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Query: CXXC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
CXXC1 0 0.992 -0.510 0.300 0.959 0.654 -0.921

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for CXXC1:


Pubmed-CXXC1 »
Uniprot-CXXC1 »
Biogrid-CXXC1 »
ProteomicsDB-CXXC1 »

Tumorportal-CXXC1 »
COSMIC-CXXC1 »
GenomeRNAi-CXXC1 »
Genecards-CXXC1


Protein-protein Interactions for CXXC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BOD1L1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CXXC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SEPT7 Cat. description Hein, Mann, Cell 2015
Category members IP bait SETD1B Cat. description Hein, Mann, Cell 2015
Category members IP bait WDR5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CAMK2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CXXC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EDA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait H2AFX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HCFC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MDK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP50 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PES1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIP4K2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRMT2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSMC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RSBN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF408 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in CXXC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_FYVE_PHD IPR011011 1.23
Category members Znf_PHD IPR001965 1.15
Category members Znf_PHD-finger IPR019787 0.91
Category members Znf_CXXC IPR002857 0


Protein complexes (CORUM database) featuring CXXC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring CXXC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0016607 nuclear speck Database 4.84
Category members GO Category GO:0016363 nuclear matrix Database 1.89
Category members GO Category GO:0051568 histone H3-K4 methylation Database 1.7
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0030968 endoplasmic reticulum unfolded protein response Database 1.35
Category members GO Category GO:0006987 activation of signaling protein activity involved in unfolded protein response Database 1.26
Category members Pathway Pathway_147 REACTOME_UNFOLDED_PROTEIN_RESPONSE 0 1.08
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042800 histone methyltransferase activity (H3-K4 specific) Database 0.73
Category members GO Category GO:0048188 Set1C/COMPASS complex Database 0.64
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0008270 zinc ion binding Database 0.29
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0035097 histone methyltransferase complex Database 0.26
Category members GO Category GO:0045322 unmethylated CpG binding Database 0.13
Category members Pathway Pathway_148 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S 0 0.11
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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