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Results for the Category
histone methyltransferase activity
(GO:0042054)

RNAi screen result RNAPII IP (MG132) CSB IP CSB IP (MG132) Chrom. Chrom. (MG132) Ubi /Phospo Ubi /Phospho (MG132)
W

Protein Results:

Results for post-translational modifications (below)
Gene name MGoogle Score RNAi high RNAi low RNAPII-IP (MG132) CSB-IP CSB-IP (MG132) Chrom. Chrom. (MG132)
DOT1L 1 -0.340 0.210 -0.710 -0.145
EED 0 -1.210 1.980 0.099 0.896 0.548
EZH2 0 1.100 -0.960 0.524 0.464 -0.045
PRMT1 0 -0.220 0.380 -1.264 0.067
PRMT1 0 -0.220 0.380 -0.002 -0.505 0.005
CARM1 0 -0.160 0.540 -0.032
NSD1 0 -0.750 1.060 -0.118 -0.211
SUZ12 0 -0.710 0.770 0.451 1.156
SUZ12 0 -0.710 0.770 -0.670 0.955 0.457
PRMT6 0 -0.440 0.850

PTM Sites:

Back to Protein Results
Gene name PTM type PTM site UV UV (MG132) Sequence
DOT1L Phosphorylation S374 -0.107 -0.003 _VAGPADAPMDS(ph)GAEEEK_
DOT1L Phosphorylation S448 0.637 0.950 _KNQTALDALHAQTVSQTAASS(ph)PQDAYR_
DOT1L Phosphorylation T772 0.095 _LSGLAAPDYT(ph)RLSPAK_
DOT1L Phosphorylation S775 0.015 -0.688 _LSGLAAPDYTRLS(ph)PAK_
DOT1L Phosphorylation S834 -1.490 -1.900 _PLS(ph)PGALQLAGEK_
DOT1L Phosphorylation S1035 -0.512 -0.045 _GDLPSDSGFS(ph)DPESEAK_
DOT1L Phosphorylation S1104 0.384 -0.103 _RASAGTPSLSAGVS(ph)PK_
DOT1L Phosphorylation S1213 0.118 -0.125 _IATISLESKS(ph)PPK_
DOT1L Phosphorylation S1246 1.598 1.113 _STFS(ph)PISDIGLAK_
EZH2 Ubiquitylation K61 0.548 _TEILNQEWK(gl)QR_
EZH2 Phosphorylation S363 0.010 -0.733 _GRLPNNSS(ph)RPSTPTINVLESK_
EZH2 Phosphorylation S366 -0.266 -0.699 _GRLPNNSSRPS(ph)TPTINVLESK_
EZH2 Phosphorylation T367 0.320 -0.372 _LPNNSSRPST(ph)PTINVLESK_
EZH2 Phosphorylation T369 -0.911 _GRLPNNSSRPSTPT(ph)INVLESK_
EZH2 Phosphorylation T487 -0.501 -0.532 _VKESSIIAPAPAEDVDT(ph)PPR_
EZH2 Ubiquitylation K569 -0.974 _AQCNTK(gl)QCPCYLAVR_
EZH2 Ubiquitylation K713 -0.461 _IGIFAK(gl)R_
EZH2 Ubiquitylation K735 0.038 _YSQADALK(gl)YVGIER_
NSD1 Phosphorylation S1510 0.148 _TATS(ph)PKETVEEGVEHDPGMPASK_
NSD1 Phosphorylation S2471 -0.515 -0.677 _AAS(ph)PHQVTPQADEK_
PRMT1 Ubiquitylation K134 0.077 0.022 _ANK(gl)LDHVVTIIK_
PRMT1 Ubiquitylation K233 -0.894 _DVAIK(gl)EPLVDVVDPK_
PRMT6 Phosphorylation T21 0.891 0.194 _LESGGGGEGGEGT(ph)EEEDGAER_
SUZ12 Ubiquitylation K341 -0.110 -0.960 _ATWETILDGK(gl)R_
SUZ12 Ubiquitylation K390 -0.696 _NSESLHQENK(gl)PGSVKPTQTIAVK_
SUZ12 Phosphorylation S546 0.533 0.248 _ASM(ox)SEFLES(ph)EDGEVEQQR_
SUZ12 Phosphorylation S583 -0.295 _LYFHSDTCLPLRPQEMEVDS(ph)EDEKDPEWLR_


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