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Query: ASH2L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ASH2L 0 1.600 -0.380 -0.020 0.463 -0.135 0.610 0.279 0.403

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for ASH2L:


Pubmed-ASH2L »
Uniprot-ASH2L »
Biogrid-ASH2L »
ProteomicsDB-ASH2L »

Tumorportal-ASH2L »
COSMIC-ASH2L »
GenomeRNAi-ASH2L »
Genecards-ASH2L


Protein-protein Interactions for ASH2L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CXXC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SET Cat. description Hein, Mann, Cell 2015
Category members IP bait SETD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC69 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CXXC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EFHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HCFC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ASH2L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members B30.2/SPRY IPR001870 0
Category members SPRY_dom IPR003877 0
Category members ConA-like_lec_gl_sf IPR008985 0


Protein complexes (CORUM database) featuring ASH2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2721 HCF-1 complex Database 2.08
Category members Corum 2730 Set1B complex Database 1.09
Category members Corum 2731 Set1A complex Database 0.62
Category members Corum 1399 WDR5-ASH2L-RBBP5-MLL2 complex Database 0.47
Category members Corum 1254 Menin-associated histone methyltransferase complex Database 0.35
Category members Corum 5195 PTIP-HMT complex Database 0.33
Category members Corum 5386 MLL1-WDR5 complex Database 0.31
Category members Corum 1256 MLL-HCF complex Database 0.3
Category members Corum 1400 ASCOM complex Database 0
Category members Corum 3075 UTX-MLL2/3 complex Database 0


Categories featuring ASH2L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0006974 cellular response to DNA damage stimulus Database 3.57
Category members GO Category GO:0051568 histone H3-K4 methylation Database 1.7
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0042800 histone methyltransferase activity (H3-K4 specific) Database 0.73
Category members GO Category GO:0048188 Set1C/COMPASS complex Database 0.64
Category members GO Category GO:0071339 MLL1 complex Database 0.45
Category members GO Category GO:0043627 response to estrogen Database 0.4
Category members GO Category GO:0035097 histone methyltransferase complex Database 0.26
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0030097 hemopoiesis Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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