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DNA damage response, signal transduction by p53 class mediator
(GO:0030330)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
NBN 2 -0.220 -0.170 0.708 0.569 -0.563 0.354
FOXO3 2 -0.410 -0.120
PAXIP1 1 -1.460 2.910 -0.245 0.364 0.299
MYO6 1 -1.580 2.560 0.037 0.700 0.607
MYO6 1 -1.580 2.560 -0.533
USP10 0 -0.120 -0.210 0.958 0.948 0.289 -0.190 -0.313
NDRG1 0 -1.240 1.600 -0.614 1.252 0.551
NDRG1 0 -1.240 1.600
TP53 0 -1.070 1.050 -2.808 0.076 -0.094 0.436 0.497
E2F7 0 0.000 0.720 -2.763 -0.494
TRIAP1 0 -0.430 0.040
MIF 0 1.480 -0.910 -0.887 -0.872 -1.709 0.653

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
E2F7 Phosphorylation S410 0.286 0.865 _HGS(ph)FNTVQASER_
FOXO3 Phosphorylation S12 -1.324 _(ac)AEAPASPAPLS(ph)PLEVELDPEFEPQSRPR_
FOXO3 Phosphorylation S253 2.510 _AVS(ph)MDNSNKYTK_
FOXO3 Phosphorylation S284 4.138 6.011 _AALQTAPESADDS(ph)PSQLSK_
FOXO3 Phosphorylation S421 1.295 _GS(ph)GLGSPTSSFNSTVFGPSSLNSLR_
FOXO3 Phosphorylation S425 1.471 _GSGLGS(ph)PTSSFNSTVFGPSSLNSLR_
MIF Ubiquitylation K78 0.018 0.329 _SYSK(gl)LLCGLLAER_
MYO6 Phosphorylation S266 0.008 _LHLS(ph)SPDNFR_
MYO6 Phosphorylation S267 -0.106 0.501 _LHLSS(ph)PDNFR_
MYO6 Ubiquitylation K285 0.079 _YFANK(gl)ETDKQILQNR_
MYO6 Ubiquitylation K408 0.078 _GTVIK(gl)VPLKVEQANNAR_
MYO6 Ubiquitylation K634 0.366 _ELFESSTNNNKDTKQK(gl)_
MYO6 Ubiquitylation K993 -0.079 1.133 _QK(gl)EEESQQQAVLEQERR_
MYO6 Ubiquitylation K1053 -1.790 _NDGTRPK(gl)MTPEQMAK_
MYO6 Ubiquitylation K1077 -0.135 0.805 _GPAVLATK(gl)AAAGTK_
MYO6 Ubiquitylation K1089 0.440 1.326 _YDLSK(gl)WK_
MYO6 Ubiquitylation K1120 0.732 0.435 _LK(gl)VYHAWK_
MYO6 Ubiquitylation K1126 0.296 _VYHAWK(gl)SK_
MYO6 Ubiquitylation K1142 -1.182 -0.570 _NTETEQRAPK(gl)SVTDYAQQNPAAQIPAR_
MYO6 Ubiquitylation K1184 -1.200 -0.624 _IPFIRPADQYK(gl)DPQSK_
NBN Phosphorylation T335 -1.121 _T(ph)TTPGPSLSQGVSVDEK_
NBN Phosphorylation S341 3.085 _TTTPGPS(ph)LSQGVSVDEK_
NBN Phosphorylation S343 3.710 3.629 _TTTPGPSLS(ph)QGVSVDEK_
NBN Phosphorylation S397 2.719 1.458 _MLS(ph)QDAPTVK_
NBN Phosphorylation S432 -0.192 -0.395 _IPNYQLS(ph)PTK_
NBN Phosphorylation T434 -0.188 -0.683 _IPNYQLSPT(ph)KLPSINK_
