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Results for the Category
double-strand break repair via nonhomologous end joining
(GO:0006303)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
PRKDC 3 1.430 -1.280 -0.994 -0.672 -0.244 0.307 0.443
LIG3 1 -0.380 2.090 -0.284 0.336 0.549 0.370
XRCC4 1 -0.240 0.070
MRE11A 0 1.600 -0.730 0.145 0.420
MRE11A 0 1.600 -0.730 0.023 0.453 0.150
MLH1 0 -0.460 0.110 -0.360 1.227 1.219
XRCC5 0 1.940 -0.800 0.205 -0.587 0.234 -0.176 0.162
POLA1 0 0.720 -0.610 0.594 0.355 0.027
LIG1 0 0.370 -0.580
RNF8 0 1.030 -0.670
PSMD14 0 -0.108 -0.655 0.117 -0.121 -0.010
XRCC6 0 0.960 -0.800
XRCC6 0 0.960 -0.800 -0.089 -0.758 0.145 0.033 0.140

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
LIG1 Phosphorylation S49 0.101 _EWNGVVSES(ph)DSPVK_
LIG1 Phosphorylation S51 0.145 -0.066 _EWNGVVSESDS(ph)PVK_
LIG1 Phosphorylation S66 0.671 0.408 _VLGS(ph)EGEEEDEALSPAK_
LIG1 Phosphorylation S76 -0.083 0.108 _VLGSEGEEEDEALS(ph)PAK_
LIG1 Phosphorylation S88 1.273 _GQKPALDCS(ph)QVSPPRPATSPENNASLSDTSPMDSSPSGIPK_
LIG1 Phosphorylation S141 0.697 0.877 _TIQEVLEEQS(ph)EDEDREAK_
LIG1 Phosphorylation T182 -0.768 -0.709 _EGEDGDQPT(ph)TPPKPLK_
LIG1 Phosphorylation T183 -0.923 -0.825 _EGEDGDQPTT(ph)PPKPLK_
LIG1 Phosphorylation T195 0.021 0.224 _AET(ph)PTESVS(ph)EPEVATK_
LIG1 Phosphorylation T197 0.441 0.125 _AETPT(ph)ESVSEPEVATK_
LIG1 Phosphorylation S199 0.721 _AET(ph)PTES(ph)VSEPEVATK_
LIG1 Phosphorylation S201 -0.213 0.070 _AET(ph)PTESVS(ph)EPEVATK_
LIG3 Phosphorylation T209 -0.306 -0.552 _LTTTGQVT(ph)SPVK_
LIG3 Phosphorylation S210 -0.163 0.011 _LTTTGQVTS(ph)PVK_
LIG3 Phosphorylation S241 -0.868 -0.902 _PNNSGEAPS(ph)SPTPK_
LIG3 Phosphorylation S242 -0.782 -0.612 _FSGFSAKPNNSGEAPSS(ph)PTPK_
LIG3 Ubiquitylation K728 0.493 0.853 _WCTVTK(gl)CAGGHDDATLAR_
LIG3 Ubiquitylation K833 1.857 0.467 _ELYQLSK(gl)EK_
MRE11A Ubiquitylation K387 0.442 _FSQK(gl)FVDR_
POLA1 Phosphorylation S192 -0.049 -0.187 _S(ph)IGASPNPFSVHTATAVPSGK_
POLA1 Phosphorylation S196 -0.374 _RSIGAS(ph)PNPFSVHTATAVPSGK_
POLA1 Ubiquitylation K1120 -0.317 _DTIVENIQK(gl)R_
PRKDC Ubiquitylation K108 0.568 -0.049 _IAPYSVEIK(gl)NTCTSVYTK_
PRKDC Ubiquitylation K117 0.540 0.376 _NTCTSVYTK(gl)DR_
PRKDC Ubiquitylation K163 0.679 _FYGELALK(gl)K_
PRKDC Ubiquitylation K164 -0.371 _FYGELALKK(gl)_
PRKDC Ubiquitylation K263 0.272 -0.659 _AIRPQIDLK(gl)R_
PRKDC Ubiquitylation K357 1.479 _NVDSNNK(gl)ELSIAIR_
PRKDC Ubiquitylation K374 -0.342 _GYGLFAGPCK(gl)VINAK_
PRKDC Ubiquitylation K493 -0.582 _ICSK(gl)PVVLPK_
PRKDC Ubiquitylation K689 -0.187 _YFEGVSPK(gl)SLK_
PRKDC Ubiquitylation K810 0.561 0.360 _TSALSDETK(gl)NNWEVSALSR_
PRKDC Ubiquitylation K828 0.723 -0.203 _GFNK(gl)VVLK_
PRKDC Ubiquitylation K832 1.611 -0.278 _VVLK(gl)HLK_
