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Query: UIMC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UIMC1 3 7.931 -1.570 2.710 0.307 -0.624

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UIMC1 Phosphorylation S140 2.351 _SRPLATGPSS(ph)QSHQEK_
UIMC1 Phosphorylation S101 2.729 2.276 _EVNS(ph)QEEEEEELLRK_
UIMC1 Phosphorylation S654 0.098 0.120 _VPS(ph)PGM(ox)EEAGCSR_
UIMC1 Ubiquitylation K31 0.443 0.015 _KDVETTSSVSVK(gl)R_
UIMC1 Ubiquitylation K245 0.435 0.000 _GSAFLK(gl)AVQGSGDTSR_
UIMC1 Ubiquitylation K20 -0.247 -0.187 _K(gl)DVETTSSVSVK_
UIMC1 Phosphorylation S678 0.108 -0.289 _RDLNES(ph)PVK_
UIMC1 Ubiquitylation K568 -1.100 -0.475 _CYLCK(gl)SLVPFR_
UIMC1 Ubiquitylation K608 0.301 -0.587 _ACSTVEGK(gl)WQQR_
UIMC1 Ubiquitylation K382 0.111 -0.591 _TKDFQESSIK(gl)SLK_
UIMC1 Ubiquitylation K545 -0.089 -0.679 _TK(gl)SDSGTAAQTSLDIDKNEK_
UIMC1 Ubiquitylation K19 -0.178 -1.011 _NLEK(gl)KDVETTSSVSVK_
UIMC1 Ubiquitylation K374 -0.119 -1.262 _TK(gl)DFQESSIK_

Background Information for UIMC1:


Pubmed-UIMC1 »
Uniprot-UIMC1 »
Biogrid-UIMC1 »
ProteomicsDB-UIMC1 »

Tumorportal-UIMC1 »
COSMIC-UIMC1 »
GenomeRNAi-UIMC1 »
Genecards-UIMC1


Protein-protein Interactions for UIMC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait JUNB Cat. description Hein, Mann, Cell 2015
Category members IP bait BABAM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C18orf1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COMMD8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UIMC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UIMC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-int_motif IPR003903 0.49


Protein complexes (CORUM database) featuring UIMC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2786 BRCA1 A complex Database 0.68
Category members Corum 2787 BRCA1 C complex Database 0.66


Categories featuring UIMC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members Pathway Pathway_978 PID_ATM_PATHWAY 0 4.31
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0070530 K63-linked polyubiquitin binding Database 0.35
Category members GO Category GO:0070537 histone H2A K63-linked deubiquitination Database 0.11
Category members GO Category GO:0070531 BRCA1-A complex Database 0.04
Category members GO Category GO:0045739 positive regulation of DNA repair Database 0.04
Category members GO Category GO:0031572 G2 DNA damage checkpoint Database 0
Category members GO Category GO:0046965 retinoid X receptor binding Database 0


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