RNAi screen result	RNAPII IP (MG132)	CSB IP	CSB IP (MG132)	Chrom.	Chrom. (MG132)	Ubi /Phospo	Ubi /Phospho (MG132)
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Gene name	MGoogle Score	RNAi high	RNAi low	RNAPII-IP (MG132)	CSB-IP	CSB-IP (MG132)	Chrom.	Chrom. (MG132)
SETD2	3	-1.690	2.960	1.619		1.725	-0.978	0.379
WHSC1	2	1.030	-0.990
KMT2D	2	0.250	-0.290				-1.403	-0.404
DOT1L	1	-0.340	0.210				-0.710	-0.145
SETD1B	1	2.330	-1.220
SETD1B	1	2.330	-1.220	0.612	0.369	0.153	-0.098	-0.141
SETD8	1	-0.030	0.060
SETD8	1	0.220	0.320
PRDM6	0
SETD1A	0	1.000	-0.490	0.612	0.369	0.153	-0.098	-0.141
EZH2	0	1.100	-0.960	0.524			0.464	-0.045
ASH1L	0	1.230	-0.360				-0.777	-0.350
PRDM2	0	0.440	-0.560
MEN1	0	1.080	-1.150	0.101			0.684	-0.063
MEN1	0	1.080	-1.150			0.395
MEN1	0	1.080	-1.150
SETDB1	0	0.110	0.270
SETD7	0	-0.330	0.300
WHSC1L1	0	0.780	-0.870				-0.030	0.376
SUV39H2	0	-0.980	2.320				1.259	0.440
NSD1	0	-0.750	1.060				-0.118	-0.211
EHMT1	0	0.540	-0.340	-0.405			0.294	0.151
SMYD3	0	0.150	0.580

Gene name	PTM type	PTM site	UV	UV (MG132)	Sequence
ASH1L	Phosphorylation	S1748	-0.660	-0.694	_SIDAVIATASAPPSSS(ph)PGR_
DOT1L	Phosphorylation	S374	-0.107	-0.003	_VAGPADAPMDS(ph)GAEEEK_
DOT1L	Phosphorylation	S448	0.637	0.950	_KNQTALDALHAQTVSQTAASS(ph)PQDAYR_
DOT1L	Phosphorylation	T772	0.095		_LSGLAAPDYT(ph)RLSPAK_
DOT1L	Phosphorylation	S775	0.015	-0.688	_LSGLAAPDYTRLS(ph)PAK_
DOT1L	Phosphorylation	S834	-1.490	-1.900	_PLS(ph)PGALQLAGEK_
DOT1L	Phosphorylation	S1035	-0.512	-0.045	_GDLPSDSGFS(ph)DPESEAK_
DOT1L	Phosphorylation	S1104	0.384	-0.103	_RASAGTPSLSAGVS(ph)PK_
DOT1L	Phosphorylation	S1213	0.118	-0.125	_IATISLESKS(ph)PPK_
DOT1L	Phosphorylation	S1246	1.598	1.113	_STFS(ph)PISDIGLAK_
EHMT1	Ubiquitylation	K827	-0.048	0.076	_YLIK(gl)AGALVDPK_
EHMT1	Ubiquitylation	K970	0.967	0.775	_DSDVTLKNK(gl)_
EZH2	Ubiquitylation	K61	0.548		_TEILNQEWK(gl)QR_
EZH2	Phosphorylation	S363	0.010	-0.733	_GRLPNNSS(ph)RPSTPTINVLESK_
EZH2	Phosphorylation	S366	-0.266	-0.699	_GRLPNNSSRPS(ph)TPTINVLESK_
EZH2	Phosphorylation	T367	0.320	-0.372	_LPNNSSRPST(ph)PTINVLESK_
EZH2	Phosphorylation	T369		-0.911	_GRLPNNSSRPSTPT(ph)INVLESK_
EZH2	Phosphorylation	T487	-0.501	-0.532	_VKESSIIAPAPAEDVDT(ph)PPR_
EZH2	Ubiquitylation	K569		-0.974	_AQCNTK(gl)QCPCYLAVR_
EZH2	Ubiquitylation	K713		-0.461	_IGIFAK(gl)R_
EZH2	Ubiquitylation	K735	0.038		_YSQADALK(gl)YVGIER_
KMT2D	Phosphorylation	S373	-0.031		_FS(ph)PPEPGDTPTDEPDALYVACQGQPK_
KMT2D	Phosphorylation	T1261		0.575	_LCT(ph)DSLPETDDSLLCDAGTAISGGK_
KMT2D	Ubiquitylation	K1610	-0.606		_NLTM(ox)SPLHK(gl)R_
KMT2D	Phosphorylation	S1671	-0.219	-0.187	_LEGPVS(ph)PDVEPGKEETEESK_
KMT2D	Phosphorylation	T1843	-0.551	-0.988	_ADT(ph)PGPEDGGVK_
KMT2D	Phosphorylation	T1865	0.019	0.146	_ASPVPSDPEKPGT(ph)PGEGM(ox)LSSDLDR_
KMT2D	Phosphorylation	T2229	-0.146	-0.368	_PGAGQPGEFHTT(ph)PPGTPR_
KMT2D	Phosphorylation	S2239	0.516		_HQPS(ph)TPDPFLKPR_
KMT2D	Phosphorylation	T2240	0.562	-0.611	_HQPST(ph)PDPFLKPR_
KMT2D	Phosphorylation	S2274	-0.226	-0.352	_ASEPLLS(ph)PPPFGESR_
KMT2D	Phosphorylation	S2640	1.530	1.528	_SGITS(ph)PVEKR_
KMT2D	Phosphorylation	S3130	-0.430	-0.596	_VEEGGRHPS(ph)PCQFTIATPK_
KMT2D	Phosphorylation	S4359	0.300	0.037	_VS(ph)PAAAQLADTLFSK_
