bioLOGIC-db

bioLOGIC Data

Query: EED

[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
EED	0	3.523	-1.210	1.980	0.099			0.896	0.548

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence

Pubmed-EED »

Biogrid-EED »

ProteomicsDB-EED »

COSMIC-EED »

Genecards-EED

Protein-protein Interactions for EED

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait C10orf12	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait EED	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait EZH2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait HDAC1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait NR2C2	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait PLK1	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait RPL35	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait SRP72	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait AEBP2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait BTRC	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait CLASRP	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FBXW11	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait INTU	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait PHF19	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RBBP7	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SUZ12	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in EED

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	WD40_repeat_dom	IPR017986	1.39
Category members	WD40_repeat	IPR001680	0.52

Protein complexes (CORUM database) featuring EED

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	Corum	105	Polycomb repressive complex 2 (PRC 2)	Database	0.57
Category members	Corum	995	Polycomb repressive complex 3 (PRC3)	Database	0.57
Category members	Corum	996	Polycomb repressive complex 2 (PRC2)	Database	0.57
Category members	Corum	974	EED-EZH2 complex	Database	0.31
Category members	Corum	5502	EED-EZH-YY1 polycomb complex	Database	0.04
Category members	Corum	1177	Polycomb repressive complex 4 (PRC4)	Database	0
Category members	Corum	5521	EED-EZH polycomb complex	Database	0

Categories featuring EED

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0003682	chromatin binding	Database	6.07
Category members	GO Category	GO:0006349	regulation of gene expression by genetic imprinting	Database	1.64
Category members	GO Category	GO:0001739	sex chromatin	Database	1.47
Category members	GO Category	GO:0045892	negative regulation of transcription, DNA-dependent	Database	1.15
Category members	GO Category	GO:0006351	transcription, DNA-templated	Database	1.07
Category members	GO Category	GO:0035098	ESC/E(Z) complex	Database	0.47
Category members	GO Category	GO:0045120	pronucleus	Database	0.27
Category members	GO Category	GO:0042802	identical protein binding	Database	0.26
Category members	GO Category	GO:0016571	histone methylation	Database	0.08
Category members	GO Category	GO:0042054	histone methyltransferase activity	Database	0
Category members	GO Category	GO:0061087	positive regulation of histone H3-K27 methylation	Database	0