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Query: WHSC1L1

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
WHSC1L1 0 1.552 0.780 -0.870 -0.030 0.376

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
WHSC1L1 Phosphorylation S561 1.206 _NEKPTQSVSS(ph)PEATSGSTGSVEK_

Background Information for WHSC1L1:


Pubmed-WHSC1L1 »
Uniprot-WHSC1L1 »
Biogrid-WHSC1L1 »
ProteomicsDB-WHSC1L1 »

Tumorportal-WHSC1L1 »
COSMIC-WHSC1L1 »
GenomeRNAi-WHSC1L1 »
Genecards-WHSC1L1


Protein-protein Interactions for WHSC1L1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BRD2;DKFZp313H139 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KDM1B Cat. description Hein, Mann, Cell 2015
Category members IP bait WHSC1L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait YEATS4 Cat. description Hein, Mann, Cell 2015


Protein Domains in WHSC1L1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members PWWP_dom IPR000313 0.63
Category members SET_dom IPR001214 0.29
Category members Post-SET_dom IPR003616 0.03
Category members AWS_dom IPR006560 0


Protein complexes (CORUM database) featuring WHSC1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring WHSC1L1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0005694 chromosome Database 3.87
Category members GO Category GO:0034968 histone lysine methylation Database 1.1
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0018024 histone-lysine N-methyltransferase activity Database 0.73
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0016571 histone methylation Database 0.08
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0016049 cell growth Database 0


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