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Query: PRMT8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRMT8 0 0.757 -0.720 1.160 -0.002 -0.505 0.005

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRMT8 Ubiquitylation K134 0.077 0.022 _ANK(gl)LDHVVTIIK_
PRMT8 Ubiquitylation K233 -0.894 _DVAIK(gl)EPLVDVVDPK_

Background Information for PRMT8:


Pubmed-PRMT8 »
Uniprot-PRMT8 »
Biogrid-PRMT8 »
ProteomicsDB-PRMT8 »

Tumorportal-PRMT8 »
COSMIC-PRMT8 »
GenomeRNAi-PRMT8 »
Genecards-PRMT8


Protein-protein Interactions for PRMT8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GIMAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPDEF Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TIGD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZSCAN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRMT8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members tRNA_Trfase_Trm5/Tyw2 IPR003402 0.61
Category members Methyltransf_11 IPR013216 0.2
Category members SAM-dependent_MTases-like IPR029063 0.04
Category members Ribosomal-L11_MeTrfase_PrmA IPR010456 0
Category members Arg_MeTrfase IPR025799 0


Protein complexes (CORUM database) featuring PRMT8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRMT8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0018216 peptidyl-arginine methylation Database 0.1
Category members GO Category GO:0016571 histone methylation Database 0.08
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members GO Category GO:0008469 histone-arginine N-methyltransferase activity Database 0.05
Category members GO Category GO:0043393 regulation of protein binding Database 0.04
Category members GO Category GO:0006479 protein methylation Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008168 methyltransferase activity Database 0
Category members GO Category GO:0008276 protein methyltransferase activity Database 0
Category members GO Category GO:0008757 S-adenosylmethionine-dependent methyltransferase activity Database 0
Category members GO Category GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine Database 0
Category members GO Category GO:0034969 histone arginine methylation Database 0
Category members GO Category GO:0035241 protein-arginine omega-N monomethyltransferase activity Database 0
Category members GO Category GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0


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