PRKDC Ubiquitylation K838 1.939 1.087 _TK(gl)NLSSNEAISLEEIR_
PRKDC Ubiquitylation K963 -1.201 _ATQMPEGGQGAPPMYQLYK(gl)R_
PRKDC Ubiquitylation K1038 0.646 _EFLK(gl)WSIK_
PRKDC Ubiquitylation K1042 -0.070 -0.432 _WSIK(gl)QITPQQQEK_
PRKDC Ubiquitylation K1051 -1.153 _QITPQQQEK(gl)SPVNTK_
PRKDC Ubiquitylation K1057 -0.693 _SPVNTK(gl)SLFK_
PRKDC Ubiquitylation K1334 0.108 _YNYSK(gl)CTVVVR_
PRKDC Ubiquitylation K1407 -0.971 _ALK(gl)MSPYK_
PRKDC Ubiquitylation K1456 0.657 -0.495 _LAAVVSACK(gl)QLHR_
PRKDC Ubiquitylation K1744 -0.269 _FNNYVDCMK(gl)K_
PRKDC Ubiquitylation K1857 -0.152 _FTK(gl)LNESTFDTQITK_
PRKDC Ubiquitylation K1869 0.803 _LNESTFDTQITK(gl)K_
PRKDC Ubiquitylation K1870 0.843 -0.566 _LNESTFDTQITKK(gl)_
PRKDC Ubiquitylation K1892 -1.132 -1.666 _LPKDDVHAK(gl)ESK_
PRKDC Ubiquitylation K2418 -0.499 _SK(gl)DFVQVMR_
PRKDC Ubiquitylation K2447 -0.500 -1.069 _LK(gl)PVELR_
PRKDC Phosphorylation S2612 -0.226 1.740 _STVLTPMFVETQAS(ph)QGTLQTR_
PRKDC Phosphorylation T2671 -0.097 _SSFDWLTGSSTDPLVDHT(ph)SPSSDSLLFAHK_
PRKDC Phosphorylation S2672 0.083 _SSFDWLTGSSTDPLVDHTS(ph)PSSDSLLFAHK_
PRKDC Phosphorylation S2675 -0.193 _SSFDWLTGSSTDPLVDHTSPSS(ph)DSLLFAHK_
PRKDC Phosphorylation S2677 0.284 -0.009 _SSFDWLTGSSTDPLVDHTSPSSDS(ph)LLFAHK_
PRKDC Ubiquitylation K2694 -1.865 _APLK(gl)SVGPDFGKK_
PRKDC Ubiquitylation K2703 0.600 _SVGPDFGKK(gl)_
PRKDC Ubiquitylation K2715 0.258 -1.356 _LGLPGDEVDNK(gl)VK_
PRKDC Ubiquitylation K2717 -1.795 _LGLPGDEVDNKVK(gl)GAAGR_
PRKDC Ubiquitylation K2738 -0.251 -0.421 _DQEK(gl)LSLMYAR_
PRKDC Ubiquitylation K2758 -0.370 _EKEIK(gl)SELK_
PRKDC Ubiquitylation K2764 0.293 -0.445 _MK(gl)QDAQVVLYR_
PRKDC Ubiquitylation K2829 -1.122 _TLSEK(gl)NNITQK_
PRKDC Ubiquitylation K2908 -0.765 -1.790 _LLPAELPAK(gl)R_
PRKDC Ubiquitylation K2928 0.416 -0.319 _WVELAK(gl)LYR_
PRKDC Ubiquitylation K3158 0.005 -1.352 _QGNLSSQVPLK(gl)R_
PRKDC Ubiquitylation K3192 -0.192 _CFFLSK(gl)IEEK_
PRKDC Phosphorylation S3205 2.096 1.572 _LTPLPEDNS(ph)M(ox)NVDQDGDPSDR_
PRKDC Ubiquitylation K3235 0.810 0.153 _SCK(gl)FSMK_
PRKDC Ubiquitylation K3241 0.107 -0.523 _MK(gl)MIDSAR_
PRKDC Ubiquitylation K3248 0.977 -0.289 _K(gl)QNNFSLAMK_
PRKDC Ubiquitylation K3260 0.018 -1.258 _LLK(gl)ELHK_
PRKDC Ubiquitylation K3455 0.488 -0.615 _ALK(gl)LNSNEAR_
PRKDC Ubiquitylation K3552 1.164 0.277 _NK(gl)EFVAR_
PRKDC Ubiquitylation K3608 1.045 1.399 _NIEK(gl)MYER_
PRKDC Ubiquitylation K3631 -1.002 _K(gl)FIQTFGK_
PRKDC Ubiquitylation K3650 0.475 -0.515 _GGSK(gl)LLR_
PRKDC Ubiquitylation K3710 0.119 -0.965 _GK(gl)PLPEYHVR_
PRKDC Ubiquitylation K3877 0.018 -2.000 _ESK(gl)VPADLLKR_
PRKDC Ubiquitylation K3884 -0.255 -1.203 _VPADLLK(gl)R_
PRKDC Ubiquitylation K4019 -0.937 _NFEQK(gl)MLK_
PRKDC Ubiquitylation K4023 -0.481 _K(gl)GGSWIQEINVAEK_
PSMD14 Ubiquitylation K154 -1.127 0.434 _GK(gl)VVIDAFR_