KMT2D	Phosphorylation	S4738	-0.391	-0.488	_ALS(ph)PVIPLIPR_
KMT2D	Phosphorylation	S4822	-0.518	0.106	_IPNSYEVLFPES(ph)PAR_
KMT2D	Phosphorylation	S4849	-0.135	2.378	_GLEGKS(ph)PDTGPDWLK_
MEN1	Ubiquitylation	K8	-1.132	0.088	_AAQK(gl)TLFPLR_
MEN1	Phosphorylation	S218		-0.820	_RES(ph)KPEEPPPPK_
NSD1	Phosphorylation	S1510		0.148	_TATS(ph)PKETVEEGVEHDPGMPASK_
NSD1	Phosphorylation	S2471	-0.515	-0.677	_AAS(ph)PHQVTPQADEK_
PRDM2	Phosphorylation	S643	-0.387	-0.415	_TAS(ph)PPALPK_
PRDM2	Phosphorylation	S739	-2.045	-0.921	_TSS(ph)PPSSPQHSPALR_
PRDM2	Phosphorylation	S796	-0.200	-0.181	_ETVS(ph)PPCFDEYK_
PRDM2	Phosphorylation	S1484		-0.692	_KPLS(ph)PPK_
PRDM6	Phosphorylation	S68	0.643	0.662	_AEPPPDS(ph)LRPR_
SETD1A	Phosphorylation	S468	-0.398	-0.391	_S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1A	Phosphorylation	S470		-0.480	_S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1A	Phosphorylation	S915		-0.500	_PS(ph)TPAEEDEDDPEQEK_
SETD1A	Phosphorylation	T916	-0.121	-0.349	_PST(ph)PAEEDEDDPEQEK_
SETD1A	Phosphorylation	S1103	-0.612	-0.521	_VAGS(ph)PVTPLPEQEASPAR_
SETD1B	Phosphorylation	S468	-0.398	-0.391	_S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1B	Phosphorylation	S470		-0.480	_S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1B	Phosphorylation	S915		-0.500	_PS(ph)TPAEEDEDDPEQEK_
SETD1B	Phosphorylation	T916	-0.121	-0.349	_PST(ph)PAEEDEDDPEQEK_
SETD1B	Phosphorylation	S984	-0.021	0.430	_LRPS(ph)TSVDEEDEESERER_
SETD1B	Phosphorylation	S1103	-0.612	-0.521	_VAGS(ph)PVTPLPEQEASPAR_
SETD2	Phosphorylation	S130	-0.443		_M(ox)EIGDTLSTAEES(ph)SPPK_
SETD2	Phosphorylation	S131	-0.001	-0.163	_M(ox)EIGDTLSTAEESS(ph)PPK_
SETD2	Phosphorylation	S624	0.374	0.432	_LNDS(ph)PTLKK_
SETD2	Phosphorylation	S708	0.398		_TDAVLM(ox)TSDDSVTGSELS(ph)PLVK_
SETD2	Phosphorylation	S742	-1.167	-1.779	_S(ph)ESPFRETEPLVSPHQDK_
SETD2	Phosphorylation	S744	-0.557		_SES(ph)PFRETEPLVSPHQDK_
SETD2	Phosphorylation	T1083		0.552	_NSTLPMEET(ph)SPCSSR_
SETD2	Phosphorylation	S1084		-0.102	_NSTLPMEETS(ph)PCSSR_
SETD2	Phosphorylation	T1872	-0.148	-1.034	_LSTEADTDT(ph)PKK_
SETD2	Phosphorylation	S1885		0.110	_IIS(ph)ENSMDSAISDATSELEGK_
SETD2	Phosphorylation	S1888	1.247	0.067	_IISENS(ph)M(ox)DSAISDATSELEGK_
SETD7	Phosphorylation	S3		-0.012	_(ac)MDS(ph)DDEMVEEAVEGHLDDDGLPHGFCTVTYSSTDR_
SETD8	Ubiquitylation	K234		2.165	_K(gl)SKAELQSEER_
SETD8	Ubiquitylation	K236	-1.450	2.341	_SK(gl)AELQSEER_
SETD8	Ubiquitylation	K267		2.000	_IDLIDGK(gl)GR_
SETD8	Ubiquitylation	K275		2.687	_GVIATK(gl)QFSR_
SETD8	Ubiquitylation	K342		1.991	_LINHSK(gl)CGNCQTK_
SETDB1	Ubiquitylation	K597		-3.267	_GK(gl)NPLLVPLLYDFR_
SETDB1	Phosphorylation	S1066	-0.816	-0.946	_NYGYNPS(ph)PVKPEGLR_
SMYD3	Ubiquitylation	K42		0.263	_SDPLAYTVCK(gl)GSR_
SUV39H2	Ubiquitylation	K129		0.974	_TLKPAIAEYIVK(gl)K_
SUV39H2	Ubiquitylation	K130	0.678	0.667	_TLKPAIAEYIVKK(gl)_
SUV39H2	Phosphorylation	S388	-0.691	-0.068	_GSGDISSDSIDHS(ph)PAKK_
WHSC1	Phosphorylation	T49	-1.049		_GIGT(ph)PPNT(ph)TPIK_
WHSC1	Phosphorylation	T54	-1.049		_GIGT(ph)PPNTT(ph)PIK_
WHSC1	Phosphorylation	T483	-0.839		_RIQDPTEDAEAEDT(ph)PRK_
WHSC1L1	Phosphorylation	S561		1.206	_NEKPTQSVSS(ph)PEATSGSTGSVEK_