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Query: TBL1Y

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
TBL1Y 1 0.810 -1.630 3.050 0.090 -3.400 0.909 0.103 0.241

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
TBL1Y Ubiquitylation K102 -0.183 _DK(gl)LAQQQAAAAAAAAAAASQQGSAK_

Background Information for TBL1Y:


Pubmed-TBL1Y »
Uniprot-TBL1Y »
Biogrid-TBL1Y »
ProteomicsDB-TBL1Y »

Tumorportal-TBL1Y »
COSMIC-TBL1Y »
GenomeRNAi-TBL1Y »
Genecards-TBL1Y


Protein-protein Interactions for TBL1Y
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait TBL1Y Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in TBL1Y
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52
Category members G-protein_beta_WD-40_rep IPR020472 0.12
Category members LisH_dimerisation IPR006594 0.06
Category members LisH_dimerisation_subgr IPR013720 0


Protein complexes (CORUM database) featuring TBL1Y
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5614 Emerin complex 32 Database 1.48


Categories featuring TBL1Y
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0043627 response to estrogen Database 0.4
Category members GO Category GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process Database 0.23
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0048545 response to steroid hormone Database 0.11
Category members Pathway Pathway_679 KEGG_WNT_SIGNALING_PATHWAY 0 0.09
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0045444 fat cell differentiation Database 0


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