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Query: RNF8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
RNF8 0 -0.815 1.030 -0.670

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
RNF8 Phosphorylation S157 -0.377 -0.438 _KFS(ph)LDELAGPGAEGPSNLK_

Background Information for RNF8:


Pubmed-RNF8 »
Uniprot-RNF8 »
Biogrid-RNF8 »
ProteomicsDB-RNF8 »

Tumorportal-RNF8 »
COSMIC-RNF8 »
GenomeRNAi-RNF8 »
Genecards-RNF8


Protein-protein Interactions for RNF8
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in RNF8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members FHA_dom IPR000253 2.3
Category members SMAD_FHA_domain IPR008984 0.86
Category members Znf_RING IPR001841 0
Category members Znf_C3HC4_RING-type IPR018957 0


Protein complexes (CORUM database) featuring RNF8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring RNF8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006302 double-strand break repair Database 4.62
Category members Pathway Pathway_978 PID_ATM_PATHWAY 0 4.31
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0031625 ubiquitin protein ligase binding Database 2.54
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0051301 cell division Database 1.15
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0006303 double-strand break repair via nonhomologous end joining Database 0.79
Category members GO Category GO:0033523 histone H2B ubiquitination Database 0.77
Category members GO Category GO:0035861 site of double-strand break Database 0.65
Category members GO Category GO:0030496 midbody Database 0.39
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0051865 protein autoubiquitination Database 0.18
Category members GO Category GO:0000781 chromosome, telomeric region Database 0.16
Category members GO Category GO:0045190 isotype switching Database 0.11
Category members GO Category GO:0016567 protein ubiquitination Database 0.07
Category members GO Category GO:0045739 positive regulation of DNA repair Database 0.04
Category members GO Category GO:0007286 spermatid development Database 0
Category members GO Category GO:0016881 acid-amino acid ligase activity Database 0
Category members GO Category GO:0033522 histone H2A ubiquitination Database 0
Category members GO Category GO:0036297 interstrand cross-link repair Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0043486 histone exchange Database 0
Category members GO Category GO:0045900 negative regulation of translational elongation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0070534 protein K63-linked ubiquitination Database 0
Category members GO Category GO:0070535 histone H2A K63-linked ubiquitination Database 0
Category members GO Category GO:0070936 protein K48-linked ubiquitination Database 0


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