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response to estrogen
(GO:0043627)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
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Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
HSP90AA1 3 -0.150 0.150 0.395 1.024 -1.280 0.611 0.460
HSP90AA1 3 0.170 -0.420 0.395 1.024 -1.280 0.611 0.460
BRCA1 2 0.200 -0.140 0.433 0.018 0.146
KMT2D 2 0.250 -0.290 -1.403 -0.404
CTNNA1 1 -0.520 1.660 -0.690 -1.164
CTNNA1 1 -0.520 1.660 0.139 0.436 0.323
TBL1Y 1 -1.630 3.050 0.090 -3.400 0.909 0.103 0.241
CCND1 1 -1.820 3.470
TRIM25 1 -0.120 -0.240 0.224 -1.159
GBA 1 -1.380 2.580 0.407 0.357 0.150
HMOX1 0 0.330 0.220 -1.817 -1.289
EP300 0 -1.210 1.320 -1.089 -1.694 -0.723
TBL1X 0 -0.240 -0.140 0.090 -3.400 0.909 0.103 0.241
CAV1 0 1.150 -0.150
CAV1 0 1.150 -0.150
CAV1 0 1.150 -0.150
GLI3 0 -0.980 1.650
GATA3 0 0.000 -0.660
RBBP5 0 -0.150 -0.170 0.443 0.219 0.902 0.167 0.464
APOA1 0 0.850 -0.420 -3.959
TGFB3 0 0.900 -0.540
ASH2L 0 -0.380 -0.020 0.463 -0.135 0.610 0.279 0.403
GSTM3 0 -0.400 0.800
GATA4 0 -0.670 0.350
GATA6 0 -0.210 -0.020 -0.027 -0.582 -0.834
CTNNB1 0 0.490 -0.230
CTNNB1 0 0.490 -0.230 -0.415 0.628 0.215
ZNF366 0 0.270 -0.120 0.668

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
BRCA1 Phosphorylation S123 0.465 0.445 _KENNSPEHLKDEVS(ph)IIQSM(ox)GYR_
BRCA1 Phosphorylation S753 2.662 4.077 _VSNNAEDPKDLMLS(ph)GER_
BRCA1 Phosphorylation S1009 0.733 1.028 _KNLLEENFEEHSM(ox)S(ph)PER_
BRCA1 Phosphorylation S1546 1.821 2.105 _NYPS(ph)QEELIK_
BRCA1 Phosphorylation S1564 3.065 _VVDVEEQQLEES(ph)GPHDLTETSYLPR_
BRCA1 Phosphorylation S1664 1.120 _EKPELTAS(ph)TER_
CAV1 Ubiquitylation K5 0.591 0.963 _(ac)SGGK(gl)YVDSEGHLYTVPIR_
CAV1 Phosphorylation S6 0.836 0.688 _(ac)ADELS(ph)EKQVYDAHTK_
CAV1 Ubiquitylation K8 0.244 0.734 _(ac)ADELSEK(gl)QVYDAHTK_
CAV1 Ubiquitylation K26 0.724 0.894 _EQGNIYK(gl)PNNK_
CAV1 Ubiquitylation K30 -0.008 0.317 _EQGNIYKPNNK(gl)AMADELSEK_
CAV1 Ubiquitylation K39 0.690 1.170 _AMADELSEK(gl)QVYDAHTK_
CAV1 Phosphorylation S76 0.607 0.527 _AMADELS(ph)EK_
CAV1 Ubiquitylation K176 -0.259 _INLQK(gl)EI_
CCND1 Ubiquitylation K33 -0.490 _AMLK(gl)AEETCAPSVSYFK_
CCND1 Ubiquitylation K46 -1.016 -0.036 _AEETCAPSVSYFK(gl)CVQK_
CCND1 Ubiquitylation K95 -0.733 -0.137 _FLSLEPVK(gl)K_
CCND1 Ubiquitylation K96 -0.846 -0.155 _FLSLEPVKK(gl)_
CCND1 Ubiquitylation K238 0.245 _VIK(gl)CDPDCLR_
