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Query: KMT2C

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KMT2C 0 -0.114 0.730 0.280 -1.099 0.032 -0.195

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KMT2C Phosphorylation S2811 0.831 0.317 _TLVLSDKHS(ph)PQK_
KMT2C Phosphorylation S4034 -1.421 -1.557 _EEPPEPVPS(ph)PIIPILPSTAGK_

Background Information for KMT2C:


Pubmed-KMT2C »
Uniprot-KMT2C »
Biogrid-KMT2C »
ProteomicsDB-KMT2C »

Tumorportal-KMT2C »
COSMIC-KMT2C »
GenomeRNAi-KMT2C »
Genecards-KMT2C


Protein-protein Interactions for KMT2C
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in KMT2C
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members HMG_box_dom IPR009071 0.31
Category members SET_dom IPR001214 0.29
Category members FYrich_N IPR003888 0.17
Category members FYrich_C IPR003889 0.17
Category members Znf_DHHC_palmitoyltrfase IPR001594 0.04
Category members Post-SET_dom IPR003616 0.03
Category members Znf_RING IPR001841 0


Protein complexes (CORUM database) featuring KMT2C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5195 PTIP-HMT complex Database 0.33
Category members Corum 1400 ASCOM complex Database 0
Category members Corum 3075 UTX-MLL2/3 complex Database 0


Categories featuring KMT2C
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0051568 histone H3-K4 methylation Database 1.7
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042800 histone methyltransferase activity (H3-K4 specific) Database 0.73
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0035097 histone methyltransferase complex Database 0.26
Category members GO Category GO:0016571 histone methylation Database 0.08
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0008168 methyltransferase activity Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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