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positive regulation of intracellular estrogen receptor signaling pathway
(GO:0033148)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

 Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
DDX17 2 0.430 0.190
DDX17 2 0.430 0.190 -0.510 -0.742 -0.115 0.045 0.000
KMT2D 2 0.250 -0.290 -1.403 -0.404
MED1 1 0.780 -0.520 -1.530 -0.219
DDX5 0 -1.650 2.390
FOXA1 0 1.190 -0.010
SKP2 0 0.030 0.690
SKP2 0 0.030 0.690
PAK1 0 1.190 -0.630

PTM Sites:

 Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
DDX17 Phosphorylation T57 -3.266 _ESAAPAAAPTAEAPPPSVVT(ph)RPEPQALPSPAIR_
DDX17 Phosphorylation S66 -1.474 -2.596 _ESAAPAAAPTAEAPPPSVVTRPEPQALPS(ph)PAIR_
DDX17 Ubiquitylation K197 -0.288 0.192 _LK(gl)STCIYGGAPK_
DDX17 Ubiquitylation K207 -0.829 0.102 _STCIYGGAPK(gl)GPQIR_
DDX17 Ubiquitylation K264 -1.652 _K(gl)IVDQIRPDR_
DDX17 Ubiquitylation K271 -0.079 0.464 _ELAQQVQQVADDYGK(gl)CSR_
DDX17 Ubiquitylation K517 -0.580 0.187 _STNK(gl)GTAYTFFTPGNLK_
DDX17 Ubiquitylation K530 -0.050 0.759 _GTAYTFFTPGNLK(gl)QAR_
DDX17 Phosphorylation S675 1.927 1.128 _S(ph)SQSSSQQFSGIGR_
DDX17 Phosphorylation S680 1.413 3.083 _SSQSSS(ph)QQFSGIGR_
DDX5 Ubiquitylation K197 -0.288 0.192 _LK(gl)STCIYGGAPK_
DDX5 Ubiquitylation K207 -0.829 0.102 _STCIYGGAPK(gl)GPQIR_
DDX5 Ubiquitylation K264 -1.652 _K(gl)IVDQIRPDR_
FOXA1 Phosphorylation S331 -0.760 -0.866 _TGQLEGAPAPGPAAS(ph)PQTLDHSGATATGGASELK_
KMT2D Phosphorylation S373 -0.031 _FS(ph)PPEPGDTPTDEPDALYVACQGQPK_
KMT2D Phosphorylation T1261 0.575 _LCT(ph)DSLPETDDSLLCDAGTAISGGK_
KMT2D Ubiquitylation K1610 -0.606 _NLTM(ox)SPLHK(gl)R_
KMT2D Phosphorylation S1671 -0.219 -0.187 _LEGPVS(ph)PDVEPGKEETEESK_
KMT2D Phosphorylation T1843 -0.551 -0.988 _ADT(ph)PGPEDGGVK_
KMT2D Phosphorylation T1865 0.019 0.146 _ASPVPSDPEKPGT(ph)PGEGM(ox)LSSDLDR_
KMT2D Phosphorylation T2229 -0.146 -0.368 _PGAGQPGEFHTT(ph)PPGTPR_
KMT2D Phosphorylation S2239 0.516 _HQPS(ph)TPDPFLKPR_
KMT2D Phosphorylation T2240 0.562 -0.611 _HQPST(ph)PDPFLKPR_
KMT2D Phosphorylation S2274 -0.226 -0.352 _ASEPLLS(ph)PPPFGESR_
KMT2D Phosphorylation S2640 1.530 1.528 _SGITS(ph)PVEKR_
KMT2D Phosphorylation S3130 -0.430 -0.596 _VEEGGRHPS(ph)PCQFTIATPK_
KMT2D Phosphorylation S4359 0.300 0.037 _VS(ph)PAAAQLADTLFSK_
KMT2D Phosphorylation S4738 -0.391 -0.488 _ALS(ph)PVIPLIPR_
KMT2D Phosphorylation S4822 -0.518 0.106 _IPNSYEVLFPES(ph)PAR_
KMT2D Phosphorylation S4849 -0.135 2.378 _GLEGKS(ph)PDTGPDWLK_
MED1 Phosphorylation S664 3.368 _DNPAQDFSTLYGSS(ph)PLER_
MED1 Phosphorylation S771 -1.422 _LSS(ph)SDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLR_
MED1 Phosphorylation T1051 -1.201 -1.247 _SQT(ph)PPGVATPPIPK_
MED1 Phosphorylation T1057 -1.294 _SQT(ph)PPGVAT(ph)PPIPK_
MED1 Phosphorylation S1155 0.689 _NSSQSGGKPGS(ph)SPITK_
MED1 Phosphorylation S1156 0.829 1.055 _NSSQSGGKPGSS(ph)PITK_
MED1 Phosphorylation S1192 -0.792 _PSSLM(ox)NPSLSKPNIS(ph)PSHSRPPGGSDK_
MED1 Phosphorylation S1223 1.061 1.013 _AKS(ph)PISSGSGGSHM(ox)SGTSSSSGM(ox)K_
MED1 Phosphorylation S1433 -0.191 _NYGS(ph)PLISGSTPK_
PAK1 Phosphorylation S174 -1.439 -0.597 _AVSETPAVPPVS(ph)EDEDDDDDDATPPPVIAPRPEHTK_
PAK1 Phosphorylation T212 0.312 _SVIEPLPVT(ph)PTR_
PAK1 Phosphorylation T219 -0.560 -0.962 _DVAT(ph)SPISPTENNTT(ph)PPDALTR_
PAK1 Phosphorylation S220 -0.916 -0.774 _DVATS(ph)PISPTENNTTPPDALTR_
PAK1 Phosphorylation S223 1.033 0.153 _DVATSPIS(ph)PTENNTTPPDALTR_
PAK1 Phosphorylation T225 -1.278 _DVATSPISPT(ph)ENNTTPPDALTR_
PAK1 Phosphorylation T230 -1.418 -1.502 _DVATSPISPTENNTT(ph)PPDALTR_
SKP2 Phosphorylation S8 -1.062 _SNLGHPES(ph)PPRK_
SKP2 Phosphorylation S64 -1.144 -1.189 _EEPDSENIPQELLSNLGHPES(ph)PPR_
SKP2 Phosphorylation S75 0.512 0.657 _SKGS(ph)DKDFVIVR_
SKP2 Ubiquitylation K228 -0.475 _LSDPIVNTLAK(gl)NSNLVR_
SKP2 Ubiquitylation K420 -1.178 _LTLQK(gl)PSCL_


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