CTNNA1 Ubiquitylation K16 -0.194 -0.141 _WDPK(gl)SLEIR_
CTNNA1 Ubiquitylation K45 -1.131 -0.728 _LLEPLVTQVTTLVNTNSK(gl)GPSNK_
CTNNA1 Ubiquitylation K120 -0.333 _AAAGEFADDPCSSVK(gl)R_
CTNNA1 Ubiquitylation K414 0.977 _NGNEK(gl)EVKEYAQVFR_
CTNNA1 Ubiquitylation K417 0.211 _NGNEK(gl)EVKEYAQVFR_
CTNNA1 Phosphorylation S641 -0.056 0.089 _TPEELDDS(ph)DFETEDFDVR_
CTNNA1 Phosphorylation T654 0.808 0.392 _SRT(ph)SVQTEDDQLIAGQSAR_
CTNNA1 Phosphorylation S655 1.043 0.882 _SRTS(ph)VQTEDDQLIAGQSAR_
CTNNA1 Ubiquitylation K683 3.760 -0.837 _AIMAQLPQEQKAK(gl)_
CTNNA1 Ubiquitylation K747 -0.384 _NTSDVISAAK(gl)K_
CTNNA1 Ubiquitylation K748 -0.083 -0.384 _NTSDVISAAKK(gl)_
CTNNB1 Ubiquitylation K158 -1.265 _AIPELTK(gl)LLNDEDQVVVNK_
CTNNB1 Ubiquitylation K180 -0.546 -0.636 _AAVM(ox)VHQLSK(gl)K_
CTNNB1 Ubiquitylation K181 -0.717 -0.729 _AAVMVHQLSKK(gl)_
CTNNB1 Phosphorylation S191 -0.024 0.129 _S(ph)PQMVSAIVR_
CTNNB1 Ubiquitylation K435 -0.350 _NK(gl)MM(ox)VCQVGGIEALVR_
CTNNB1 Ubiquitylation K496 -1.262 _LHYGLPVVVK(gl)_
CTNNB1 Phosphorylation S552 1.233 1.224 _RTS(ph)MGGTQQQFVEGVR_
CTNNB1 Phosphorylation T556 1.275 0.995 _RTSM(ox)GGT(ph)QQQFVEGVR_
CTNNB1 Ubiquitylation K671 -0.941 -0.934 _MSEDKPQDYK(gl)K_
EP300 Phosphorylation S1038 -0.672 -0.349 _TEIKEEEDQPSTSATQSS(ph)PAPGQSK_
EP300 Phosphorylation S1726 0.994 0.627 _LGLGLDDESNNQQAAATQS(ph)PGDSRR_
EP300 Phosphorylation S2328 -1.092 0.725 _PQSQPPHSSPS(ph)PR_
GATA3 Phosphorylation S162 -1.195 -0.563 _DVS(ph)PDPSLSTPGSAGSAR_
GATA4 Phosphorylation S109 -0.520 -0.425 _FS(ph)FPGTTGSLAAAAAAAAAR_
GATA4 Phosphorylation S407 -0.185 0.124 _LS(ph)PQGYASPVSQSPQTSSK_
GLI3 Phosphorylation S664 -0.582 -0.252 _S(ph)PGRPTQGALGEQQDLSNTTSK_
GSTM3 Ubiquitylation K79 -0.485 _NK(gl)ITQSNAILR_
HMOX1 Ubiquitylation K243 -0.972 _ASNK(gl)VQDSAPVETPR_
HMOX1 Ubiquitylation K256 -1.769 _GK(gl)PPLNTR_
HSP90AA1 Ubiquitylation K69 0.820 -0.090 _YESLTDPSK(gl)LDSGK_
HSP90AA1 Ubiquitylation K74 0.543 _LDSGK(gl)ELHINLIPNKQDR_
HSP90AA1 Ubiquitylation K112 1.304 1.601 _ADLINNLGTIAK(gl)SGTK_
HSP90AA1 Ubiquitylation K185 0.963 _GTK(gl)VILHLK_
HSP90AA1 Ubiquitylation K208 1.745 _IKEIVK(gl)K_
HSP90AA1 Phosphorylation S231 2.338 0.649 _DKEVS(ph)DDEAEEK_
HSP90AA1 Phosphorylation S263 0.095 0.173 _ESEDKPEIEDVGS(ph)DEEEEKK_
HSP90AA1 Ubiquitylation K281 1.267 _IK(gl)EKYIDQEELNK_
HSP90AA1 Ubiquitylation K283 1.442 1.226 _EK(gl)YIDQEELNK_
HSP90AA1 Ubiquitylation K292 -0.237 0.506 _YIDQEELNK(gl)TKPIWTR_
