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Query: USP10

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
USP10 0 5.283 -0.120 -0.210 0.958 0.948 0.289 -0.190 -0.313

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
USP10 Phosphorylation S370 0.978 0.859 _YSPPAIS(ph)PLVSEK_
USP10 Phosphorylation S576 1.011 0.498 _NHSVNEEEQEEQGEGS(ph)EDEWEQVGPR_
USP10 Phosphorylation S547 0.647 0.385 _LLS(ph)PSNEK_
USP10 Ubiquitylation K780 0.763 0.364 _VINQYQVVK(gl)PTAER_
USP10 Ubiquitylation K662 -0.003 _ESVQGYTTK(gl)TK_
USP10 Phosphorylation S211 -0.454 _TCNS(ph)PQNSTDSVSDIVPDSPFPGALGSDTR_
USP10 Phosphorylation S365 -0.539 -0.580 _YS(ph)PPAISPLVSEK_
USP10 Phosphorylation T208 -0.556 -0.706 _T(ph)CNSPQNSTDSVSDIVPDSPFPGALGSDTR_
USP10 Phosphorylation S76 0.220 _TPS(ph)YSISSTLNPQAPEFILGCTASK_
USP10 Ubiquitylation K512 0.652 _LLTVNK(gl)SSLSEK_
USP10 Ubiquitylation K664 1.358 _TK(gl)QEVEISR_

Background Information for USP10:


Pubmed-USP10 »
Uniprot-USP10 »
Biogrid-USP10 »
ProteomicsDB-USP10 »

Tumorportal-USP10 »
COSMIC-USP10 »
GenomeRNAi-USP10 »
Genecards-USP10


Protein-protein Interactions for USP10
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IBTK Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait NPM1 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015


Protein Domains in USP10
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members UCH/PAN2 IPR028889 0.62
Category members Peptidase_C19_UCH IPR001394 0.53
Category members Ataxin-2_C IPR009818 0.19


Protein complexes (CORUM database) featuring USP10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring USP10
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0004843 ubiquitin-specific protease activity Database 3.28
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0004221 ubiquitin thiolesterase activity Database 1.36
Category members GO Category GO:0016579 protein deubiquitination Database 1.32
Category members GO Category GO:0005769 early endosome Database 1.26
Category members GO Category GO:0004197 cysteine-type endopeptidase activity Database 0.38
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0030330 DNA damage response, signal transduction by p53 class mediator Database 0.04
Category members GO Category GO:0044325 ion channel binding Database 0.03
Category members GO Category GO:0006914 autophagy Database 0
Category members GO Category GO:0010506 regulation of autophagy Database 0


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