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Query: CARM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CARM1 0 0.508 -0.160 0.540 -0.032

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CARM1:


Pubmed-CARM1 »
Uniprot-CARM1 »
Biogrid-CARM1 »
ProteomicsDB-CARM1 »

Tumorportal-CARM1 »
COSMIC-CARM1 »
GenomeRNAi-CARM1 »
Genecards-CARM1


Protein-protein Interactions for CARM1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ALDOA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ARFGAP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATP6V1G1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C1orf94 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C22orf33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CNN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DGCR14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ETV4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FOSL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTSE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HEY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HN1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HRSP12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1F6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA0284 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1191 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIAA1683 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KIF16B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MED9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NECAP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRCC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RAB39B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SH3BP5L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TICAM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VASN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CARM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Methyltransf_11 IPR013216 0.2
Category members SAM-dependent_MTases-like IPR029063 0.04
Category members Small_mtfrase_dom IPR007848 0.01
Category members Ribosomal-L11_MeTrfase_PrmA IPR010456 0
Category members Arg_MeTrfase IPR025799 0
Category members mo5U34_MeTrfas-like IPR027555 0


Protein complexes (CORUM database) featuring CARM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 86 NUMAC complex (nucleosomal methylation activator complex) Database 0.83


Categories featuring CARM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0070577 histone acetyl-lysine binding Database 0.88
Category members Pathway Pathway_308 PID_AR_TF_PATHWAY 0 0.86
Category members Pathway Pathway_880 PID_AR_PATHWAY 0 0.58
Category members GO Category GO:0008013 beta-catenin binding Database 0.35
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_383 PID_P53_DOWNSTREAM_PATHWAY 0 0.23
Category members Pathway Pathway_945 BIOCARTA_VDR_PATHWAY 0 0.22
Category members Pathway Pathway_948 BIOCARTA_CARM1_PATHWAY 0 0.17
Category members GO Category GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity Database 0.12
Category members GO Category GO:0016571 histone methylation Database 0.08
Category members GO Category GO:0032091 negative regulation of protein binding Database 0.08
Category members GO Category GO:0030520 intracellular estrogen receptor signaling pathway Database 0.06
Category members Pathway Pathway_639 BIOCARTA_HER2_PATHWAY 0 0.01
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members Pathway Pathway_365 BIOCARTA_CARM_ER_PATHWAY 0 0
Category members GO Category GO:0003420 regulation of growth plate cartilage chondrocyte proliferation Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0006479 protein methylation Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0008168 methyltransferase activity Database 0
Category members GO Category GO:0008276 protein methyltransferase activity Database 0
Category members GO Category GO:0008284 positive regulation of cell proliferation Database 0
Category members GO Category GO:0009405 pathogenesis Database 0
Category members GO Category GO:0016274 protein-arginine N-methyltransferase activity Database 0
Category members GO Category GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine Database 0
Category members GO Category GO:0030518 intracellular steroid hormone receptor signaling pathway Database 0
Category members GO Category GO:0033146 regulation of intracellular estrogen receptor signaling pathway Database 0
Category members GO Category GO:0034969 histone arginine methylation Database 0
Category members GO Category GO:0034970 histone H3-R2 methylation Database 0
Category members GO Category GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity Database 0
Category members GO Category GO:0035246 peptidyl-arginine N-methylation Database 0
Category members GO Category GO:0042054 histone methyltransferase activity Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0044255 cellular lipid metabolic process Database 0
Category members GO Category GO:0045600 positive regulation of fat cell differentiation Database 0
Category members GO Category GO:0051591 response to cAMP Database 0
Category members GO Category GO:0060350 endochondral bone morphogenesis Database 0


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