NBN Phosphorylation S615 1.985 4.691 _IS(ph)QENEIGKK_
NDRG1 Phosphorylation S2 0.483 0.404 _(ac)S(ph)REMQDVDLAEVKPLVEK_
NDRG1 Ubiquitylation K14 -1.017 _EMQDVDLAEVK(gl)PLVEK_
NDRG1 Ubiquitylation K285 -2.380 _TTLLK(gl)MADCGGLPQISQPAK_
NDRG1 Ubiquitylation K300 -0.507 -0.742 _MADCGGLPQISQPAK(gl)LAEAFK_
NDRG1 Phosphorylation S326 0.379 _S(ph)RTAS(ph)GSSVTSLDGTR_
NDRG1 Phosphorylation T328 0.330 0.373 _SRT(ph)ASGSSVTSLDGTR_
NDRG1 Phosphorylation S330 0.313 -0.175 _TAS(ph)GSSVTSLDGTR_
NDRG1 Phosphorylation S332 0.247 _TASGS(ph)SVTSLDGTR_
NDRG1 Phosphorylation S333 -0.356 -0.210 _TAS(ph)GSS(ph)VTSLDGTR_
NDRG1 Phosphorylation T335 0.708 -0.841 _TAS(ph)GSSVT(ph)SLDGTR_
NDRG1 Phosphorylation S336 -0.491 -1.009 _TAS(ph)GSSVTS(ph)LDGTR_
NDRG1 Phosphorylation S364 -0.164 -0.457 _S(ph)HTSEGAHLDITPNSGAAGNSAGPK_
NDRG1 Phosphorylation T366 -0.144 -0.451 _SHT(ph)SEGAHLDITPNSGAAGNSAGPK_
NDRG1 Phosphorylation S367 -0.333 _SHTS(ph)EGAHLDITPNSGAAGNSAGPK_
NDRG1 Phosphorylation T375 -1.996 -1.540 _SHTSEGAHLDIT(ph)PNSGAAGNSAGPK_
TP53 Ubiquitylation K120 -0.188 _LGFLHSGTAK(gl)SVTCTYSPALNK_
TP53 Ubiquitylation K164 0.157 -1.260 _AMAIYK(gl)QSQHMTEVVR_
TP53 Phosphorylation S314 -0.695 -1.000 _ALPNNTSS(ph)SPQPK_
TP53 Phosphorylation S315 -0.762 -0.959 _RALPNNTSSS(ph)PQPK_
TP53 Ubiquitylation K320 -0.978 _ALPNNTSSSPQPKK(gl)_
TP53 Ubiquitylation K357 -0.231 -0.823 _ELNEALELKDAQAGK(gl)EPGGSR_
TRIAP1 Ubiquitylation K50 -0.199 _YQQCVQK(gl)AIK_
USP10 Phosphorylation S76 0.220 _TPS(ph)YSISSTLNPQAPEFILGCTASK_
USP10 Phosphorylation T208 -0.556 -0.706 _T(ph)CNSPQNSTDSVSDIVPDSPFPGALGSDTR_
USP10 Phosphorylation S211 -0.454 _TCNS(ph)PQNSTDSVSDIVPDSPFPGALGSDTR_
USP10 Phosphorylation S365 -0.539 -0.580 _YS(ph)PPAISPLVSEK_
USP10 Phosphorylation S370 0.978 0.859 _YSPPAIS(ph)PLVSEK_
USP10 Ubiquitylation K512 0.652 _LLTVNK(gl)SSLSEK_
USP10 Phosphorylation S547 0.647 0.385 _LLS(ph)PSNEK_
USP10 Phosphorylation S576 1.011 0.498 _NHSVNEEEQEEQGEGS(ph)EDEWEQVGPR_
USP10 Ubiquitylation K662 -0.003 _ESVQGYTTK(gl)TK_
USP10 Ubiquitylation K664 1.358 _TK(gl)QEVEISR_
USP10 Ubiquitylation K780 0.763 0.364 _VINQYQVVK(gl)PTAER_


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