bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: KMT2D

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KMT2D 2 1.495 0.250 -0.290 -1.403 -0.404

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KMT2D Phosphorylation S4849 -0.135 2.378 _GLEGKS(ph)PDTGPDWLK_
KMT2D Phosphorylation S2640 1.530 1.528 _SGITS(ph)PVEKR_
KMT2D Phosphorylation T1261 0.575 _LCT(ph)DSLPETDDSLLCDAGTAISGGK_
KMT2D Phosphorylation T1865 0.019 0.146 _ASPVPSDPEKPGT(ph)PGEGM(ox)LSSDLDR_
KMT2D Phosphorylation S4822 -0.518 0.106 _IPNSYEVLFPES(ph)PAR_
KMT2D Phosphorylation S4359 0.300 0.037 _VS(ph)PAAAQLADTLFSK_
KMT2D Phosphorylation S1671 -0.219 -0.187 _LEGPVS(ph)PDVEPGKEETEESK_
KMT2D Phosphorylation S2274 -0.226 -0.352 _ASEPLLS(ph)PPPFGESR_
KMT2D Phosphorylation T2229 -0.146 -0.368 _PGAGQPGEFHTT(ph)PPGTPR_
KMT2D Phosphorylation S4738 -0.391 -0.488 _ALS(ph)PVIPLIPR_
KMT2D Phosphorylation S3130 -0.430 -0.596 _VEEGGRHPS(ph)PCQFTIATPK_
KMT2D Phosphorylation T2240 0.562 -0.611 _HQPST(ph)PDPFLKPR_
KMT2D Phosphorylation T1843 -0.551 -0.988 _ADT(ph)PGPEDGGVK_
KMT2D Phosphorylation S373 -0.031 _FS(ph)PPEPGDTPTDEPDALYVACQGQPK_
KMT2D Ubiquitylation K1610 -0.606 _NLTM(ox)SPLHK(gl)R_
KMT2D Phosphorylation S2239 0.516 _HQPS(ph)TPDPFLKPR_

Background Information for KMT2D:


Pubmed-KMT2D »
Uniprot-KMT2D »
Biogrid-KMT2D »
ProteomicsDB-KMT2D »

Tumorportal-KMT2D »
COSMIC-KMT2D »
GenomeRNAi-KMT2D »
Genecards-KMT2D


Protein-protein Interactions for KMT2D
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in KMT2D
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members HMG_box_dom IPR009071 0.31
Category members SET_dom IPR001214 0.29
Category members FYrich_N IPR003888 0.17
Category members FYrich_C IPR003889 0.17
Category members Post-SET_dom IPR003616 0.03
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring KMT2D
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1399 WDR5-ASH2L-RBBP5-MLL2 complex Database 0.47
Category members Corum 1401 MOF complex Database 0.09
Category members Corum 1400 ASCOM complex Database 0
Category members Corum 3075 UTX-MLL2/3 complex Database 0


Categories featuring KMT2D
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0051568 histone H3-K4 methylation Database 1.7
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0018024 histone-lysine N-methyltransferase activity Database 0.73
Category members GO Category GO:0043627 response to estrogen Database 0.4
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0035097 histone methyltransferase complex Database 0.26
Category members GO Category GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway Database 0.25
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members Disease phenotype Kabuki_syndrome Kabuki syndrome Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0048477 oogenesis Database 0.11
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0001555 oocyte growth Database 0
Category members GO Category GO:0006342 chromatin silencing Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0008168 methyltransferase activity Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0


.

© Copyright Svejstrup Laboratory 2015