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Results for the Category
histone methyltransferase complex
(GO:0035097)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
KMT2D 2 0.250 -0.290 -1.403 -0.404
HDAC9 1 -1.710 3.420
SETD1B 1 2.330 -1.220
SETD1B 1 2.330 -1.220 0.612 0.369 0.153 -0.098 -0.141
PAXIP1 1 -1.460 2.910 -0.245 0.364 0.299
WDR82 1 -1.220 1.640 -0.017 1.342 1.794 0.081 0.046
JARID2 0 -1.180 1.730 -1.360 -1.367
KMT2C 0 0.730 0.280 -1.099 0.032 -0.195
CBX5 0 0.350 -0.490 0.332 -0.485 0.744 0.961 0.512
SETD1A 0 1.000 -0.490 0.612 0.369 0.153 -0.098 -0.141
RBBP5 0 -0.150 -0.170 0.443 0.219 0.902 0.167 0.464
ASH2L 0 -0.380 -0.020 0.463 -0.135 0.610 0.279 0.403
MEN1 0 1.080 -1.150 0.101 0.684 -0.063
MEN1 0 1.080 -1.150 0.395
MEN1 0 1.080 -1.150
KDM6A 0 1.910 -0.840 -0.406 0.870
KDM6A 0 1.910 -0.840 -0.542 -0.153
CXXC1 0 -0.510 0.300 0.959 0.654 -0.921
DPY30 0 -0.340 1.470
PA1 0
WDR5 0 0.230 0.330 -0.088 -0.237 0.506 0.098 -0.100
ZNF335 0 1.750 -1.310
NCOA6 0 -0.430 0.770 -0.167 0.096

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
CBX5 Phosphorylation S14 -0.620 0.260 _RTADSSSS(ph)EDEEEYVVEK_
CBX5 Ubiquitylation K32 1.081 _VVK(gl)GQVEYLLK_
CBX5 Ubiquitylation K68 1.329 _NLDCPELISEFMK(gl)K_
CBX5 Ubiquitylation K69 0.893 _NLDCPELISEFMKK(gl)_
CBX5 Ubiquitylation K91 1.360 _K(gl)SNFSNSADDIK_
CBX5 Phosphorylation S92 0.064 -0.325 _RKS(ph)NFSNSADDIK_
CBX5 Ubiquitylation K102 1.233 1.344 _KSNFSNSADDIK(gl)SK_
CBX5 Ubiquitylation K154 0.568 0.740 _WKDTDEADLVLAK(gl)EANVK_
DPY30 Ubiquitylation K35 0.838 _IVENEK(gl)INAEK_
DPY30 Ubiquitylation K40 -0.950 _IVENEKINAEK(gl)SSK_
DPY30 Ubiquitylation K45 0.119 _QK(gl)VDLQSLPTR_
HDAC9 Phosphorylation S265 -0.390 _RS(ph)SPLLR_
HDAC9 Phosphorylation S266 -0.821 -0.598 _RSS(ph)PLLR_
JARID2 Phosphorylation S455 -0.219 -0.009 _LEEAHQAEKPQS(ph)PPK_
KDM6A Phosphorylation S866 -0.439 _TDNS(ph)VASSPSSAISTATPS(ph)PK_
KDM6A Phosphorylation S870 0.867 -0.013 _TDNSVASS(ph)PSSAISTATPSPK_
KDM6A Phosphorylation S872 0.757 _TDNSVASSPS(ph)SAISTATPSPK_
KDM6A Phosphorylation S876 -0.001 _TDNSVAS(ph)SPSSAIS(ph)TATPSPK_
KDM6A Phosphorylation T879 -0.585 0.018 _TDNSVASS(ph)PSSAISTAT(ph)PSPK_
KDM6A Phosphorylation S881 -0.285 -0.548 _TDNSVASS(ph)PSSAISTATPS(ph)PK_
KMT2C Phosphorylation S2811 0.831 0.317 _TLVLSDKHS(ph)PQK_
KMT2C Phosphorylation S4034 -1.421 -1.557 _EEPPEPVPS(ph)PIIPILPSTAGK_
KMT2D Phosphorylation S373 -0.031 _FS(ph)PPEPGDTPTDEPDALYVACQGQPK_
KMT2D Phosphorylation T1261 0.575 _LCT(ph)DSLPETDDSLLCDAGTAISGGK_
