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Query: UBE2V2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBE2V2 0 1.269 -0.070 0.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBE2V2 Ubiquitylation K129 0.440 0.709 _LMMSK(gl)ENMK_
UBE2V2 Ubiquitylation K8 -0.337 -0.243 _(ac)AVSTGVK(gl)VPR_
UBE2V2 Ubiquitylation K72 -0.575 -0.545 _VECGPK(gl)YPEAPPSVR_
UBE2V2 Ubiquitylation K66 -0.608 _IYSLK(gl)VECGPK_

Background Information for UBE2V2:


Pubmed-UBE2V2 »
Uniprot-UBE2V2 »
Biogrid-UBE2V2 »
ProteomicsDB-UBE2V2 »

Tumorportal-UBE2V2 »
COSMIC-UBE2V2 »
GenomeRNAi-UBE2V2 »
Genecards-UBE2V2


Protein-protein Interactions for UBE2V2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C20orf43;RTFDC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLK Cat. description Hein, Mann, Cell 2015
Category members IP bait RHOA Cat. description Hein, Mann, Cell 2015
Category members IP bait TIGD6 Cat. description Hein, Mann, Cell 2015


Protein Domains in UBE2V2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UBQ-conjugat_E2 IPR000608 0
Category members UBQ-conjugating_enzyme/RWD IPR016135 0


Protein complexes (CORUM database) featuring UBE2V2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2756 Ubiquitin-protein-ligase (UBE2N, UBE2V2/MMS2) Database 0.22


Categories featuring UBE2V2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members GO Category GO:0000209 protein polyubiquitination Database 2.46
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process Database 0.24
Category members GO Category GO:0031372 UBC13-MMS2 complex Database 0.22
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0008283 cell proliferation Database 0.06
Category members GO Category GO:0010976 positive regulation of neuron projection development Database 0.05
Category members GO Category GO:0045739 positive regulation of DNA repair Database 0.04
Category members GO Category GO:0000729 DNA double-strand break processing Database 0
Category members GO Category GO:0006282 regulation of DNA repair Database 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0
Category members GO Category GO:0051965 positive regulation of synapse assembly Database 0


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