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Query: UBR2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
UBR2 0 0.742 -0.250 0.600 -1.757

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
UBR2 Ubiquitylation K1187 0.360 0.824 _YFDSVQAK(gl)EQRR_
UBR2 Phosphorylation S1006 0.165 0.550 _ESS(ph)PTSPVAETEGTIMEESSR_
UBR2 Phosphorylation S1009 0.446 _ESSPTS(ph)PVAETEGTIMEESSR_
UBR2 Ubiquitylation K779 -0.314 -0.531 _FSPGVGQVNATDEIK(gl)R_
UBR2 Ubiquitylation K1138 -1.146 _STVLSK(gl)NR_

Background Information for UBR2:


Pubmed-UBR2 »
Uniprot-UBR2 »
Biogrid-UBR2 »
ProteomicsDB-UBR2 »

Tumorportal-UBR2 »
COSMIC-UBR2 »
GenomeRNAi-UBR2 »
Genecards-UBR2


Protein-protein Interactions for UBR2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC26 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLRB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MRPL50 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA11 Cat. description Hein, Mann, Cell 2015
Category members IP bait NES Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait SGOL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait TTLL7 Cat. description Hein, Mann, Cell 2015
Category members IP bait ASB6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C2orf3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC130 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRHBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CROCC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEPACAM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HS3ST2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HYAL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INSL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait METTL2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUDT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXPH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PAK7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PNLIPRP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PON2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RGS8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SIL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SMOC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SOD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPINK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UBR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in UBR2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_N-recognin IPR003126 0
Category members ClpS_core IPR003769 0
Category members Znf_N-recognin_met IPR013993 0
Category members Ribosomal_L7/12_C/ClpS-like IPR014719 0


Protein complexes (CORUM database) featuring UBR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring UBR2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0000785 chromatin Database 2.59
Category members Pathway Pathway_764 REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION 0 2.56
Category members Pathway Pathway_832 REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION 0 1.58
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030163 protein catabolic process Database 0.38
Category members GO Category GO:0070728 leucine binding Database 0.36
Category members GO Category GO:0032007 negative regulation of TOR signaling Database 0.33
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0006342 chromatin silencing Database 0
Category members GO Category GO:0007141 male meiosis I Database 0
Category members GO Category GO:0007283 spermatogenesis Database 0
Category members GO Category GO:0033522 histone H2A ubiquitination Database 0
Category members GO Category GO:0071233 cellular response to leucine Database 0


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