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Query: PAXIP1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PAXIP1 1 3.328 -1.460 2.910 -0.245 0.364 0.299

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for PAXIP1:


Pubmed-PAXIP1 »
Uniprot-PAXIP1 »
Biogrid-PAXIP1 »
ProteomicsDB-PAXIP1 »

Tumorportal-PAXIP1 »
COSMIC-PAXIP1 »
GenomeRNAi-PAXIP1 »
Genecards-PAXIP1


Protein-protein Interactions for PAXIP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCNB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP55 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPX2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC97 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PAXIP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members BRCT_dom IPR001357 1.59


Protein complexes (CORUM database) featuring PAXIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5197 PTIP-DNA damage response complex Database 0.94
Category members Corum 5195 PTIP-HMT complex Database 0.33
Category members Corum 3075 UTX-MLL2/3 complex Database 0


Categories featuring PAXIP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0006310 DNA recombination Database 3.14
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0051568 histone H3-K4 methylation Database 1.7
Category members GO Category GO:0010212 response to ionizing radiation Database 1.66
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0051571 positive regulation of histone H3-K4 methylation Database 0.99
Category members GO Category GO:0035097 histone methyltransferase complex Database 0.26
Category members GO Category GO:0060717 chorion development Database 0.2
Category members GO Category GO:0030330 DNA damage response, signal transduction by p53 class mediator Database 0.04
Category members GO Category GO:0001570 vasculogenesis Database 0
Category members GO Category GO:0031398 positive regulation of protein ubiquitination Database 0
Category members GO Category GO:0035066 positive regulation of histone acetylation Database 0
Category members GO Category GO:0043542 endothelial cell migration Database 0
Category members GO Category GO:0045830 positive regulation of isotype switching Database 0
Category members GO Category GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter Database 0
Category members GO Category GO:0060612 adipose tissue development Database 0


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