HSP90AA1 Ubiquitylation K294 0.315 8.646 _TK(gl)PIWTR_
HSP90AA1 Ubiquitylation K362 0.969 0.946 _NNIK(gl)LYVR_
HSP90AA1 Ubiquitylation K407 0.827 1.121 _EMLQQSK(gl)ILK_
HSP90AA1 Ubiquitylation K443 0.820 0.951 _FYEQFSK(gl)NIK_
HSP90AA1 Ubiquitylation K446 0.314 1.126 _NIK(gl)LGIHEDSQNR_
HSP90AA1 Ubiquitylation K478 0.799 1.624 _YYTSASGDEM(ox)VSLK(gl)DYCTR_
HSP90AA1 Ubiquitylation K539 0.353 1.775 _EFEGK(gl)TLVSVTK_
HSP90AA1 Ubiquitylation K559 -0.316 _EGLELPEDEEEKK(gl)K_
HSP90AA1 Ubiquitylation K565 0.903 _K(gl)TKFENLCK_
HSP90AA1 Ubiquitylation K567 0.710 _TK(gl)FENLCK_
HSP90AA1 Ubiquitylation K576 0.874 _IMK(gl)DILEK_
HSP90AA1 Ubiquitylation K581 0.540 0.738 _DILEK(gl)KVEK_
HSP90AA1 Ubiquitylation K582 0.063 0.470 _K(gl)VEKVVVSNR_
HSP90AA1 Ubiquitylation K615 0.715 0.751 _IMK(gl)AQALR_
HSP90AA1 Ubiquitylation K631 0.361 0.974 _DNSTMGYMAAK(gl)K_
KMT2D Phosphorylation S373 -0.031 _FS(ph)PPEPGDTPTDEPDALYVACQGQPK_
KMT2D Phosphorylation T1261 0.575 _LCT(ph)DSLPETDDSLLCDAGTAISGGK_
KMT2D Ubiquitylation K1610 -0.606 _NLTM(ox)SPLHK(gl)R_
KMT2D Phosphorylation S1671 -0.219 -0.187 _LEGPVS(ph)PDVEPGKEETEESK_
KMT2D Phosphorylation T1843 -0.551 -0.988 _ADT(ph)PGPEDGGVK_
KMT2D Phosphorylation T1865 0.019 0.146 _ASPVPSDPEKPGT(ph)PGEGM(ox)LSSDLDR_
KMT2D Phosphorylation T2229 -0.146 -0.368 _PGAGQPGEFHTT(ph)PPGTPR_
KMT2D Phosphorylation S2239 0.516 _HQPS(ph)TPDPFLKPR_
KMT2D Phosphorylation T2240 0.562 -0.611 _HQPST(ph)PDPFLKPR_
KMT2D Phosphorylation S2274 -0.226 -0.352 _ASEPLLS(ph)PPPFGESR_
KMT2D Phosphorylation S2640 1.530 1.528 _SGITS(ph)PVEKR_
KMT2D Phosphorylation S3130 -0.430 -0.596 _VEEGGRHPS(ph)PCQFTIATPK_
KMT2D Phosphorylation S4359 0.300 0.037 _VS(ph)PAAAQLADTLFSK_
KMT2D Phosphorylation S4738 -0.391 -0.488 _ALS(ph)PVIPLIPR_
KMT2D Phosphorylation S4822 -0.518 0.106 _IPNSYEVLFPES(ph)PAR_
KMT2D Phosphorylation S4849 -0.135 2.378 _GLEGKS(ph)PDTGPDWLK_
RBBP5 Ubiquitylation K157 -0.051 _DQNK(gl)VLVCPMK_
RBBP5 Ubiquitylation K207 -0.452 _RGEYIYTGNAK(gl)GK_
RBBP5 Ubiquitylation K209 -0.452 _RGEYIYTGNAK(gl)GK_
TBL1X Ubiquitylation K102 -0.183 _DK(gl)LAQQQAAAAAAAAAAASQQGSAK_
TBL1Y Ubiquitylation K102 -0.183 _DK(gl)LAQQQAAAAAAAAAAASQQGSAK_
TGFB3 Ubiquitylation K50 -0.557 _GQILSK(gl)LR_
TRIM25 Phosphorylation S114 -0.310 -0.309 _ASAPS(ph)PNAQVACDHCLK_
TRIM25 Ubiquitylation K453 1.749 _AK(gl)VLETFLAK_


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