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Query: GATA6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GATA6 0 -1.463 -0.210 -0.020 -0.027 -0.582 -0.834

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for GATA6:


Pubmed-GATA6 »
Uniprot-GATA6 »
Biogrid-GATA6 »
ProteomicsDB-GATA6 »

Tumorportal-GATA6 »
COSMIC-GATA6 »
GenomeRNAi-GATA6 »
Genecards-GATA6


Protein-protein Interactions for GATA6
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in GATA6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_GATA IPR000679 0.29
Category members GATA_N IPR008013 0.04


Protein complexes (CORUM database) featuring GATA6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GATA6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0042493 response to drug Database 0.66
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0043066 negative regulation of apoptotic process Database 0.6
Category members GO Category GO:0001889 liver development Database 0.51
Category members GO Category GO:0043627 response to estrogen Database 0.4
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0019901 protein kinase binding Database 0.37
Category members GO Category GO:0008134 transcription factor binding Database 0.37
Category members GO Category GO:0001103 RNA polymerase II repressing transcription factor binding Database 0.36
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0032911 negative regulation of transforming growth factor beta1 production Database 0.29
Category members GO Category GO:0030855 epithelial cell differentiation Database 0.28
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0060947 cardiac vascular smooth muscle cell differentiation Database 0.26
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0045766 positive regulation of angiogenesis Database 0.19
Category members GO Category GO:0005667 transcription factor complex Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Disease phenotype Congenital_diaphragmatic_hernia Congenital diaphragmatic hernia Database 0.13
Category members GO Category GO:0003148 outflow tract septum morphogenesis Database 0.13
Category members GO Category GO:0003310 pancreatic A cell differentiation Database 0.13
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members Disease phenotype TETRALOGY_OF_FALLOT TETRALOGY OF FALLOT Database 0.11
Category members GO Category GO:0071158 positive regulation of cell cycle arrest Database 0.11
Category members GO Category GO:0051891 positive regulation of cardioblast differentiation Database 0.1
Category members GO Category GO:0060045 positive regulation of cardiac muscle cell proliferation Database 0.09
Category members GO Category GO:0035987 endodermal cell differentiation Database 0.08
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0003309 type B pancreatic cell differentiation Database 0.05
Category members GO Category GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding Database 0.05
Category members GO Category GO:0060430 lung saccule development Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0031016 pancreas development Database 0.01
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_119 PID_HES_HEY_PATHWAY 0 0
Category members Disease phenotype Atrial_septal_defect_ostium_secundum_type Atrial septal defect ostium secundum type Database 0
Category members Disease phenotype Complete_atrioventricular_canal_-_ventricle_hypoplasia Complete atrioventricular canal - ventricle hypoplasia Database 0
Category members Disease phenotype Conotruncal_heart_malformations Conotruncal heart malformations Database 0
Category members Disease phenotype Familial_atrial_fibrillation Familial atrial fibrillation Database 0
Category members GO Category GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity Database 0
Category members GO Category GO:0003705 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006644 phospholipid metabolic process Database 0
Category members GO Category GO:0007493 endodermal cell fate determination Database 0
Category members GO Category GO:0008584 male gonad development Database 0
Category members GO Category GO:0010468 regulation of gene expression Database 0
Category members GO Category GO:0014898 cardiac muscle hypertrophy in response to stress Database 0
Category members GO Category GO:0035239 tube morphogenesis Database 0
Category members GO Category GO:0048645 organ formation Database 0
Category members GO Category GO:0048738 cardiac muscle tissue development Database 0
Category members GO Category GO:0051145 smooth muscle cell differentiation Database 0
Category members GO Category GO:0055007 cardiac muscle cell differentiation Database 0
Category members GO Category GO:0060486 Clara cell differentiation Database 0
Category members GO Category GO:0060510 Type II pneumocyte differentiation Database 0
Category members GO Category GO:0060575 intestinal epithelial cell differentiation Database 0
Category members GO Category GO:0070848 response to growth factor Database 0
Category members GO Category GO:0071371 cellular response to gonadotropin stimulus Database 0
Category members GO Category GO:0071456 cellular response to hypoxia Database 0


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