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Query: SETD8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
SETD8 1 1.557 -0.030 0.060
SETD8 1 1.557 0.220 0.320

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
SETD8 Ubiquitylation K275 2.687 _GVIATK(gl)QFSR_
SETD8 Ubiquitylation K236 -1.450 2.341 _SK(gl)AELQSEER_
SETD8 Ubiquitylation K234 2.165 _K(gl)SKAELQSEER_
SETD8 Ubiquitylation K267 2.000 _IDLIDGK(gl)GR_
SETD8 Ubiquitylation K342 1.991 _LINHSK(gl)CGNCQTK_

Background Information for SETD8:





Protein-protein Interactions for SETD8

Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in SETD8

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members SET_dom IPR001214 0.29


Protein complexes (CORUM database) featuring SETD8

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring SETD8

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005694 chromosome Database 3.87
Category members Pathway Pathway_416 PID_P53_REGULATION_PATHWAY 0 2.29
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0002039 p53 binding Database 2.06
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0034968 histone lysine methylation Database 1.1
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0018024 histone-lysine N-methyltransferase activity Database 0.73
Category members GO Category GO:0018026 peptidyl-lysine monomethylation Database 0.05
Category members GO Category GO:0016279 protein-lysine N-methyltransferase activity Database 0.04
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator Database 0


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