KMT2D Ubiquitylation K1610 -0.606 _NLTM(ox)SPLHK(gl)R_
KMT2D Phosphorylation S1671 -0.219 -0.187 _LEGPVS(ph)PDVEPGKEETEESK_
KMT2D Phosphorylation T1843 -0.551 -0.988 _ADT(ph)PGPEDGGVK_
KMT2D Phosphorylation T1865 0.019 0.146 _ASPVPSDPEKPGT(ph)PGEGM(ox)LSSDLDR_
KMT2D Phosphorylation T2229 -0.146 -0.368 _PGAGQPGEFHTT(ph)PPGTPR_
KMT2D Phosphorylation S2239 0.516 _HQPS(ph)TPDPFLKPR_
KMT2D Phosphorylation T2240 0.562 -0.611 _HQPST(ph)PDPFLKPR_
KMT2D Phosphorylation S2274 -0.226 -0.352 _ASEPLLS(ph)PPPFGESR_
KMT2D Phosphorylation S2640 1.530 1.528 _SGITS(ph)PVEKR_
KMT2D Phosphorylation S3130 -0.430 -0.596 _VEEGGRHPS(ph)PCQFTIATPK_
KMT2D Phosphorylation S4359 0.300 0.037 _VS(ph)PAAAQLADTLFSK_
KMT2D Phosphorylation S4738 -0.391 -0.488 _ALS(ph)PVIPLIPR_
KMT2D Phosphorylation S4822 -0.518 0.106 _IPNSYEVLFPES(ph)PAR_
KMT2D Phosphorylation S4849 -0.135 2.378 _GLEGKS(ph)PDTGPDWLK_
MEN1 Ubiquitylation K8 -1.132 0.088 _AAQK(gl)TLFPLR_
MEN1 Phosphorylation S218 -0.820 _RES(ph)KPEEPPPPK_
PA1 Phosphorylation S237 -0.784 -0.806 _DLFSLDSEDPSPAS(ph)PPLR_
RBBP5 Ubiquitylation K157 -0.051 _DQNK(gl)VLVCPMK_
RBBP5 Ubiquitylation K207 -0.452 _RGEYIYTGNAK(gl)GK_
RBBP5 Ubiquitylation K209 -0.452 _RGEYIYTGNAK(gl)GK_
SETD1A Phosphorylation S468 -0.398 -0.391 _S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1A Phosphorylation S470 -0.480 _S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1A Phosphorylation S915 -0.500 _PS(ph)TPAEEDEDDPEQEK_
SETD1A Phosphorylation T916 -0.121 -0.349 _PST(ph)PAEEDEDDPEQEK_
SETD1A Phosphorylation S1103 -0.612 -0.521 _VAGS(ph)PVTPLPEQEASPAR_
SETD1B Phosphorylation S468 -0.398 -0.391 _S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1B Phosphorylation S470 -0.480 _S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1B Phosphorylation S915 -0.500 _PS(ph)TPAEEDEDDPEQEK_
SETD1B Phosphorylation T916 -0.121 -0.349 _PST(ph)PAEEDEDDPEQEK_
SETD1B Phosphorylation S984 -0.021 0.430 _LRPS(ph)TSVDEEDEESERER_
SETD1B Phosphorylation S1103 -0.612 -0.521 _VAGS(ph)PVTPLPEQEASPAR_
WDR5 Ubiquitylation K27 -1.584 _AQPTPSSSATQSK(gl)PTPVKPNYALK_
WDR5 Ubiquitylation K32 -1.722 _AQPTPSSSATQSKPTPVK(gl)PNYALK_
WDR5 Ubiquitylation K120 0.445 _IWDVSSGK(gl)CLK_
WDR5 Ubiquitylation K245 0.475 _LWDYSK(gl)GK_
WDR5 Ubiquitylation K247 0.475 _LWDYSK(gl)GK_
WDR82 Ubiquitylation K2 0.623 _MK(gl)LTDSVLR_
WDR82 Ubiquitylation K63 -0.009 _K(gl)YGVDLIR_
ZNF335 Phosphorylation S976 -1.197 -1.248 _DGPEPPS(ph)PAK_


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