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Results for the Category
chromatin silencing
(GO:0006342)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
KMT2D 2 0.250 -0.290 -1.403 -0.404
UBR2 0 -0.250 0.600 -1.757
SIRT2 0 0.960 -0.980
SIRT2 0 0.960 -0.980
SIRT1 0 0.910 -0.910
HDAC5 0 -0.830 1.270
HELLS 0 -1.320 1.650 -1.393 -0.483 -0.069 -0.340 -0.345

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
HDAC5 Phosphorylation S265 -0.390 _RS(ph)SPLLR_
HDAC5 Phosphorylation S266 -0.821 -0.598 _RSS(ph)PLLR_
HELLS Ubiquitylation K74 0.655 _LQHLLEK(gl)SNIYSK_
HELLS Phosphorylation S115 0.257 _NS(ph)IDASEEKPVMR_
HELLS Ubiquitylation K474 -0.723 _EVVVYAPLSK(gl)K_
HELLS Ubiquitylation K475 -0.723 _EVVVYAPLSK(gl)K_
HELLS Ubiquitylation K753 0.741 _NHFK(gl)GGQSGLNLSK_
HELLS Ubiquitylation K776 0.359 _ELMELLK(gl)SR_
KMT2D Phosphorylation S373 -0.031 _FS(ph)PPEPGDTPTDEPDALYVACQGQPK_
KMT2D Phosphorylation T1261 0.575 _LCT(ph)DSLPETDDSLLCDAGTAISGGK_
KMT2D Ubiquitylation K1610 -0.606 _NLTM(ox)SPLHK(gl)R_
KMT2D Phosphorylation S1671 -0.219 -0.187 _LEGPVS(ph)PDVEPGKEETEESK_
KMT2D Phosphorylation T1843 -0.551 -0.988 _ADT(ph)PGPEDGGVK_
KMT2D Phosphorylation T1865 0.019 0.146 _ASPVPSDPEKPGT(ph)PGEGM(ox)LSSDLDR_
KMT2D Phosphorylation T2229 -0.146 -0.368 _PGAGQPGEFHTT(ph)PPGTPR_
KMT2D Phosphorylation S2239 0.516 _HQPS(ph)TPDPFLKPR_
KMT2D Phosphorylation T2240 0.562 -0.611 _HQPST(ph)PDPFLKPR_
KMT2D Phosphorylation S2274 -0.226 -0.352 _ASEPLLS(ph)PPPFGESR_
KMT2D Phosphorylation S2640 1.530 1.528 _SGITS(ph)PVEKR_
KMT2D Phosphorylation S3130 -0.430 -0.596 _VEEGGRHPS(ph)PCQFTIATPK_
KMT2D Phosphorylation S4359 0.300 0.037 _VS(ph)PAAAQLADTLFSK_
KMT2D Phosphorylation S4738 -0.391 -0.488 _ALS(ph)PVIPLIPR_
KMT2D Phosphorylation S4822 -0.518 0.106 _IPNSYEVLFPES(ph)PAR_
KMT2D Phosphorylation S4849 -0.135 2.378 _GLEGKS(ph)PDTGPDWLK_
SIRT1 Phosphorylation S14 -0.369 -0.246 _(ac)ADEAALALQPGGS(ph)PSAAGADR_
SIRT1 Phosphorylation S16 -0.306 -1.665 _(ac)ADEAALALQPGGS(ph)PS(ph)AAGADREAASSPAGEPLR_
SIRT1 Phosphorylation S26 -1.047 -0.245 _EAAS(ph)SPAGEPLR_
SIRT1 Phosphorylation S27 0.351 -0.363 _EAASS(ph)PAGEPLR_
SIRT1 Phosphorylation S47 -0.574 -0.607 _S(ph)PGEPGGAAPER_
SIRT1 Ubiquitylation K238 -1.641 _RK(gl)DINTIEDAVK_
SIRT1 Ubiquitylation K499 -2.138 -0.204 _LGGEYAK(gl)LCCNPVK_
SIRT1 Ubiquitylation K578 -2.782 _GCMEEK(gl)PQEVQTSR_
SIRT1 Ubiquitylation K601 -3.051 _NVESIAEQMENPDLK(gl)NVGSSTGEK_
SIRT2 Ubiquitylation K39 0.138 0.076 _NLFSQTLSLGSQK(gl)ER_
SIRT2 Ubiquitylation K140 0.154 1.067 _LLK(gl)DKGLLLR_
SIRT2 Ubiquitylation K142 0.842 1.458 _LLKDK(gl)GLLLR_
SIRT2 Ubiquitylation K270 -0.520 _LLINK(gl)EK_
SIRT2 Phosphorylation S364 -0.719 _EHASIDAQSGAGVPNPS(ph)TSASPK_
SIRT2 Phosphorylation S366 -0.826 _EHASIDAQSGAGVPNPSTS(ph)ASPK_
SIRT2 Phosphorylation S368 -0.366 -0.702 _EHASIDAQSGAGVPNPSTSAS(ph)PK_
UBR2 Ubiquitylation K779 -0.314 -0.531 _FSPGVGQVNATDEIK(gl)R_
UBR2 Phosphorylation S1006 0.165 0.550 _ESS(ph)PTSPVAETEGTIMEESSR_
UBR2 Phosphorylation S1009 0.446 _ESSPTS(ph)PVAETEGTIMEESSR_
UBR2 Ubiquitylation K1138 -1.146 _STVLSK(gl)NR_
UBR2 Ubiquitylation K1187 0.360 0.824 _YFDSVQAK(gl)EQRR_


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