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Query: ASH1L

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ASH1L 0 -2.481 1.230 -0.360 -0.777 -0.350

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ASH1L Phosphorylation S1748 -0.660 -0.694 _SIDAVIATASAPPSSS(ph)PGR_

Background Information for ASH1L:


Pubmed-ASH1L »
Uniprot-ASH1L »
Biogrid-ASH1L »
ProteomicsDB-ASH1L »

Tumorportal-ASH1L »
COSMIC-ASH1L »
GenomeRNAi-ASH1L »
Genecards-ASH1L


Protein-protein Interactions for ASH1L
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait PARD6A Cat. description Hein, Mann, Cell 2015
Category members IP bait SET Cat. description Hein, Mann, Cell 2015
Category members IP bait SIKE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UFL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MORF4L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NXF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THAP7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ASH1L
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Bromodomain IPR001487 1.43
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members BAH_dom IPR001025 0.62
Category members SET_dom IPR001214 0.29
Category members Post-SET_dom IPR003616 0.03
Category members AWS_dom IPR006560 0
Category members AT_hook_DNA-bd_motif IPR017956 0


Protein complexes (CORUM database) featuring ASH1L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ASH1L
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0005694 chromosome Database 3.87
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0007267 cell-cell signaling Database 0.94
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0018024 histone-lysine N-methyltransferase activity Database 0.73
Category members GO Category GO:0005923 tight junction Database 0.69
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members Disease phenotype Intellectual_disability Intellectual disability Database 0.04
Category members GO Category GO:0006323 DNA packaging Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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