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Query: SETD1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SETD1B 1 1.304 2.330 -1.220
SETD1B 1 1.304 2.330 -1.220 0.612 0.369 0.153 -0.098 -0.141

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SETD1B Phosphorylation S984 -0.021 0.430 _LRPS(ph)TSVDEEDEESERER_
SETD1B Phosphorylation T916 -0.121 -0.349 _PST(ph)PAEEDEDDPEQEK_
SETD1B Phosphorylation S468 -0.398 -0.391 _S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1B Phosphorylation S470 -0.480 _S(ph)GSPAPETTNESVPFAQHSSLDSR_
SETD1B Phosphorylation S915 -0.500 _PS(ph)TPAEEDEDDPEQEK_
SETD1B Phosphorylation S1103 -0.612 -0.521 _VAGS(ph)PVTPLPEQEASPAR_

Background Information for SETD1B:


Pubmed-SETD1B »
Uniprot-SETD1B »
Biogrid-SETD1B »
ProteomicsDB-SETD1B »

Tumorportal-SETD1B »
COSMIC-SETD1B »
GenomeRNAi-SETD1B »
Genecards-SETD1B


Protein-protein Interactions for SETD1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CXXC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF18B Cat. description Hein, Mann, Cell 2015
Category members IP bait SETD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait SYNCRIP Cat. description Hein, Mann, Cell 2015
Category members IP bait CXXC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in SETD1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members RRM_dom IPR000504 4.34
Category members SET_dom IPR001214 0.29
Category members Post-SET_dom IPR003616 0.03
Category members COMPASS_Set1_N-SET IPR024657 0


Protein complexes (CORUM database) featuring SETD1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2730 Set1B complex Database 1.09


Categories featuring SETD1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0051568 histone H3-K4 methylation Database 1.7
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0042800 histone methyltransferase activity (H3-K4 specific) Database 0.73
Category members GO Category GO:0018024 histone-lysine N-methyltransferase activity Database 0.73
Category members GO Category GO:0048188 Set1C/COMPASS complex Database 0.64
Category members GO Category GO:0035097 histone methyltransferase complex Database 0.26
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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