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Query: PRMT6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRMT6 0 1.935 -0.440 0.850

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRMT6 Phosphorylation T21 0.891 0.194 _LESGGGGEGGEGT(ph)EEEDGAER_

Background Information for PRMT6:


Pubmed-PRMT6 »
Uniprot-PRMT6 »
Biogrid-PRMT6 »
ProteomicsDB-PRMT6 »

Tumorportal-PRMT6 »
COSMIC-PRMT6 »
GenomeRNAi-PRMT6 »
Genecards-PRMT6


Protein-protein Interactions for PRMT6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PRMT6 Cat. description Hein, Mann, Cell 2015
Category members IP bait AKT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CIRBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDX23 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM19A3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ILF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LEF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LYPD4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MRPL38 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SOST Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCF7L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZFC3H1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRMT6
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members tRNA_Trfase_Trm5/Tyw2 IPR003402 0.61
Category members Methyltransf_11 IPR013216 0.2
Category members SAM-dependent_MTases-like IPR029063 0.04
Category members Small_mtfrase_dom IPR007848 0.01
Category members Ribosomal-L11_MeTrfase_PrmA IPR010456 0
Category members Arg_MeTrfase IPR025799 0
Category members mo5U34_MeTrfas-like IPR027555 0


Protein complexes (CORUM database) featuring PRMT6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring PRMT6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042393 histone binding Database 0.94
Category members GO Category GO:0016571 histone methylation Database 0.08
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members GO Category GO:0006284 base-excision repair Database 0.04
Category members GO Category GO:0006479 protein methylation Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008168 methyltransferase activity Database 0
Category members GO Category GO:0008276 protein methyltransferase activity Database 0
Category members GO Category GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine Database 0
Category members GO Category GO:0034970 histone H3-R2 methylation Database 0
Category members GO Category GO:0035241 protein-arginine omega-N monomethyltransferase activity Database 0
Category members GO Category GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity Database 0
Category members GO Category GO:0042054 histone methyltransferase activity Database 0
Category members GO Category GO:0043985 histone H4-R3 methylation Database 0
Category members GO Category GO:0044020 histone methyltransferase activity (H4-R3 specific) Database 0


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