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Query: PRMT1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
PRMT1 0 -1.220 -0.220 0.380 -1.264 0.067
PRMT1 0 -1.220 -0.220 0.380 -0.002 -0.505 0.005

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
PRMT1 Ubiquitylation K134 0.077 0.022 _ANK(gl)LDHVVTIIK_
PRMT1 Ubiquitylation K233 -0.894 _DVAIK(gl)EPLVDVVDPK_

Background Information for PRMT1:


Pubmed-PRMT1 »
Uniprot-PRMT1 »
Biogrid-PRMT1 »
ProteomicsDB-PRMT1 »

Tumorportal-PRMT1 »
COSMIC-PRMT1 »
GenomeRNAi-PRMT1 »
Genecards-PRMT1


Protein-protein Interactions for PRMT1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BCLAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CERK Cat. description Hein, Mann, Cell 2015
Category members IP bait FBXO7 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RNPS1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CIRBP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TAF15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in PRMT1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members tRNA_Trfase_Trm5/Tyw2 IPR003402 0.61
Category members Methyltransf_11 IPR013216 0.2
Category members SAM-dependent_MTases-like IPR029063 0.04
Category members Small_mtfrase_dom IPR007848 0.01
Category members Ribosomal-L11_MeTrfase_PrmA IPR010456 0
Category members Arg_MeTrfase IPR025799 0


Protein complexes (CORUM database) featuring PRMT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1231 FIB-associated protein complex Database 0


Categories featuring PRMT1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0045653 negative regulation of megakaryocyte differentiation Database 4.97
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members GO Category GO:0008170 N-methyltransferase activity Database 0.23
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0031175 neuron projection development Database 0.12
Category members GO Category GO:0007166 cell surface receptor signaling pathway Database 0.1
Category members GO Category GO:0018216 peptidyl-arginine methylation Database 0.1
Category members GO Category GO:0016571 histone methylation Database 0.08
Category members GO Category GO:0016740 transferase activity Database 0.07
Category members GO Category GO:0008469 histone-arginine N-methyltransferase activity Database 0.05
Category members GO Category GO:0006479 protein methylation Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008168 methyltransferase activity Database 0
Category members GO Category GO:0008276 protein methyltransferase activity Database 0
Category members GO Category GO:0016274 protein-arginine N-methyltransferase activity Database 0
Category members GO Category GO:0035241 protein-arginine omega-N monomethyltransferase activity Database 0
Category members GO Category GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity Database 0
Category members GO Category GO:0035246 peptidyl-arginine N-methylation Database 0
Category members GO Category GO:0042054 histone methyltransferase activity Database 0
Category members GO Category GO:0043985 histone H4-R3 methylation Database 0
Category members GO Category GO:0044020 histone methyltransferase activity (H4-R3 specific) Database 0


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