTOR_ACTIVATION 0 0
Category members Pathway Pathway_230 REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 0 0
Category members GO Category GO:0004890 GABA-A receptor activity Database 0
Category members GO Category GO:0005254 chloride channel activity Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0009636 response to toxic substance Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0034220 ion transmembrane transport Database 0
Category members GO Category GO:0042698 ovulation cycle Database 0
Category members GO Category GO:0050811 GABA receptor binding Database 0


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