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Results for the Category
histone methylation
(GO:0016571)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
DOT1L 1 -0.340 0.210 -0.710 -0.145
CTCFL 1 0.700 -1.150 1.656 0.503 0.229 0.942 0.519
KMT2C 0 0.730 0.280 -1.099 0.032 -0.195
EED 0 -1.210 1.980 0.099 0.896 0.548
EZH2 0 1.100 -0.960 0.524 0.464 -0.045
PRMT8 0 -0.720 1.160 -0.002 -0.505 0.005
PRMT1 0 -0.220 0.380 -1.264 0.067
PRMT1 0 -0.220 0.380 -0.002 -0.505 0.005
MEN1 0 1.080 -1.150 0.101 0.684 -0.063
MEN1 0 1.080 -1.150 0.395
MEN1 0 1.080 -1.150
CARM1 0 -0.160 0.540 -0.032
WHSC1L1 0 0.780 -0.870 -0.030 0.376
NSD1 0 -0.750 1.060 -0.118 -0.211
SUZ12 0 -0.710 0.770 0.451 1.156
SUZ12 0 -0.710 0.770 -0.670 0.955 0.457
EHMT1 0 0.540 -0.340 -0.405 0.294 0.151
SATB1 0 1.140 -1.300 -0.866 0.000
PRMT6 0 -0.440 0.850

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
DOT1L Phosphorylation S374 -0.107 -0.003 _VAGPADAPMDS(ph)GAEEEK_
DOT1L Phosphorylation S448 0.637 0.950 _KNQTALDALHAQTVSQTAASS(ph)PQDAYR_
DOT1L Phosphorylation T772 0.095 _LSGLAAPDYT(ph)RLSPAK_
DOT1L Phosphorylation S775 0.015 -0.688 _LSGLAAPDYTRLS(ph)PAK_
DOT1L Phosphorylation S834 -1.490 -1.900 _PLS(ph)PGALQLAGEK_
DOT1L Phosphorylation S1035 -0.512 -0.045 _GDLPSDSGFS(ph)DPESEAK_
DOT1L Phosphorylation S1104 0.384 -0.103 _RASAGTPSLSAGVS(ph)PK_
DOT1L Phosphorylation S1213 0.118 -0.125 _IATISLESKS(ph)PPK_
DOT1L Phosphorylation S1246 1.598 1.113 _STFS(ph)PISDIGLAK_
EHMT1 Ubiquitylation K827 -0.048 0.076 _YLIK(gl)AGALVDPK_
EHMT1 Ubiquitylation K970 0.967 0.775 _DSDVTLKNK(gl)_
EZH2 Ubiquitylation K61 0.548 _TEILNQEWK(gl)QR_
EZH2 Phosphorylation S363 0.010 -0.733 _GRLPNNSS(ph)RPSTPTINVLESK_
EZH2 Phosphorylation S366 -0.266 -0.699 _GRLPNNSSRPS(ph)TPTINVLESK_
EZH2 Phosphorylation T367 0.320 -0.372 _LPNNSSRPST(ph)PTINVLESK_
EZH2 Phosphorylation T369 -0.911 _GRLPNNSSRPSTPT(ph)INVLESK_
EZH2 Phosphorylation T487 -0.501 -0.532 _VKESSIIAPAPAEDVDT(ph)PPR_
EZH2 Ubiquitylation K569 -0.974 _AQCNTK(gl)QCPCYLAVR_
EZH2 Ubiquitylation K713 -0.461 _IGIFAK(gl)R_
EZH2 Ubiquitylation K735 0.038 _YSQADALK(gl)YVGIER_
KMT2C Phosphorylation S2811 0.831 0.317 _TLVLSDKHS(ph)PQK_
KMT2C Phosphorylation S4034 -1.421 -1.557 _EEPPEPVPS(ph)PIIPILPSTAGK_
MEN1 Ubiquitylation K8 -1.132 0.088 _AAQK(gl)TLFPLR_
MEN1 Phosphorylation S218 -0.820 _RES(ph)KPEEPPPPK_
NSD1 Phosphorylation S1510 0.148 _TATS(ph)PKETVEEGVEHDPGMPASK_
NSD1 Phosphorylation S2471 -0.515 -0.677 _AAS(ph)PHQVTPQADEK_
PRMT1 Ubiquitylation K134 0.077 0.022 _ANK(gl)LDHVVTIIK_
PRMT1 Ubiquitylation K233 -0.894 _DVAIK(gl)EPLVDVVDPK_
PRMT6 Phosphorylation T21 0.891 0.194 _LESGGGGEGGEGT(ph)EEEDGAER_
PRMT8 Ubiquitylation K134 0.077 0.022 _ANK(gl)LDHVVTIIK_
PRMT8 Ubiquitylation K233 -0.894 _DVAIK(gl)EPLVDVVDPK_
SUZ12 Ubiquitylation K341 -0.110 -0.960 _ATWETILDGK(gl)R_
SUZ12 Ubiquitylation K390 -0.696 _NSESLHQENK(gl)PGSVKPTQTIAVK_
SUZ12 Phosphorylation S546 0.533 0.248 _ASM(ox)SEFLES(ph)EDGEVEQQR_
SUZ12 Phosphorylation S583 -0.295 _LYFHSDTCLPLRPQEMEVDS(ph)EDEKDPEWLR_
WHSC1L1 Phosphorylation S561 1.206 _NEKPTQSVSS(ph)PEATSGSTGSVEK_


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