PSMD14 Ubiquitylation K253 0.194 -0.255 _EMLELAK(gl)NYNK_
PSMD14 Ubiquitylation K257 -0.581 -0.994 _NYNK(gl)AVEEEDKMTPEQLAIK_
RNF8 Phosphorylation S157 -0.377 -0.438 _KFS(ph)LDELAGPGAEGPSNLK_
XRCC4 Ubiquitylation K178 0.552 _EALETDLYK(gl)R_
XRCC4 Ubiquitylation K197 0.264 _SLHNK(gl)LLNAAQER_
XRCC4 Phosphorylation S259 -0.552 1.634 _DDSIIS(ph)SLDVTDIAPSR_
XRCC4 Phosphorylation S260 -0.545 1.299 _DDSIISS(ph)LDVTDIAPSR_
XRCC4 Phosphorylation S320 0.439 1.683 _KEHISAENM(ox)S(ph)LETLR_
XRCC5 Ubiquitylation K195 -0.495 -0.075 _LGGHGPSFPLK(gl)GITEQQK_
XRCC5 Ubiquitylation K265 -0.577 0.489 _IAAYK(gl)SILQER_
XRCC5 Ubiquitylation K282 0.763 _TWTVVDAK(gl)TLKK_
XRCC5 Ubiquitylation K325 0.022 -0.122 _YGSDIVPFSK(gl)VDEEQMK_
XRCC5 Ubiquitylation K332 -0.032 0.491 _VDEEQMK(gl)YK_
XRCC5 Ubiquitylation K347 0.588 1.044 _CFSVLGFCK(gl)SSQVQR_
XRCC5 Ubiquitylation K481 -1.648 0.087 _TDTLEDLFPTTK(gl)IPNPR_
XRCC5 Ubiquitylation K532 0.343 -0.001 _SQIPLSK(gl)IK_
XRCC5 Ubiquitylation K534 -0.146 0.207 _SQIPLSKIK(gl)_
XRCC5 Ubiquitylation K543 0.666 0.157 _TLFPLIEAK(gl)KK_
XRCC5 Ubiquitylation K544 0.165 0.157 _TLFPLIEAKK(gl)_
XRCC5 Ubiquitylation K660 0.644 1.285 _FNNFLK(gl)ALQEK_
XRCC5 Ubiquitylation K665 0.630 0.990 _ALQEK(gl)VEIK_
XRCC5 Ubiquitylation K702 0.626 0.332 _EEASGSSVTAEEAK(gl)K_
XRCC5 Ubiquitylation K703 0.743 0.332 _EEASGSSVTAEEAKK(gl)_
XRCC6 Phosphorylation S27 0.932 0.873 _TEGDEEAEEEQEENLEAS(ph)GDYK_
XRCC6 Ubiquitylation K114 -0.534 -0.728 _NIYVLQELDNPGAK(gl)R_
XRCC6 Ubiquitylation K123 -0.756 _ILELDQFK(gl)GQQGQK_
XRCC6 Ubiquitylation K129 0.079 -0.683 _ILELDQFKGQQGQK(gl)R_
XRCC6 Ubiquitylation K182 -1.603 _IMLFTNEDNPHGNDSAK(gl)ASR_
XRCC6 Ubiquitylation K282 -2.587 _ALK(gl)PPPIK_
XRCC6 Ubiquitylation K287 -1.436 -2.286 _ALKPPPIK(gl)LYR_
XRCC6 Ubiquitylation K299 -0.535 -0.792 _ETNEPVKTK(gl)TR_
XRCC6 Ubiquitylation K317 -0.584 -0.964 _TFNTSTGGLLLPSDTK(gl)R_
XRCC6 Ubiquitylation K331 -1.666 _QIILEK(gl)EETEELKR_
XRCC6 Ubiquitylation K338 -1.479 -1.003 _QIILEKEETEELK(gl)R_
XRCC6 Ubiquitylation K451 -1.713 -1.901 _MPFTEK(gl)IMATPEQVGK_
XRCC6 Phosphorylation T455 -0.085 0.348 _IMAT(ph)PEQVGK_
XRCC6 Ubiquitylation K461 0.239 -0.409 _IMATPEQVGK(gl)MK_
XRCC6 Ubiquitylation K463 -0.609 -0.641 _MK(gl)AIVEK_
XRCC6 Ubiquitylation K468 -1.302 -0.451 _AIVEK(gl)LR_
XRCC6 Phosphorylation S475 1.136 0.167 _S(ph)DSFENPVLQQHFR_
XRCC6 Phosphorylation S477 1.023 0.034 _SDS(ph)FENPVLQQHFR_
XRCC6 Ubiquitylation K516 -1.089 _VEAMNK(gl)R_
XRCC6 Phosphorylation S560 0.318 0.378 _VEYS(ph)EEELKTHISK_
XRCC6 Ubiquitylation K565 0.021 -0.887 _VEYSEEELK(gl)THISK_
XRCC6 Ubiquitylation K575 0.031 -0.121 _GTLGK(gl)FTVPMLK_
XRCC6 Ubiquitylation K591 0.474 0.187 _AYGLK(gl)SGLK_


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